Explore popular drugs in clinical trials

Check which drugs are currently being frequently studied.

See also our rare diseases glossary and popular diseases list.

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Most popular drugs

The list below features the most popular substances currently involved in ongoing clinical trials.

Drug	trials
Pembrolizumab	441
Sodium Chloride	403
Carboplatin	329
Cisplatin	274
Paclitaxel	245
Fluorouracil	226
Oxaliplatin	218
Nivolumab	205
Dexamethasone	203
Rituximab	189
Cyclophosphamide	183
Durvalumab	157
Bevacizumab	157
Paracetamol	154
Capecitabine	152
Atezolizumab	145
Docetaxel	127
Prednisone	125
Tocilizumab	120
Prednisolone	116
Gemcitabine	114
Venetoclax	113
Etoposide	113
Mycophenolate Mofetil	111
Pemetrexed	109
Doxorubicin Hydrochloride	104
Lenalidomide	97
Infliximab	93
Ipilimumab	89
Acetylsalicylic Acid	87
Folinic Acid	87
Semaglutide	86
Placebo	83
Paclitaxel Albumin-Bound	81
Methotrexate	77
Cytarabine	77
Daratumumab	77
Fludarabine Phosphate	75
Calcium Folinate	74
Letrozole	73
Bortezomib	70
Olaparib	70
Gemcitabine Hydrochloride	68
Dapagliflozin	66
Obinutuzumab	65
Trastuzumab	65
Azacitidine	65
Fulvestrant	62
Cetuximab	61
Tacrolimus	61
Methylprednisolone	61
Lenvatinib	60
Irinotecan	58
Irinotecan Hydrochloride Trihydrate	58
Vincristine Sulfate	57
Temozolomide	56
Cemiplimab	54
Trastuzumab Deruxtecan	53
Enzalutamide	51
Apixaban	49
Dexamethasone Sodium Phosphate	49
Codeine Phosphate	48
Betamethasone Sodium Phosphate	48
Lidocaine Hydrochloride Monohydrate	47
Exemestane	47
Buclizine Hydrochloride	46
Anastrozole	46
Potassium Chloride	46
Empagliflozin	46
Hydrocortisone	45
Lidocaine Hydrochloride	45
Amoxicillin	44
Ribociclib	44
Doxorubicin	43
Pertuzumab	43
Adalimumab	43
Clopidogrel	42
Ruxolitinib	41
Tenofovir Alafenamide	41
Rivaroxaban	41
Abemaciclib	41
Ibrutinib	40
Oxygen	40
Pomalidomide	40
Clavulanic Acid	39
Atorvastatin	39
Ropivacaine Hydrochloride	39
Metformin Hydrochloride	39
Ifosfamide	38
Carfilzomib	38
Palbociclib	38
Propofol	38
Bendamustine Hydrochloride	38
Emtricitabine	37
Acalabrutinib	37
Dostarlimab	37
Cyclophosphamide Monohydrate	37
Pemetrexed Disodium	37
Dexamethasone Phosphate	36
Sulfamethoxazole	36

New drugs in trials

The list below features the new substances involved to ongoing clinical trials.

#1 AZD0120

Clinical trials are investigating AZD0120 in people with relapsed or refractory multiple myeloma, a cancer that has returned or no longer responds to treatment.

1 week ago

#2 STREPTOCOCCUS VIRIDANS

Clinical trials investigating "STREPTOCOCCUS VIRIDANS" are studying whether a related study treatment can reduce respiratory infections in children.

1 week ago

#3 STREPTOCOCCUS PYOGENES

Clinical trials investigating STREPTOCOCCUS PYOGENES are studying a treatment called PMBL (Ismigen) in children with respiratory tract infections.

1 week ago

#4 AZD1163

Clinical trials are investigating AZD1163 in adults with moderately to severely active rheumatoid arthritis.

1 week ago

#5 AZD5335

Clinical trials are investigating AZD5335 in women with advanced platinum-resistant epithelial ovarian cancer.

1 week ago

#6 IMB 101

Clinical trials are studying NAV-240 in adults with moderate-to-severe hidradenitis suppurativa.

1 week ago

Drugs starting by a

2
Azd3427

Cardiovascular Diseases, Diseases

Clinical trials are investigating Azd3427 in people with heart failure and related circulation problems. These studies look at whether it can improve blood flow in the lungs and kidneys, and they measure safety and treatment effect in specific patient groups.

Related diseases and areas:
1
Azd3470

Diseases, Neoplasms

Clinical trials are investigating Azd3470 in people with advanced solid tumours that are MTAP deficient. The studies are looking at safety, tolerability, and the recommended dose for later testing, both as a single treatment and with anti-cancer medicines.

Related diseases and areas:
- Neoplasm malignant
1
AZD3632

Diseases, Neoplasms

Clinical trials are investigating AZD3632 in adults with relapsed or refractory acute leukemia and myelodysplastic syndromes with HOX gene overexpression. These studies aim to assess safety, tolerability, how the treatment works, and how it moves through the body over time. The trial is in Phase 1/2 and includes people with advanced blood cancers.

Related diseases and areas:
1
AZD4360

Diseases, Neoplasms

Clinical trials are investigating AZD4360 in adults with advanced solid tumors, including certain stomach, bile duct, and pancreatic cancers. The studies aim to learn about safety, how well AZD4360 works, and how it moves through the body. They also look for a dose that can be used in later studies.

Related diseases and areas:
2
AZD4512

Diseases, Hemic and Lymphatic Diseases

Clinical trials are studying AZD4512 in people with B-cell blood cancers. These studies aim to learn about safety, tolerability, and how well AZD4512 may work in non-Hodgkin lymphoma and B-cell acute lymphoblastic leukemia. The trials include adults with relapsed or refractory disease, meaning the cancer came back or did not respond well to past treatment.
1
Azd4831

Diseases, Metabolism, Nutritional and Metabolic Diseases, Pathological Conditions, Signs and Symptoms, Phenomena and Processes

Clinical trials are investigating Azd4831 in adults with non-cirrhotic NASH with fibrosis. These studies are looking at safety, tolerability, and pharmacodynamics, which means how the treatment affects the body. The trial data focus on people with liver disease linked to fatty liver and fibrosis.

Related diseases and areas:
- Hepatic cirrhosis
2
Azd5004

Diseases, Nutritional and Metabolic Diseases

AZD5004 is a novel drug currently undergoing clinical trials for the treatment of obesity and type 2 diabetes. This article explores the ongoing research into AZD5004’s safety, efficacy, and potential benefits for patients struggling with weight management and blood sugar control. We’ll examine the various phases of clinical trials and what they aim to discover about this promising new medication.

Related diseases and areas:
1
AZD5148

Bacterial Infections and Mycoses, Diseases

Clinical trials are investigating HUMANISED IGG1 KAPPA (YTE) MONOCLONAL ANTIBODY AGAINST CLOSTRIDIOIDES DIFFICILE, TOXIN B in people with recurrence of Clostridioides difficile infection. The study aims to evaluate efficacy against recurrence, with a focus on patients receiving standard antibacterial treatment. This article summarizes the trial design, phase, target population, and main outcome being measured.
1
AZD5335

Diseases, Pathological Conditions, Signs and Symptoms

Clinical trials are investigating AZD5335 in women with advanced platinum-resistant epithelial ovarian cancer. The studies are looking at how well AZD5335 works compared with other treatments, and they also measure safety and disease control. One large phase 3 trial is separating patients by FRα tumor level.

Related diseases and areas:
- Ovarian epithelial cancer
1
Azd5462

Cardiovascular Diseases, Diseases

Clinical trials are investigating Azd5462 in people with chronic heart failure. These studies are looking at whether different doses are safe and effective, especially in stable patients. The main goal is to see how heart structure and function change during treatment.

Related diseases and areas:
- Cardiac failure chronic
1
Azd5492

Diseases, Hemic and Lymphatic Diseases

Clinical trials are investigating Azd5492 in adults with B-cell blood cancers. These studies aim to learn whether Azd5492 is safe and whether it may work alone or with other cancer treatments. The trial data shown here focuses on people with relapsed or refractory B-cell malignancies.

Related diseases and areas:
- Neoplasm malignant
1
Azd5863

Analytical, Diagnostic and Therapeutic Techniques and Equipment, Diseases, Neoplasms, Surgical Procedures, Operative

Clinical trials are investigating Azd5863 in adults with advanced or metastatic solid tumors, including tumors with CLDN18.2 expression. These studies are looking at safety, tolerability, dose finding, and early signs of antitumor activity in phase 1/2 research.

Related diseases and areas:
- Neoplasm malignant
2
AZD6234

Diseases, Nutritional and Metabolic Diseases

Clinical trials are investigating AZD6234 as part of studies for weight loss in people with obesity or overweight. These trials look at safety, tolerability, and how well AZD6234 works alone or with AZD9550. The studies include adults with obesity or overweight, with or without type 2 diabetes.

Related diseases and areas:
2
Azd7798

Digestive System Diseases, Diseases, Immune System Diseases

Azd7798 is being studied in clinical trials for Crohn’s disease, including adults with ileal Crohn’s disease who have an ileostomy. These trials are checking safety, tolerability, and how well Azd7798 may help people reach remission.

Related diseases and areas:
- Crohn’s disease
1
Azd8205

Diseases, Neoplasms

Clinical trials are investigating Azd8205 in people with advanced or metastatic solid cancers, including B7-H4-selected endometrial cancer. These studies aim to assess safety, tolerability, and how well Azd8205 works, including the best dose and survival outcomes.

Related diseases and areas:
1
Azd8421

Diseases, Neoplasms

This article discusses a groundbreaking clinical trial investigating the use of AZD8421, a new drug being tested for treating advanced or metastatic solid tumors. The study focuses on patients with ER+HER2- advanced breast cancer and high-grade serous ovarian cancer. The trial aims to assess the safety, effectiveness, and how the body processes AZD8421 when used alone or in combination with other cancer drugs.

Related diseases and areas:
- Ovarian cancer
- Hormone receptor positive H…
1
Azd8630

Diseases, Respiratory Tract Diseases

AZD8630 is an experimental drug being studied for the treatment of asthma. This article summarizes the ongoing clinical trials evaluating the safety, effectiveness, and proper dosing of AZD8630 in healthy volunteers and patients with asthma. The trials aim to determine if AZD8630 can improve asthma control and reduce exacerbations when added to standard asthma medications.

Related diseases and areas:
- Asthma
2
Azd9550

Digestive System Diseases, Diseases, Nutritional and Metabolic Diseases

AZD9550 is an investigational drug currently undergoing clinical trials for the treatment of Non-alcoholic Steatohepatitis (NASH), a severe form of liver disease often associated with obesity and type 2 diabetes. These trials aim to assess the safety, tolerability, and effectiveness of AZD9550 in various patient populations, including healthy individuals and those with obesity or diabetes. The studies are designed to evaluate different dosing regimens and administration methods, providing valuable insights into the drug’s potential as a new therapeutic option for NASH.

Related diseases and areas:
1
Azelastine

Immune System Diseases

Clinical trials involving Azelastine are studying how it performs in people with allergic eye and nose symptoms. The trial data here focuses on adult patients with moderate to severe allergic rhinitis/rhinoconjunctivitis, sometimes with asthma, and measures symptom control and treatment effect.

Related diseases and areas:
- Conjunctivitis allergic
- Rhinitis allergic
2
Azelastine Hydrochloride

Behavioral Disciplines and Activities, Immune System Diseases

Azelastine Hydrochloride, a potent antihistamine, has been the subject of several clinical trials aimed at evaluating its effectiveness in treating various allergic conditions, particularly allergic rhinitis and conjunctivitis. These studies have explored its use alone and in combination with other medications, comparing its efficacy to placebos and other active treatments. The trials have focused on symptom relief, onset of action, and overall quality of life improvements for patients suffering from seasonal and perennial allergies.

Related diseases and areas:
5
Azenosertib

Diseases, Neoplasms

Azenosertib, also known as ZN-c3, is an innovative drug currently being studied in clinical trials for various types of cancer. This article explores the ongoing research into Azenosertib’s potential as a treatment for uterine serous carcinoma, triple-negative breast cancer, pancreatic cancer, and other solid tumors. We’ll look at how it works, its combination with other drugs, and what these trials mean for cancer patients.

Related diseases and areas:
8
Azetukalner

Diseases, Mental Disorders, Nervous System Diseases, Psychiatry and Psychology

Azetukalner is an innovative drug currently being studied in clinical trials for the treatment of Major Depressive Disorder (MDD). This article explores the ongoing research, specifically focusing on a Phase 3 clinical trial called X-NOVA2, which aims to evaluate the efficacy, safety, and tolerability of Azetukalner in adults with moderate-to-severe MDD.

Related diseases and areas:
- Generalised tonic-clonic se…
- Partial seizures
2
Azilsartan Medoxomil

Cardiovascular Diseases, Immune System Diseases

Clinical trials investigating Azilsartan Medoxomil are studying how it is used in research settings for different patient groups. The trial data here includes studies in heart failure and focal segmental glomerulosclerosis, with goals such as measuring efficacy, safety, and dose response. These studies involve adults receiving standard treatment or an ARB.

Related diseases and areas:
- Focal segmental glomerulosc…
- Cardiac failure
16
Azithromycin

Bacterial Infections and Mycoses, Biological Phenomena, Cell Physiological Phenomena, Diseases, Female Urogenital Diseases and Pregnancy Complications, Otorhinolaryngologic Diseases, Phenomena and Processes, Physical Phenomena, Respiratory Tract Diseases

Azithromycin is a versatile antibiotic that has been studied in clinical trials for its potential benefits in treating various medical conditions. This article explores the use of azithromycin in different clinical settings, from respiratory infections to genetic disorders, highlighting its diverse applications and potential therapeutic effects beyond its traditional antibiotic role.

Related diseases and areas:
3
Azithromycin Dihydrate

Bacterial Infections and Mycoses, Diseases, Female Urogenital Diseases and Pregnancy Complications, Neoplasms, Respiratory Tract Diseases

This article explores the use of Azithromycin Dihydrate in clinical trials for various medical conditions. Azithromycin is an antibiotic medication that has been studied for its potential benefits in treating lung transplant complications, eye infections, and inflammatory bowel diseases. We’ll examine the key findings from these trials and discuss how this drug may impact patient care in different medical fields.

Related diseases and areas:
11
Aztreonam

Analytical, Diagnostic and Therapeutic Techniques and Equipment, Anesthesia and Analgesia, Bacterial Infections and Mycoses, Diseases, Nervous System Diseases, Respiratory Tract Diseases, Skin and Connective Tissue Diseases

Aztreonam is an antibiotic medication that has been the subject of several clinical trials exploring its potential uses in treating various infections. This article summarizes key findings from recent clinical trials investigating aztreonam, particularly its inhaled formulation, for conditions like cystic fibrosis, bronchiectasis, and other bacterial infections. We’ll examine the drug’s efficacy, safety profile, and potential applications based on these clinical studies.

Related diseases and areas:

Explore popular drugs in clinical trials

Starting by letter

Most popular drugs

New drugs in trials

#1 AZD0120

#2 STREPTOCOCCUS VIRIDANS

#3 STREPTOCOCCUS PYOGENES

#4 AZD1163

#5 AZD5335

#6 IMB 101

Drugs starting by a

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