Explore popular drugs in clinical trials

Check which drugs are currently being frequently studied.

See also our rare diseases glossary and popular diseases list.

Starting by letter

To open the drugs glossary, select a letter from the list below.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All drugs

Most popular drugs

The list below features the most popular substances currently involved in ongoing clinical trials.

Drug	Trials
Pembrolizumab	449
Sodium Chloride	415
Carboplatin	338
Cisplatin	282
Paclitaxel	251
Fluorouracil	232
Oxaliplatin	223
Nivolumab	210
Dexamethasone	205
Rituximab	194
Cyclophosphamide	187
Durvalumab	162
Bevacizumab	161
Capecitabine	157
Paracetamol	156
Atezolizumab	145
Docetaxel	128
Prednisone	127
Tocilizumab	125
Prednisolone	121
Gemcitabine	117
Venetoclax	116
Mycophenolate Mofetil	115
Pemetrexed	114
Etoposide	114
Doxorubicin Hydrochloride	109
Infliximab	99
Lenalidomide	98
Ipilimumab	90
Semaglutide	90
Folinic Acid	89
Acetylsalicylic Acid	88
Placebo	85
Paclitaxel Albumin-Bound	84
Daratumumab	79
Cytarabine	79
Calcium Folinate	78
Methotrexate	78
Fludarabine Phosphate	77
Letrozole	72
Bortezomib	72
Olaparib	70
Gemcitabine Hydrochloride	69
Dapagliflozin	68
Obinutuzumab	67
Azacitidine	66
Trastuzumab	65
Tacrolimus	63
Cetuximab	63
Lenvatinib	62
Fulvestrant	62
Methylprednisolone	61
Irinotecan	61
Irinotecan Hydrochloride Trihydrate	59
Temozolomide	59
Cemiplimab	57
Vincristine Sulfate	57
Trastuzumab Deruxtecan	53
Apixaban	51
Enzalutamide	51
Betamethasone Sodium Phosphate	50
Lidocaine Hydrochloride Monohydrate	50
Dexamethasone Sodium Phosphate	49
Codeine Phosphate	49
Amoxicillin	47
Buclizine Hydrochloride	47
Lidocaine Hydrochloride	47
Exemestane	46
Potassium Chloride	46
Empagliflozin	46
Hydrocortisone	45
Anastrozole	45
Adalimumab	45
Ribociclib	44
Pomalidomide	43
Pertuzumab	43
Doxorubicin	43
Clavulanic Acid	42
Oxygen	42
Clopidogrel	42
Rivaroxaban	41
Ibrutinib	41
Tenofovir Alafenamide	41
Ruxolitinib	41
Ropivacaine Hydrochloride	40
Abemaciclib	40
Atorvastatin	40
Trimethoprim	39
Metformin Hydrochloride	39
Bendamustine Hydrochloride	39
Carfilzomib	39
Cyclophosphamide Monohydrate	39
Sulfamethoxazole	39
Palbociclib	38
Linezolid	38
Ifosfamide	38
Pemetrexed Disodium	38
Propofol	38
Dostarlimab	37
Acalabrutinib	37

New drugs in trials

The list below features the new substances involved to ongoing clinical trials.

#1 VMX-C001

Clinical trials are studying VMX-C001 in people who take a Factor Xa direct oral anticoagulant and need urgent surgery or another high-bleeding-risk procedure.

4 weeks ago

#2 LIPASE

Clinical trials are investigating LIPASE, including a new lipase product compared with pancrelipase.

4 weeks ago

#3 TRIACYLGLYCEROL LIPASE

Clinical trials of TRIACYLGLYCEROL LIPASE are studying a new lipase treatment in adults with exocrine pancreatic insufficiency.

4 weeks ago

#4 IMA401

Clinical trials are investigating IMA401 in patients with recurrent and/or refractory solid tumors.

4 weeks ago

#5 ALLERGEN EXTRACTS

Clinical trials are studying BLOMIA TROPICALIS POLYMERIZED EXTRACT as part of a vaccine for dust mite and Blomia tropicalis allergy.

4 weeks ago

#6 AUR200

Clinical trials are investigating AUR200 in people with generalized myasthenia gravis.

4 weeks ago

All drugs

10
Tenecteplase

Cardiovascular Diseases, Diseases, Eye Diseases, Nervous System Diseases

Tenecteplase, a thrombolytic drug, is being extensively studied in clinical trials for its potential in treating acute ischemic stroke. These trials aim to evaluate its efficacy, safety, and optimal dosing compared to standard treatments. Researchers are exploring its use in various time windows after stroke onset and in combination with other therapies like endovascular thrombectomy.

Related diseases and areas:
41
Tenofovir Alafenamide

Digestive System Diseases, Diseases, Immune System Diseases, Immune system processes, Nervous System Diseases, Pathological Conditions, Signs and Symptoms, Phenomena and Processes, Virus Diseases

This article explores the use of Tenofovir Alafenamide (TAF) in clinical trials for treating chronic hepatitis B (CHB) and HIV. TAF is a newer formulation of tenofovir that offers improved efficacy and safety profiles compared to older treatments. The trials examine TAF’s effectiveness in viral suppression, liver health improvement, and reduction of side effects, particularly related to kidney function and bone density.

Related diseases and areas:
23
Tenofovir Disoproxil

Digestive System Diseases, Diseases, Health Care Quality, Access, and Evaluation, Immune System Diseases, Pathological Conditions, Signs and Symptoms, Virus Diseases

This article explores the use of Tenofovir Disoproxil, a potent antiviral medication, in clinical trials for the treatment of chronic hepatitis B. We’ll examine its effectiveness, safety profile, and potential benefits compared to other treatments across various patient populations and study designs.

Related diseases and areas:
3
Tenofovir Disoproxil Fumarate

Digestive System Diseases, Diseases, Virus Diseases

This article examines the use of Tenofovir Disoproxil Fumarate (TDF) in clinical trials for the treatment of chronic hepatitis B. TDF is an antiviral medication that has shown promise in suppressing hepatitis B virus (HBV) replication and improving liver health in patients with chronic HBV infection. The trials discussed here evaluate TDF’s efficacy, safety, and optimal dosing in various patient populations, including treatment-naïve patients, those who have failed previous therapies, and special groups like pregnant women. By reviewing these clinical studies, we can gain insights into TDF’s potential as a key treatment option for chronic hepatitis B.

Related diseases and areas:
- HIV infection
- Metabolic dysfunction-assoc…
2
Teplizumab

Diseases, Nutritional and Metabolic Diseases

Teplizumab is an innovative drug being studied in clinical trials for its potential to delay or prevent the onset of type 1 diabetes (T1D). This article explores the use of teplizumab in various clinical trials, focusing on its efficacy, safety, and potential benefits for individuals at risk of developing T1D or those recently diagnosed with the condition.

Related diseases and areas:
- Diabetes mellitus
7
Tepotinib

Diseases, Neoplasms

Tepotinib is an investigational drug being studied in clinical trials for the treatment of various types of cancer, particularly non-small cell lung cancer (NSCLC) with specific genetic alterations. This article summarizes key findings from several clinical trials evaluating tepotinib’s safety, efficacy, and pharmacokinetics in cancer patients and healthy volunteers. The trials explore tepotinib as both a monotherapy and in combination with other drugs for patients with MET gene alterations and other biomarkers.

Related diseases and areas:
1
Teprenone

Cardiovascular Diseases, Diseases

Teprenone, also known as geranylgeranylacetone (GGA), is a drug that has been the subject of several clinical trials investigating its potential benefits in various medical conditions. These trials have primarily focused on its effects on gastric health, including the prevention of ulcers and treatment of gastritis, as well as its potential role in heart failure management. The studies aim to evaluate Teprenone’s efficacy, safety, and mechanisms of action in comparison to other treatments or placebos.

Related diseases and areas:
- Atrial fibrillation
2
Teprotumumab

Diseases, Eye Diseases

Teprotumumab, also known as Tepezza, is a groundbreaking drug being studied in clinical trials for the treatment of Thyroid Eye Disease (TED). This article explores the various clinical trials investigating the efficacy, safety, and administration methods of teprotumumab in patients with TED and other conditions. We’ll delve into the drug’s potential benefits, its mechanism of action, and the ongoing research to optimize its use in medical practice.

Related diseases and areas:
- Endocrine ophthalmopathy
2
Terbinafine

Bacterial Infections and Mycoses, Diseases, Virus Diseases

This article examines the use of terbinafine, an antifungal medication, in various clinical trials. Terbinafine has been studied for treating conditions like onychomycosis (nail fungus), tinea pedis (athlete’s foot), and tinea capitis (scalp ringworm). The trials investigate different formulations, including oral tablets, topical creams, nail lacquers, and film-forming solutions. Researchers aim to assess the drug’s effectiveness, safety, and optimal treatment durations for these fungal infections.

Related diseases and areas:
- Chronic hepatitis B
- Onychomycosis
2
Terbinafine Hydrochloride

Bacterial Infections and Mycoses, Diseases

Terbinafine Hydrochloride, commonly known as Lamisil, is an antifungal medication that has been the subject of several clinical trials. These studies aim to evaluate its effectiveness, safety, and new delivery methods for treating various fungal infections, particularly onychomycosis (toenail fungus) and tinea capitis (scalp ringworm). The trials explore different formulations, including oral tablets, topical solutions, and innovative delivery systems, to improve treatment outcomes for patients with these persistent fungal conditions.

Related diseases and areas:
- Fungal infection
- Onychomycosis
12
Teriflunomide

Diseases, Nervous System Diseases

Teriflunomide, marketed under the brand name Aubagio, is an oral medication that has shown promise in the treatment of multiple sclerosis (MS) and other autoimmune conditions. This article explores the use of teriflunomide in various clinical trials, examining its efficacy, safety, and potential benefits for patients with relapsing forms of MS and other disorders.

Related diseases and areas:
3
Teriparatide

Diseases, Musculoskeletal and Neural Physiological Phenomena, Musculoskeletal Diseases, Phenomena and Processes

This article explores the use of teriparatide, a medication used to treat osteoporosis, in various clinical trials. Teriparatide, also known by brand names like Forteo and Forsteo, is a synthetic form of parathyroid hormone that stimulates new bone formation. The trials discussed here investigate its effectiveness, safety, and potential applications in different patient populations and treatment scenarios.

Related diseases and areas:
1
Terlipressin

Diseases, Respiratory Tract Diseases

Terlipressin is a synthetic vasopressin analog that has been the subject of several clinical trials exploring its potential benefits in treating various medical conditions. This article examines the use of terlipressin in clinical trials for conditions such as portal hypertension, septic shock, hepatorenal syndrome, and surgical procedures like myomectomy. We’ll look at how terlipressin compares to other treatments and its effects on patient outcomes.

Related diseases and areas:
- Haemoptysis
2
Terlipressin Acetate

Bacterial Infections and Mycoses, Diseases, Pathological Conditions, Signs and Symptoms

Terlipressin Acetate is a drug being studied in clinical trials for its potential benefits in treating cirrhosis, portal hypertension, and related complications such as refractory ascites. These trials aim to evaluate the safety, efficacy, and hemodynamic effects of Terlipressin when administered through different methods, including continuous infusion and bolus injection. The research focuses on how this medication impacts various aspects of liver and kidney function in patients with these conditions.

Related diseases and areas:
2
Teropavimab

Diseases, Immune System Diseases, Virus Diseases

Teropavimab is an innovative drug currently being studied in clinical trials for the treatment of HIV-1 infection. This article explores the use of Teropavimab in combination with other medications to potentially provide long-acting treatment options for individuals with HIV-1. The trials aim to evaluate the safety, efficacy, and tolerability of Teropavimab when used alongside other drugs like Lenacapavir and Zinlirvimab in adults with suppressed HIV-1 viral loads.

Related diseases and areas:
- HIV infection
- Acute HIV infection
1
Tertomotide

Diseases, Nervous System Diseases

This article discusses a phase 2 clinical trial investigating the use of Tertomotide (GV1001) in treating mild to moderate Alzheimer’s disease. The study aims to assess the safety and efficacy of this drug when administered subcutaneously over a 52-week period. The trial is designed as a multicenter, randomized, double-blind, placebo-controlled study, focusing on cognitive improvements and overall patient function.

Related diseases and areas:
- Dementia Alzheimer’s type
10
Testosterone

Behavior and Behavior Mechanisms, Diseases, Female Urogenital Diseases and Pregnancy Complications, Hormonal diseases, Male Urogenital Diseases, Neoplasms, Nutritional and Metabolic Diseases, Phenomena and Processes, Physiological processes, Psychiatry and Psychology

Clinical trials involving testosterone therapy are shedding light on new treatment options for various conditions. These studies are investigating different formulations and dosages of testosterone to address issues such as hypogonadism, prostate cancer, and hormone replacement. By examining the safety, efficacy, and effects of testosterone therapy, researchers aim to improve patient outcomes and quality of life.

Related diseases and areas:
4
Testosterone Undecanoate

Cell Physiological Phenomena, Diseases, Hormonal diseases, Nervous System Diseases, Phenomena and Processes

Testosterone Undecanoate has been the subject of numerous clinical trials, investigating its potential benefits in treating various medical conditions. These trials have explored its use in hypogonadism, delayed puberty, non-alcoholic steatohepatitis, female sexual dysfunction, and even in optimizing performance during military operations. The studies have examined different formulations, dosages, and administration methods of Testosterone Undecanoate, providing valuable insights into its efficacy and safety profile.

Related diseases and areas:
8
TETANUS TOXOID

Bacterial Infections and Mycoses, Diseases, Immune system processes, Musculoskeletal Diseases, Phenomena and Processes, Respiratory Tract Diseases

Tetanus Toxoid (TT) is a crucial component in preventing tetanus, a serious disease caused by bacteria that can lead to muscle stiffness and spasms. Clinical trials involving Tetanus Toxoid are important for understanding how this vaccine works, especially when combined with other treatments like Tetanus Immune Globulin (TIG). These studies help researchers determine the most effective ways to protect individuals who have either never been vaccinated against tetanus or whose antibody levels have fallen below protective thresholds. This article explores the research being conducted on Tetanus Toxoid, particularly focusing on how it functions when administered alongside other tetanus-preventing medications.

Related diseases and areas:
2
Tetanus Toxoid Adsorbed On Aluminium Hydroxide, Hydrated And Aluminium Phosphate

Bacterial Infections and Mycoses, Diseases, Nervous System Diseases

This article examines clinical trials involving the use of tetanus toxoid adsorbed on aluminum hydroxide, hydrated and aluminum phosphate in combination vaccines. These trials aim to assess the safety, efficacy, and immune response of tetanus toxoid when administered alongside other vaccine components for protection against multiple diseases.

Related diseases and areas:
- Multiple sclerosis relapse
- Streptococcal infection
3
Tetracaine Hydrochloride

Eye Diseases

Tetracaine Hydrochloride, a local anesthetic, is being studied in several clinical trials for its effectiveness in different medical procedures. These trials aim to evaluate its efficacy, safety, and potential applications in areas such as dental anesthesia, corneal abrasion treatment, and postoperative pain management. The research explores various formulations and combinations of Tetracaine Hydrochloride to optimize its anesthetic properties and minimize side effects.

Related diseases and areas:
- Glaucoma
7
Tetracosactide

Cardiovascular Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Immune System Diseases, Musculoskeletal Diseases, Nervous System Diseases

Tetracosactide, also known as Synacthen or cosyntropin, is a synthetic analogue of adrenocorticotropic hormone (ACTH) used in various clinical trials to assess adrenal function and explore potential therapeutic applications. This article delves into the diverse uses of Tetracosactide in clinical research, ranging from diagnosing adrenal insufficiency to investigating its effects on conditions such as membranous nephropathy and polycystic ovary syndrome.

Related diseases and areas:
3
Tetracycline Hydrochloride

Bacterial Infections and Mycoses, Diseases, Musculoskeletal Diseases, Nutritional and Metabolic Diseases

Tetracycline Hydrochloride, a widely used antibiotic, is being studied in various clinical trials for its potential benefits in treating different medical conditions. These trials aim to explore its effectiveness in preventing and treating infections, managing skin conditions, and even its possible role in cancer treatment. This article summarizes the key findings from recent clinical trials involving Tetracycline Hydrochloride, providing insights into its diverse applications in modern medicine.

Related diseases and areas:
- Type 2 diabetes mellitus
- Osteoporosis
1
Tetrahydrouridine

Diseases, Hemic and Lymphatic Diseases

Tetrahydrouridine (THU) is being studied in various clinical trials as a supportive drug to enhance the effectiveness of other cancer treatments. THU is often combined with drugs like decitabine or cytochlor to improve their absorption and distribution in the body. These trials aim to explore THU’s potential in treating different types of cancer, including lung cancer, blood disorders, and head and neck cancers.

Related diseases and areas:
- Sickle cell disease
1
TETRODOTOXIN

Analytical, Diagnostic and Therapeutic Techniques and Equipment, Anesthesia and Analgesia, Diseases, Nervous System Diseases

Tetrodotoxin (TTX) is a potent neurotoxin currently being studied in clinical trials for its potential to treat various pain conditions, particularly chemotherapy-induced neuropathic pain. This powerful compound, administered as a subcutaneous injection, has shown promise in several clinical studies for providing relief to patients suffering from pain related to cancer treatments. Research is evaluating different formulations, dosages, and administration schedules to determine the optimal therapeutic approach while assessing its safety profile. This article explores the current state of tetrodotoxin research based on recent clinical trials, focusing on its potential benefits for patients experiencing chemotherapy-related nerve pain.
1
TEV-53408

Digestive System Diseases, Diseases

TEV-53408 is an investigational drug currently being studied in clinical trials for the treatment of autoimmune conditions including vitiligo and celiac disease. This medication is administered as a subcutaneous injection and aims to address the underlying immune responses in these conditions. Researchers are evaluating both the safety profile of TEV-53408 and its effectiveness in treating symptoms and improving quality of life for patients. The ongoing trials represent important steps toward potentially developing a new therapeutic option for patients with these challenging conditions.

Related diseases and areas:
- Coeliac disease
1
Teverelix

Diseases, Neoplasms

Teverelix TFA is a gonadotropin-releasing hormone (GnRH) antagonist currently being studied in clinical trials for its potential in treating advanced prostate cancer. This article explores the ongoing research on Teverelix TFA, including its pharmacokinetics, safety, and efficacy in both healthy volunteers and patients with prostate cancer.

Related diseases and areas:
- Prostate cancer
8
Tezacaftor

Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Diseases, Respiratory Tract Diseases

Tezacaftor is a promising drug being studied in clinical trials for the treatment of cystic fibrosis (CF). As part of combination therapies with other CF medications, tezacaftor aims to improve lung function and quality of life for people with specific CF genetic mutations. This article explores the ongoing research into tezacaftor’s effectiveness and safety for CF patients.

Related diseases and areas:
- Cystic fibrosis
15
Tezepelumab

Diseases, Immune System Diseases, Otorhinolaryngologic Diseases, Respiratory Tract Diseases

Tezepelumab is an emerging biologic therapy being studied in clinical trials for the treatment of severe asthma. This article summarizes key findings from recent trials evaluating the efficacy and safety of tezepelumab in patients with inadequately controlled severe asthma. The trials examine outcomes such as asthma exacerbations, lung function, quality of life, and potential effects on the immune system.

Related diseases and areas:
2
Thalidomide

Diseases, Neoplasms, Nervous System Diseases

Thalidomide, once infamous for its teratogenic effects, is now being investigated for its therapeutic potential in various medical conditions. This article explores recent clinical trials using thalidomide to treat a range of disorders, including beta-thalassemia, chronic radiation proctitis, syringomyelia, and hereditary hemorrhagic telangiectasia. These studies aim to evaluate the drug’s efficacy, safety, and potential benefits in managing these challenging conditions.

Related diseases and areas:
1
The-630

Diseases, Neoplasms

A new clinical trial is underway to assess the effectiveness and safety of THE-630, an oral medication designed to treat advanced gastrointestinal stromal tumors (GIST). This study aims to determine the optimal dosage and evaluate the drug’s ability to combat GIST in patients who have not responded well to previous treatments. The trial consists of two phases: a dose escalation phase to establish safety and appropriate dosing, followed by an expansion phase to further examine the drug’s effectiveness in different patient groups.

Related diseases and areas:
- Gastrointestinal stromal tu…
1
Theophylline

Cardiovascular Diseases, Diseases

Theophylline, a medication traditionally used to treat respiratory conditions, is being investigated for its potential benefits in various medical conditions. Clinical trials are exploring its effects on bronchiectasis, syncope, diaphragmatic dysfunction, chronic obstructive pulmonary disease (COPD), and pseudohypoparathyroidism. These studies aim to evaluate theophylline’s efficacy, safety, and potential new applications in different patient populations.

Related diseases and areas:
- Heart disease congenital
1
THEOPHYLLINE ANHYDROUS

Cardiovascular Diseases

THEOPHYLLINE ANHYDROUS has been studied in different clinical trial settings. One trial tested oral theophylline tablets for treating post-dural puncture headache (a severe headache that can happen after spinal anesthesia or an accidental puncture during epidural anesthesia). Another study used intravenous theophylline anhydrous as part of a heart imaging evaluation in people with chronic total coronary artery occlusion (a long-lasting complete blockage of a heart artery). This article explains what these trials looked at, how the drug was given, and what outcomes were measured.

Related diseases and areas:
- Chronic disease
- Coronary artery occlusion
1
Thiamazole

Diseases, Hormonal diseases

Thiamazole, also known as methimazole, is a medication primarily used to treat hyperthyroidism and Graves’ disease. This article explores recent clinical trials investigating the use of thiamazole in various medical conditions, including thyroid disorders and potential applications in other areas like cancer treatment. We’ll examine how researchers are studying its effects, dosing strategies, and potential benefits for patients.

Related diseases and areas:
- Graves’ disease
1
Thiamine

Diseases, Nervous System Diseases

Thiamine, also known as vitamin B1, is being studied in several clinical trials for its potential benefits in various medical conditions. These trials aim to investigate the effects of thiamine supplementation on heart diseases, septic shock, critical illness, and cognitive function. Researchers are exploring how thiamine may improve patient outcomes, cardiac function, oxygen utilization, and overall health in different clinical scenarios.

Related diseases and areas:
- Huntington’s disease
4
Thiamine Hydrochloride

Bacterial Infections and Mycoses, Behavioral Disciplines and Activities, Cardiovascular Diseases, Diseases, Mental Disorders, Musculoskeletal and Neural Physiological Phenomena, Musculoskeletal Diseases, Phenomena and Processes, Psychiatry and Psychology

Thiamine Hydrochloride, also known as Vitamin B1, is being studied in various clinical trials for its potential therapeutic benefits. These trials are investigating the use of thiamine in treating conditions such as Wernicke-Korsakoff syndrome, septic shock, thiamine deficiency, heart failure, and hyperthyroidism. Researchers are exploring different dosages and administration methods to determine the optimal use of thiamine in various medical contexts.

Related diseases and areas:
2
Thiamine Nitrate

Cardiovascular Diseases, Respiratory Tract Diseases

This article explores the use of Thiamine Nitrate, also known as Vitamin B1, in various clinical trials. Researchers are investigating its potential benefits for conditions such as thiamine deficiency, heart failure, hyperthyroidism, and cognitive function in patients undergoing coronary artery bypass grafting. The studies aim to understand how thiamine supplementation may improve patient outcomes and quality of life across different medical scenarios.

Related diseases and areas:
- Critical illness
- Cardiogenic shock
1
Thiamine Nitrate Bp

Cardiovascular Diseases

This article examines the use of Thiamine Nitrate BP, a component of Concavit Capsules, in clinical trials for Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM). While the primary focus of the trial is on eplontersen, Concavit Capsules, which contain Thiamine Nitrate BP among other vitamins, are being used as a supplementary treatment. This study aims to assess the long-term safety and efficacy of the treatment in patients with ATTR-CM.

Related diseases and areas:
- Cardiac amyloidosis
3
Thiocolchicoside

Diseases, Musculoskeletal Diseases

Thiocolchicoside is a muscle relaxant drug that has been the subject of several clinical trials, particularly for its potential in treating various types of pain. These studies have explored its efficacy in conditions such as low back pain, neck pain, and temporomandibular disorders. The trials have investigated different formulations of thiocolchicoside, including oral tablets, injections, and topical applications, often in combination with other pain-relieving medications.

Related diseases and areas:
- Back pain
2
Thiopental Sodium

Analytical, Diagnostic and Therapeutic Techniques and Equipment, Anesthesia and Analgesia, Mental Disorders, Psychiatry and Psychology

Thiopental Sodium, a fast-acting barbiturate anesthetic, has been the subject of several clinical trials exploring its efficacy and effects in various medical procedures. This article summarizes key findings from recent studies comparing Thiopental to other anesthetics, particularly in areas such as induction of anesthesia, effects on fear learning and memory, and its use in specialized procedures like electroconvulsive therapy (ECT) and in vitro fertilization (IVF).

Related diseases and areas:
- Major depression
18
Thiotepa

Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Diseases, Eye Diseases, Hemic and Lymphatic Diseases, Immune System Diseases, Neoplasms, Nervous System Diseases

Thiotepa, an alkylating agent with potent antitumor and immunosuppressive properties, is being extensively studied in clinical trials for its efficacy in various cancer treatments and stem cell transplantation procedures. This article explores the ongoing research on Thiotepa’s use in different medical conditions, its potential benefits, and the challenges associated with its administration.

Related diseases and areas:
3
Threonine

Digestive System Diseases, Diseases, Neoplasms, Nutritional and Metabolic Diseases

This article provides an overview of clinical trials investigating the use of threonine, an essential amino acid, in treating different medical conditions. These trials aim to evaluate the safety and efficacy of threonine-containing medications in patients with pulmonary arterial hypertension, short bowel syndrome, and other disorders. The studies explore various formulations and combinations of threonine with other substances to optimize treatment outcomes.

Related diseases and areas:
1
Thymalfasin

Diseases, Respiratory Tract Diseases

Thymalfasin, also known as thymosin alpha 1, is a synthetic peptide being investigated in clinical trials for its potential therapeutic effects in various medical conditions. This article summarizes key findings from recent clinical trials exploring the use of thymalfasin in diseases such as COVID-19, cancer, HIV, and sepsis. The trials aim to evaluate thymalfasin’s ability to modulate the immune system and potentially improve patient outcomes across different disease states.

Related diseases and areas:
- Cystic fibrosis
1
Thyme Herb Fluid Extract (1:2-2,5), Extracting Agent: Ammonia 10 % : Gycerol 85 % : Ethanol 90 % (V/V) : Water (1 : 20 : 70 : 109)

Respiratory Tract Diseases

This article discusses a clinical trial investigating the use of Thyme Herb Fluid Extract (1:2-2,5) in combination with other herbal extracts for the treatment of acute bronchitis. The study aims to compare the efficacy and safety of three herbal medicinal products in managing this common respiratory condition. The trial focuses on assessing changes in bronchitis symptoms and cough severity over a treatment period of 7 days.

Related diseases and areas:
- Bronchitis
1
Tianeptine

Mental Disorders

This article examines the use of tianeptine, a unique antidepressant medication, in various clinical trials. Tianeptine has shown promise in treating conditions such as major depressive disorder, bipolar disorder, post-mastectomy pain syndrome, and cognitive impairments associated with COVID-19. The trials explore tianeptine’s efficacy compared to other antidepressants and its potential to improve cognitive function and alleviate pain symptoms.
1
Tianeptine Sodium

Diseases, Nervous System Diseases

This article discusses a clinical trial investigating the use of Tianeptine Sodium, an atypical antidepressant, for treating patients with Treatment Resistant Depression (TRD). The study aims to evaluate the effectiveness of Tianeptine in patients who have not responded to previous antidepressant treatments and to explore its unique mechanism of action involving the opioid system.

Related diseases and areas:
- Post-acute COVID-19 syndrome
1
Tiapride

Mental Disorders, Psychiatry and Psychology

This article delves into the use of Tiapride in clinical trials, focusing on its applications in treating various disorders. Tiapride, a neuroleptic medication, has been studied for its potential benefits in conditions such as tic disorders, Huntington’s disease, and gerontopsychiatric disorders. We’ll examine the findings from different clinical trials to provide a comprehensive overview of Tiapride’s efficacy, safety, and potential applications in medical treatment.

Related diseases and areas:
- Psychotic disorder
1
Tiaprofenic Acid

Pathological Conditions, Signs and Symptoms

This article explores the use of Tiaprofenic Acid in clinical trials for treating chronic back pain. Tiaprofenic Acid is being studied as part of a combination therapy to assess its effectiveness and safety in managing long-term back pain. The trials aim to provide valuable insights into potential new treatment options for patients suffering from this common and often debilitating condition.

Related diseases and areas:
- Back pain
25
Ticagrelor

Analytical, Diagnostic and Therapeutic Techniques and Equipment, Cardiovascular Diseases, Diagnosis, Diseases, Nervous System Diseases

Ticagrelor, also known by the brand names Brilinta, Brilique, and Possia, is an antiplatelet medication that has been the subject of numerous clinical trials. These studies aim to evaluate its safety, efficacy, and pharmacokinetics in different patient populations, including those with acute coronary syndrome, renal impairment, and undergoing percutaneous coronary intervention. The trials explore various aspects of Ticagrelor use, such as dosing strategies, administration methods, and comparison with other antiplatelet drugs.

Related diseases and areas:
5
Tiemonium Methylsulphate

Cardiovascular Diseases, Diseases, Hormonal diseases, Musculoskeletal Diseases, Nutritional and Metabolic Diseases

This article discusses the use of Tiemonium Methylsulphate, in combination with Colchicine, in clinical trials for the treatment of calcium pyrophosphate deposition disease (CPPD). The study aims to evaluate the effectiveness of this drug combination in managing inflammation and symptoms associated with CPPD, a condition that affects joints and can cause arthritis-like symptoms.

Related diseases and areas:
1
TIFCEMALIMAB

Diseases, Neoplasms

Tifcemalimab is an investigational immunotherapy drug being studied in clinical trials for small cell lung cancer (SCLC). Current trials are testing tifcemalimab either together with another immunotherapy drug called toripalimab or as part of a combination that also includes chemotherapy and low-dose radiotherapy. These studies are mainly looking at how safe the treatment is and whether it helps people live longer or keeps the cancer from growing for longer.

Related diseases and areas:
- Small cell lung cancer limi…
4
Tigecycline

Analytical, Diagnostic and Therapeutic Techniques and Equipment, Anesthesia and Analgesia, Bacterial Infections and Mycoses, Diseases, Respiratory Tract Diseases

Tigecycline is an antibiotic being studied in clinical trials for treating various bacterial infections. These trials aim to evaluate its safety, effectiveness, and optimal dosing in different patient populations and conditions. Researchers are investigating tigecycline’s potential for treating drug-resistant infections, complicated skin and intra-abdominal infections, and even certain types of leukemia. The trials provide valuable insights into how tigecycline performs in real-world clinical settings.

Related diseases and areas:
1
Tigulixostat

Diseases, Musculoskeletal Diseases, Nutritional and Metabolic Diseases, Pathological Conditions, Signs and Symptoms

Tigulixostat, also known as LC350189, is a new drug being studied in clinical trials for the treatment of gout and hyperuricemia. These trials aim to assess the safety and effectiveness of Tigulixostat in managing serum uric acid levels, reducing gout flares, and addressing tophi in patients with gout. The studies compare Tigulixostat to placebo and existing treatments like allopurinol, exploring various dosages and treatment durations to determine its potential as a new therapeutic option for gout patients.

Related diseases and areas:
- Gout
2
TIL CELLS

Diseases, Neoplasms, Skin and Connective Tissue Diseases

TIL cells (tumor-infiltrating lymphocytes) are immune cells taken from a person’s tumor, grown and prepared in a lab, and then given back by infusion to help the immune system fight cancer. Several clinical trials are studying TIL-based treatments in different cancers, including advanced solid tumors, metastatic melanoma, and stage III/IV ovarian cancer. These studies mainly look at safety (side effects) and how well the treatment may control or shrink tumors.

Related diseases and areas:
- Metastatic malignant melanoma
2
Tildacerfont

Genetic Phenomena, Phenomena and Processes

Tildacerfont, also known as SPR001, is an investigational drug being studied in clinical trials for the treatment of Congenital Adrenal Hyperplasia (CAH) and Polycystic Ovary Syndrome (PCOS). These trials aim to evaluate the safety, efficacy, and potential benefits of Tildacerfont in managing hormone imbalances and reducing the need for high doses of glucocorticoids in patients with these conditions. The studies involve both adults and children, exploring various dosing regimens and treatment durations to determine the optimal use of this promising medication.

Related diseases and areas:
- Adrenogenital syndrome
7
Tildrakizumab

Diseases, Eye Diseases, Immune System Diseases, Skin and Connective Tissue Diseases

This article explores the use of Tildrakizumab, a monoclonal antibody that targets interleukin-23, in various clinical trials. These studies aim to evaluate its effectiveness and safety in treating conditions such as psoriasis, vitiligo, and graft-versus-host disease. The trials assess different aspects of patient outcomes, including disease severity, quality of life, and overall well-being.

Related diseases and areas:
3
Tilmanocept

Analytical, Diagnostic and Therapeutic Techniques and Equipment, Diseases, Investigative Techniques, Neoplasms, Surgical Procedures, Operative

Tilmanocept, also known by its brand name Lymphoseek, is an innovative radiotracer being studied in various clinical trials for its potential in imaging and diagnostic applications. This article explores the use of Tilmanocept in clinical trials for conditions such as rheumatoid arthritis, cancer, and lymph node mapping. We’ll examine how this agent works, its potential benefits, and the ongoing research to evaluate its effectiveness and safety in different medical scenarios.

Related diseases and areas:
1
Tilsotolimod Sodium

Diseases, Neoplasms

A new clinical trial is investigating the potential of Tilsotolimod Sodium (IMO-2125) in treating advanced melanoma. This study focuses on patients with pT3-4 cN0M0 melanoma, examining how intradermal administration of the drug might affect tumor presence in sentinel lymph nodes and impact overall patient outcomes.

Related diseases and areas:
- Malignant melanoma
2
Timbetasin Acetate

Diseases, Eye Diseases

A new clinical trial is investigating the potential of Timbetasin Acetate, a synthetic version of a naturally occurring peptide, in treating Neurotrophic Keratopathy (NK). This eye condition, characterized by decreased corneal sensitivity and persistent epithelial defects, has been challenging to treat effectively. The study aims to evaluate the safety and efficacy of RGN-259, a 0.1% Timbetasin Acetate ophthalmic solution, compared to a placebo in patients with NK.

Related diseases and areas:
- Neurotrophic keratopathy
3
Timolol

Diseases, Eye Diseases, Ocular Physiological Phenomena, Phenomena and Processes

Timolol, a medication primarily known for treating glaucoma, has been the subject of several clinical trials exploring its potential uses in various medical conditions. These trials have investigated timolol’s effectiveness in treating conditions such as infantile hemangiomas, chronic wounds, and even acne and rosacea. The studies have focused on different formulations of timolol, including eye drops, gels, and topical applications, to evaluate its safety, efficacy, and patient satisfaction across different patient populations and medical conditions.

Related diseases and areas:

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