In short
Clinical trials investigating YOHIMBINE HYDROCHLORIDE are looking at how it may affect stress-related behavior and decision-making. The available study involved military personnel and tested whether it changes moral judgment during an acute stress response. The trial focused on study outcomes such as choice patterns and decision-making errors.
Key points
- Only one clinical trial was provided for YOHIMBINE HYDROCHLORIDE. It was a Phase 3 interventional study that was completed and enrolled 100 military personnel. The study looked at how YOHIMBINE HYDROCHLORIDE and related treatments may affect moral judgment during a stress response. Main outcomes included utilitarian, deontological, and compromise choices, as well as rationality violations in decision-making. The trial focused on behavior under stress rather than on a disease treatment.
Trial overview
The clinical trial with YOHIMBINE HYDROCHLORIDE was titled “Understanding the Neurobiology of Pharmacologically-induced Acute Stress on Ethical Decisions” and was listed as completed. It was an interventional study, which means researchers gave study treatments and then measured the effects.
Who participated
The trial was designed to study the effects of yohimbine and/or hydrocortisone on moral judgment in military personnel. The study enrolled 100 people.
What was studied
The study aimed to observe how YOHIMBINE HYDROCHLORIDE and related study treatments affected moral judgment during a situation meant to mimic an acute stress response in humans. In simple terms, the researchers wanted to see whether stress-related treatment changed how people made ethical choices.
The listed interventions were cellulose microcrystalline, YOCORAL 5 mg tabletten, and Hydrocortison Teva 10 mg, all given orally in the trial record. The source data does not provide more detail about how these were compared beyond their listing in the study.
Main outcomes
The primary outcomes focused on the number of utilitarian, deontological, and compromise choices in a behavioral task measuring moral judgment. These are different ways people may decide what to do in a difficult ethical situation.
The trial also measured the number of violations in rationality when making moral decisions. This means the researchers looked for choices that did not follow expected logical patterns in the task.
Study design and phase
This was a Phase 3 trial. Phase 3 studies are later-stage trials that usually test how well an intervention works in a larger group of people.
The study was completed, so the planned research activities were finished. The available data does not include results, so this article focuses on what the trial planned to measure rather than on final findings.
What the study tracked
The trial tracked how people responded in a moral decision task under a stress-like condition. The key idea was to see whether study treatment changed the balance between rule-based decisions, outcome-based decisions, and middle-ground choices.
Because the source data is limited to one study, the clinical trial picture for YOHIMBINE HYDROCHLORIDE is narrow and specific. It centers on stress, ethics, and decision-making in military personnel rather than on a broad range of diseases.