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Sodium Phosphate Dodecahydrate

This article discusses the use of Sodium Phosphate Dodecahydrate in clinical trials for treating childhood asthma. While the primary focus of the study is on azithromycin, Sodium Phosphate Dodecahydrate is included as part of the trial. The research aims to explore new treatment options for children aged 1-5 years who are hospitalized due to asthma-like symptoms.

Table of Contents

What is Sodium Phosphate Dodecahydrate?

Sodium Phosphate Dodecahydrate is a chemical compound that is being studied for its potential medical applications. It is a form of sodium phosphate that contains twelve water molecules, hence the term “dodecahydrate” in its name[1].

Medical Uses

While the specific medical uses of Sodium Phosphate Dodecahydrate are still being investigated, it is often used in pharmaceutical formulations. In the context of the clinical trial data provided, it is being studied as part of a placebo formulation in a trial related to childhood asthma[1].

It’s important to note that in this trial, Sodium Phosphate Dodecahydrate is not the active treatment being tested. Instead, it is part of the placebo, which is a substance that looks like the real treatment but doesn’t contain the active drug. Placebos are crucial in clinical trials to help researchers determine the true effects of the drug being studied[1].

Administration

According to the clinical trial information, Sodium Phosphate Dodecahydrate is being administered as an oral solution. This means it’s a liquid that is taken by mouth[1].

Current Clinical Trials

The clinical trial mentioned in the data is studying the use of azithromycin (an antibiotic) for treating hospitalized children aged 1-5 years with asthma symptoms. In this study, Sodium Phosphate Dodecahydrate is part of the placebo formulation[1].

The main objectives of this trial are:

  • To investigate the effect of a three-day azithromycin treatment versus placebo in children hospitalized due to asthma-like symptoms[1].
  • To examine individual responses to treatment, potentially contributing to personalized treatment approaches in the future[1].
  • To increase understanding of how bacteria influence asthma-like episodes in preschool children[1].

Precautions and Side Effects

As Sodium Phosphate Dodecahydrate is part of a placebo formulation in this trial, specific side effects related to this compound are not discussed in the provided data. However, it’s always important to inform your healthcare provider about any medications or supplements you’re taking, including those in clinical trials[1].

If you’re participating in a clinical trial or considering doing so, always discuss potential risks and benefits with your healthcare provider and the research team. They can provide you with the most up-to-date and relevant information for your specific situation[1].

Aspect Details
Study Type Therapeutic exploratory (Phase II)
Primary Drug Azithromycin
Secondary Drug Sodium Phosphate Dodecahydrate
Target Condition Childhood asthma
Age Group 1-5 years (12-71 months)
Primary Objective Investigate effect of three-day azithromycin treatment vs. placebo
Secondary Objectives Examine individual treatment response, contribute to personalized treatment
Study Design Double-blind, randomized, controlled study
Primary Endpoint Duration of asthma-like episode from start of randomization

FAQ

  • What is the main purpose of the clinical trial involving Sodium Phosphate Dodecahydrate? The main purpose of the trial is to investigate the effect of azithromycin treatment in children aged 1-5 years who are hospitalized due to asthma-like symptoms. Sodium Phosphate Dodecahydrate is included as part of the study, though its specific role is not detailed in the provided information.
  • What age group is the trial focusing on? The trial is focusing on children aged 12-71 months old (1-5 years).
  • What are some of the inclusion criteria for the trial? Some inclusion criteria are: previous episodes of asthma-like symptoms, current medical treatment with specific asthma medications, parent/guardian agreement to admit the child and follow trial procedures, and fluent Danish language skills of parents/guardians.
  • What are some of the exclusion criteria for the trial? Some exclusion criteria include: known allergy to macrolide antibiotics, impaired liver or kidney function, neurological or psychiatric diseases, congenital or acquired QT interval issues, severe heart conditions, and clinical signs of pneumonia.
  • What are some of the secondary objectives of the study? Secondary objectives include examining individual response to treatment, potentially contributing to personalized treatment based on the child's respiratory microbiome and/or immunological profile, and increasing understanding of the influence of bacteria on asthma-like episodes in preschool children.

Ongoing Clinical Trials on Sodium Phosphate Dodecahydrate

  • Study on Azithromycin for Treating Hospitalized Children Aged 1-5 with Asthma Symptoms

    Recruiting

    1 1
    Investigated diseases:
    Investigated drugs:
    Denmark

Glossary

  • Asthma: A chronic lung condition characterized by inflammation and narrowing of the airways, leading to breathing difficulties.
  • Sodium Phosphate Dodecahydrate: A chemical compound used in the clinical trial, though its specific role in asthma treatment is not detailed in the provided information.
  • Azithromycin: An antibiotic medication being studied for its potential effects on asthma symptoms in children.
  • SABA: Short-Acting Beta Agonists, a type of medication used for quick relief of asthma symptoms.
  • ICS: Inhaled Corticosteroids, a type of medication used for long-term control of asthma symptoms.
  • LTRA: Leukotriene Receptor Antagonists, another type of medication used for long-term asthma control.
  • QT interval: A measurement on an electrocardiogram that represents the time it takes for the heart's electrical system to recharge between beats.
  • Ergotism: A condition caused by ergot poisoning, which can occur as a side effect of certain medications.
  • Respiratory microbiome: The community of microorganisms living in the respiratory tract.
  • Immunological profile: A detailed analysis of an individual's immune system components and function.

References

  1. http://clinicaltrials.eu/trial/study-on-azithromycin-for-treating-hospitalized-children-aged-1-5-with-asthma-symptoms/