In short
Clinical trials investigating Liquid Paraffin in the provided data focus on a moisturizer study in children with atopic dermatitis, also called eczema. The trial looks at whether a study cream can help prevent relapse, meaning the return of eczema symptoms, compared with a reference cream. It mainly involves children and their parents or legal guardians.
Key points
- Clinical trial data on Liquid Paraffin here focus on a Phase 3 study in children with atopic dermatitis, also called eczema. The study tests whether a newly developed moisturizer can prevent eczema relapse better than a reference cream. The main outcome is relapse, measured over time with a hazard ratio. The trial is interventional, meaning treatment was given and then outcomes were measured. Parents or legal guardians helped report relapse events, and the study enrolled 270 participants.
Trial overview
The available clinical trial data for Liquid Paraffin describe one interventional study in children with atopic dermatitis, also called eczema. The study asked whether a newly developed moisturizer could help prevent relapse of eczema compared with a reference cream.
Condition and population studied
The condition studied was atopic dermatitis/eczema, a common skin problem that can come and go over time. The target population was children, and the study also involved their parents or legal guardians because they helped report when relapse happened.
Study design and phase
This was an interventional study, which means the researchers gave a treatment and then measured the results. The trial was in Phase 3, which is a later stage of research used to test how well a treatment works in a larger group of people. The study enrolled 270 participants and was completed.
What the trial measured
The main outcome was relapse of atopic eczema, measured as a hazard ratio. In simple terms, relapse means the eczema returned and treatment for the study skin area had to be increased. The date of relapse was recorded in an eDiary and then confirmed by the investigator.
Study products compared
The trial summary says the study compared a newly developed moisturizer with a reference cream to see which one better prevented relapse. The listed topical products in the trial record were Essex, Advantan® 0,1% Creme, Linola Fett, ECURAL ® Fettcreme, and Miniderm Duo 20 mg/g + 200 mg/g kräm. The data provided do not give more detail about how each product was used beyond being topical, meaning applied to the skin.
What the available data show
From the provided trial record, the key research question was whether a moisturizer could help prevent eczema relapse in children better than a comparison cream. The study was completed, but no detailed results are included in the source data provided here.