In short
This article discusses clinical trials investigating the use of Felis Domesticus (555), a cat hair allergen extract, in allergy testing. While the primary focus of these trials is on other allergens like birch and grass pollen, Felis Domesticus (555) is included as a reference allergen for skin prick tests. These studies aim to assess the effectiveness and safety of sublingual immunotherapy for various allergies, providing valuable insights into allergy diagnosis and treatment methods.
At a glance
- Study Type
- Phase II-III clinical trials
- Main Allergens Studied
- Birch pollen (Betula verrucosa), Grass pollen (Phleum pratense)
- Role of Felis Domesticus (555)
- Reference allergen in skin prick tests
- Primary Objective
- Assess efficacy and safety of sublingual immunotherapy
- Key Inclusion Criteria
- Adults 18-65, moderate to severe allergic rhinitis, positive skin prick test
- Primary Endpoint
- Differences in Combined Symptom and Medication Score (CSMS)
- Secondary Endpoints
- Quality of life, symptom-free days, nasal provocation test results
What is FELIS DOMESTICUS (555)?
FELIS DOMESTICUS (555), also known as "555 Cat Hair," is a medical product used in allergy testing and treatment. It is derived from cat hair and contains allergens that can trigger allergic reactions in sensitive individuals. This substance is classified as a structurally diverse substance - allergen, which means it's a complex mixture of proteins and other molecules found in cat hair that can cause allergic responses.
Medical Uses
The primary use of FELIS DOMESTICUS (555) is in the diagnosis and management of cat allergies. It is specifically formulated as a solution for skin-prick tests, which are commonly used to identify allergies. During a skin-prick test, a small amount of this solution is applied to the skin to see if it triggers an allergic reaction, helping doctors diagnose cat allergies.
While not explicitly mentioned in the provided clinical trial data, allergen extracts like FELIS DOMESTICUS (555) can also be used in immunotherapy treatments. These treatments aim to reduce sensitivity to specific allergens over time, potentially alleviating allergy symptoms.
Administration
FELIS DOMESTICUS (555) is administered topically during skin-prick tests. The typical dosage is 1 drop, with a maximum daily and total dose of 1 drop. It's important to note that this product should only be administered by healthcare professionals trained in allergy testing procedures.
Clinical Trials
While the provided clinical trial data doesn't specifically focus on FELIS DOMESTICUS (555), it does mention this substance in the context of other allergy studies. This suggests that similar methodologies and considerations might apply to cat allergy research. Some key points from related allergy trials include:
- Trials often focus on patients with moderate-to-severe allergic rhinitis or rhinoconjunctivitis.
- Researchers use various methods to confirm allergies, including skin prick tests, blood tests for specific IgE antibodies, and nasal provocation tests.
- Studies typically exclude patients who have had previous immunotherapy for the specific allergen being studied.
- Researchers often assess the effectiveness of treatments by measuring symptom scores and medication use during allergy seasons.
Potential Side Effects
As FELIS DOMESTICUS (555) is used in diagnostic tests, the risk of severe side effects is generally low when used as directed. However, as with any allergy test, there is a potential for allergic reactions. These may include:
- Local skin reactions at the test site (redness, itching, swelling)
- In rare cases, more severe allergic reactions
It's crucial to inform your healthcare provider of any adverse reactions during or after the test.
Precautions
Based on information from similar allergy studies, several precautions should be considered when using FELIS DOMESTICUS (555):
- Inform your doctor if you have a history of severe allergic reactions.
- The test may not be suitable for patients with certain skin conditions or those taking medications that could interfere with the results.
- Patients with severe or uncontrolled asthma may need special consideration before undergoing allergy testing.
- Pregnant or breastfeeding women should consult their doctor before undergoing allergy tests.
Always follow your healthcare provider's instructions and report any concerns or unusual symptoms during or after the allergy test.