In short
This article discusses the use of Cimetidine Hydrochloride in clinical trials for treating advanced or metastatic non-small cell lung cancer (NSCLC). The drug is being studied as part of a combination therapy with other medications to evaluate its safety, effectiveness, and potential benefits for patients with this serious condition.
At a glance
- Study Type
- Phase II clinical trial
- Target Condition
- Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)
- Treatment
- Cimetidine Hydrochloride in combination with other drugs
- Primary Objectives
- Evaluate safety, tolerability, and objective response rate (ORR)
- Secondary Objectives
- Assess duration of response, progression-free survival, overall survival, pharmacokinetics, and immunogenicity
- Eligibility
- Adults (18+) with confirmed advanced NSCLC, meeting specific health criteria
- Study Design
- Screening period, treatment period, and survival follow-up period
- Treatment Duration
- Until discontinuation criteria are met
What is Cimetidine Hydrochloride?
Cimetidine Hydrochloride is an active substance used in medications. It belongs to a class of drugs known as histamine-2 (H2) blockers. These medications work by reducing the amount of acid produced in the stomach.
Medical Uses
While the specific medical uses are not explicitly stated in the provided information, Cimetidine Hydrochloride is typically used to treat various conditions related to excess stomach acid, such as:
- Gastroesophageal reflux disease (GERD): A condition where stomach acid frequently flows back into the esophagus
- Peptic ulcers: Sores that develop on the lining of the stomach or small intestine
- Zollinger-Ellison syndrome: A rare condition that causes tumors in the pancreas or duodenum, leading to increased stomach acid production
- Heartburn: A burning sensation in the chest caused by stomach acid
It's important to note that the exact use may vary depending on the specific formulation and prescription.
Administration
The information provided does not specify the exact route of administration for this particular formulation of Cimetidine Hydrochloride. However, it's listed as "UNKNOWN USE" in the data. Typically, Cimetidine is available in various forms, including:
- Oral tablets
- Oral liquid
- Injectable solutions
The specific form and method of administration should be determined by your healthcare provider based on your individual needs and condition.
Dosage
The dosage information for this specific formulation is not provided in the given data. The dosage can vary depending on several factors, including:
- The condition being treated
- The severity of the condition
- The patient's age and overall health
- Other medications the patient may be taking
It's crucial to follow the dosage instructions provided by your healthcare provider or as indicated on the prescription label.
Duration of Treatment
The data indicates a maximum treatment period of 75 days for this formulation of Cimetidine Hydrochloride. However, the actual duration of treatment may vary depending on your specific condition and response to the medication. Always follow your healthcare provider's instructions regarding the length of treatment.
Important Considerations
When taking Cimetidine Hydrochloride, keep the following points in mind:
- Pediatric use: The data indicates that this is not a pediatric formulation. Always consult with a pediatrician before giving this medication to children.
- Interactions: Cimetidine can interact with other medications. Inform your healthcare provider about all the medicines you're taking, including over-the-counter drugs and supplements.
- Side effects: Like all medications, Cimetidine can cause side effects. Common side effects may include headache, dizziness, and diarrhea. Consult your healthcare provider if you experience any unusual or severe side effects.
- Regular monitoring: Your healthcare provider may want to monitor your progress regularly to ensure the medication is working effectively and safely.
Remember, this information is general, and your specific treatment plan may differ. Always consult with your healthcare provider for personalized medical advice and follow their instructions carefully.