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YOHIMBINE HYDROCHLORIDE

Clinical trials investigating YOHIMBINE HYDROCHLORIDE are looking at how it may affect stress-related behavior and decision-making. The available study involved military personnel and tested whether it changes moral judgment during an acute stress response. The trial focused on study outcomes such as choice patterns and decision-making errors.

Table of Contents

Trial overview

The clinical trial with YOHIMBINE HYDROCHLORIDE was titled “Understanding the Neurobiology of Pharmacologically-induced Acute Stress on Ethical Decisions” and was listed as completed.[1] It was an interventional study, which means researchers gave study treatments and then measured the effects.[1]

Who participated

The trial was designed to study the effects of yohimbine and/or hydrocortisone on moral judgment in military personnel.[1] The study enrolled 100 people.[1]

What was studied

The study aimed to observe how YOHIMBINE HYDROCHLORIDE and related study treatments affected moral judgment during a situation meant to mimic an acute stress response in humans.[1] In simple terms, the researchers wanted to see whether stress-related treatment changed how people made ethical choices.[1]

The listed interventions were cellulose microcrystalline, YOCORAL 5 mg tabletten, and Hydrocortison Teva 10 mg, all given orally in the trial record.[1] The source data does not provide more detail about how these were compared beyond their listing in the study.[1]

Main outcomes

The primary outcomes focused on the number of utilitarian, deontological, and compromise choices in a behavioral task measuring moral judgment.[1] These are different ways people may decide what to do in a difficult ethical situation.[1]

The trial also measured the number of violations in rationality when making moral decisions.[1] This means the researchers looked for choices that did not follow expected logical patterns in the task.[1]

Study design and phase

This was a Phase 3 trial.[1] Phase 3 studies are later-stage trials that usually test how well an intervention works in a larger group of people.[1]

The study was completed, so the planned research activities were finished.[1] The available data does not include results, so this article focuses on what the trial planned to measure rather than on final findings.[1]

What the study tracked

The trial tracked how people responded in a moral decision task under a stress-like condition.[1] The key idea was to see whether study treatment changed the balance between rule-based decisions, outcome-based decisions, and middle-ground choices.[1]

Because the source data is limited to one study, the clinical trial picture for YOHIMBINE HYDROCHLORIDE is narrow and specific.[1] It centers on stress, ethics, and decision-making in military personnel rather than on a broad range of diseases.[1]

Trial ID Phase Condition Studied Status Enrollment
2023-508731-31-01 Phase 3 Mimic an acute stress response in humans Completed 100

FAQ

  • What are clinical trials of YOHIMBINE HYDROCHLORIDE studying? The trial studied how YOHIMBINE HYDROCHLORIDE may affect moral judgment during an acute stress response. It measured the kinds of choices people made in a behavioral task.
  • Who took part in the trial? The study was designed for military personnel. The trial enrolled 100 participants.
  • What phase was the YOHIMBINE HYDROCHLORIDE trial? The study was a Phase 3 trial. Phase 3 trials usually look at how well a treatment works in a larger group of people.
  • What outcomes did the trial measure? The main outcomes were the number of utilitarian, deontological, and compromise choices in a moral judgment task. It also measured the number of violations in rationality when making moral decisions.
  • What was the status of the trial? The trial is listed as Completed. This means the planned study activities were finished.

Ongoing Clinical Trials on YOHIMBINE HYDROCHLORIDE

  • Study on the Effects of Yohimbine and Hydrocortisone on Stress and Moral Decisions in Military Personnel

    Not recruiting

    3 1 1
    Investigated diseases:
    Investigated drugs:
    The Netherlands

Glossary

  • Acute stress response: A short-term body and brain reaction to stress. In this study, the trial tried to mimic that response in humans.
  • Behavioral task: A structured activity used in research to observe how people think, choose, or act.
  • Moral judgment: The process of deciding what is right or wrong in a situation.
  • Utilitarian choice: A decision that aims to create the greatest overall benefit or least harm.
  • Deontological choice: A decision based on rules or duties, even if the outcome is less helpful overall.
  • Compromise choice: A middle-ground decision that is not fully rule-based or fully outcome-based.
  • Rationality violations: Choices that do not follow expected logical patterns in the study task.
  • Interventional study: A study where researchers give a treatment or intervention and then measure the effects.
  • Phase 3: A later-stage clinical trial that usually tests how well a treatment works in a larger group.
  • Enrollment: The number of people who joined the study.

References