Clinical Trials for Osteotomy
This article provides information about ongoing clinical trials related to osteotomy procedures. Currently, there is 1 active trial investigating pain management methods for patients undergoing periacetabular osteotomy, a type of hip surgery. The trial is testing a nerve block technique to improve pain relief and recovery after this surgical procedure.
Clinical trial locations
Study on Ropivacaine Hydrochloride for Reducing Pain After Hip Surgery in Patients Undergoing Periacetabular Osteotomy
This clinical trial is investigating a specialized pain relief method for patients who need periacetabular osteotomy, a surgical procedure to correct hip problems. The study focuses on testing whether a technique called the pericapsular nerve group (PENG) block can effectively reduce pain after surgery better than a placebo.
Main focus: The trial aims to determine how well the PENG block manages pain and prevents complications in the first 24 hours following hip surgery. Researchers will compare outcomes between patients who receive the actual nerve block and those who receive a placebo injection.
Investigational treatment: The study uses Ropivacaine Hydrochloride, a local anesthetic medication that numbs specific body areas. During the PENG block procedure, this medication is injected near the nerves around the hip to provide pain relief after surgery. Some participants will receive Ropivacaine while others will receive saline (saltwater) as a placebo for comparison.
Who can participate: Patients eligible for this trial must meet several criteria:
- Be at least 18 years old
- Be scheduled for periacetabular osteotomy under general anesthesia
- Have an American Society of Anesthesiologists physical status classification of I to III, meaning they range from healthy to having moderate health issues
- Be able to read and understand Danish
- Provide informed consent after understanding the study details
Who cannot participate: The trial excludes certain individuals:
- Patients not undergoing periacetabular osteotomy
- Those outside the specified age range
- Vulnerable populations who cannot provide proper consent
- Patients who do not meet other specific health criteria established by the study
What happens during the study: Participants will undergo their scheduled hip surgery under general anesthesia. During the procedure, they will receive either the PENG block with Ropivacaine or a placebo injection. After surgery, medical staff will carefully monitor pain levels using a scale from 0 to 10, starting in the recovery area and continuing for 24 hours. The study also tracks how much pain medication patients need during this period.
About the condition: Periacetabular osteotomy is performed to treat hip dysplasia, a condition where the hip socket doesn’t properly cover the ball of the thigh bone. This misalignment can cause joint instability and accelerated wear. The surgery involves cutting and repositioning bones around the hip socket to improve coverage and stability, which can reduce pain and improve function over time. This procedure is typically offered to younger adults to prevent arthritis progression.
Summary
Currently, there is one active clinical trial investigating pain management for patients undergoing periacetabular osteotomy. This trial is being conducted in Denmark and focuses on testing the effectiveness of the PENG block using Ropivacaine Hydrochloride as a method to improve post-surgical pain control. The study represents an important effort to enhance recovery experiences for patients undergoing this complex hip surgery. Patients interested in participating should discuss eligibility with their healthcare provider and ensure they meet the language and health requirements specified in the trial criteria.
