In short
Currently, there is 1 ongoing clinical trial for hepatic neoplasm, a condition involving abnormal growths in the liver. This trial is investigating whether lidocaine, a local anesthetic given through an IV, can improve recovery after liver tumor surgery. The study is being conducted in Sweden and focuses on patients undergoing minor liver surgery.
Clinical trial locations
Study on Lidocaine and Sodium Chloride for Patients Undergoing Liver Tumor Surgery
This clinical trial is exploring whether lidocaine can help patients recover better after surgery to remove liver tumors. Lidocaine is a medication commonly used as a local anesthetic, but in this study it is being given through an IV during surgery to see if it helps reduce pain and speed up recovery afterward.
Who can participate:
- Adults who are 18 years or older
- Patients scheduled for minor liver surgery (a type of operation that removes a smaller portion of the liver)
- Those who can provide written informed consent, meaning they understand the study and agree to take part
Who cannot participate:
Patients who have already had surgery to remove liver tumors are not eligible for this trial.
What the trial involves:
Participants will receive either lidocaine or a placebo (an inactive substance that looks like the medication) through an IV during their surgery. The research team will monitor several aspects of recovery including how much pain medication is needed in the first 24 to 48 hours after surgery, how severe the pain is, and whether any complications occur. They will also track when normal bowel movements resume, any nausea or vomiting, and the total length of hospital stay.
Blood samples will be taken at specific times during and after surgery to measure the concentration of lidocaine in the bloodstream. This helps researchers understand how the medication works in the body and whether it affects recovery.
Study medication:
The investigational drug in this trial is lidocaine, which is administered intravenously. Lidocaine works by blocking sodium channels in nerve cells, which helps reduce pain and stabilize nerve activity. In this study, researchers are testing whether it can improve recovery outcomes for patients undergoing liver surgery. Sodium chloride, commonly known as saline, is also used as part of the treatment process.
The trial aims to gather comprehensive data to determine whether lidocaine can be a beneficial addition to the recovery process for patients having liver surgery, and to assess any potential side effects or adverse events.
Summary
There is currently one clinical trial available for patients with hepatic neoplasm who are undergoing liver tumor surgery. This trial is being conducted in Sweden and focuses on evaluating the effectiveness of lidocaine in improving post-surgical recovery. The study specifically targets patients scheduled for minor liver surgery and aims to determine whether intravenous lidocaine can reduce pain, decrease the need for opioid medications, and improve overall recovery outcomes. The trial is exploring an innovative use of a well-known medication to potentially enhance patient care following liver surgery.
