Ongoing Clinical Trials for Hand Fracture
There is currently 1 ongoing clinical trial investigating treatment options for patients undergoing hand surgery related to hand fractures. This trial is exploring improved pain management through the use of specific local anesthetic combinations during surgery.
Clinical trial locations
Study on Lidocaine, Ropivacaine, and Epinephrine for Patients Undergoing Hand Surgery with Ultrasound-Guided Nerve Block
This clinical trial is being conducted in Denmark and focuses on improving pain management for patients undergoing hand surgery, particularly those with forearm fractures or thumb joint procedures. The study investigates a specific type of anesthesia called the lateral infraclavicular plexus brachialis block, which is used to numb the surgical area.
Main inclusion criteria:
- Adults aged 18 years and older
- Patients scheduled for hand surgery due to a broken forearm bone or a procedure to replace or repair the joint at the base of the thumb
- Both men and women are eligible to participate
Main exclusion criteria:
- Patients not undergoing hand surgery for forearm fractures or thumb base joint replacement
- Individuals outside the specified age range
- People who are part of vulnerable populations requiring special protection or care
Focus and goal of the trial:
The primary goal of this study is to understand how two different local anesthetics work together when used for hand surgery. The trial compares the effects of combining ropivacaine, a long-acting anesthetic, with lidocaine, a short-acting anesthetic. Researchers want to determine how quickly these medications start working and how long their pain-relieving effects last. The study will measure the time it takes for pain to return after the anesthesia is given, as well as how long the numbness and inability to move the affected area persist. The anesthetic solution is injected near the nerves that control sensation and movement in the arm using ultrasound guidance. The research aims to improve the effectiveness of anesthesia for hand surgeries, potentially leading to better pain management and recovery for patients.
Investigational drugs:
The trial uses two main local anesthetics. Lidocaine is a medication that numbs a specific area of the body by blocking nerve signals. It works quickly to provide pain relief during surgery. At the molecular level, lidocaine blocks sodium channels in nerve cells, preventing the transmission of pain signals. Ropivacaine is another local anesthetic that provides longer-lasting pain relief. It works in a similar way to lidocaine by blocking sodium channels in nerve cells, but its numbing effect lasts longer. The study investigates how these two medications work together to provide optimal pain control during and after hand surgery.
Summary
Currently, there is one active clinical trial focused on improving anesthesia techniques for patients undergoing hand surgery related to fractures. This trial is taking place in Denmark and is exploring the combination of two local anesthetics to optimize pain management during and after surgical procedures. The study specifically targets patients with forearm fractures or those requiring thumb joint procedures. The research focuses on understanding the timing and duration of pain relief when using a combination of short-acting and long-acting local anesthetics, which could lead to improved surgical outcomes and patient comfort.