Ongoing Clinical Trials for Functional Gastrointestinal Disorder
There is currently 1 ongoing clinical trial investigating treatment options for functional gastrointestinal disorder, a condition causing chronic or recurrent digestive symptoms such as abdominal pain, bloating, and discomfort. The trial is testing a natural combination treatment of peppermint oil and caraway oil to help relieve these symptoms and improve quality of life for patients.
Clinical trial locations
- Germany
Study on Peppermint Oil and Caraway Oil for Patients with Functional Gastrointestinal Disorders
This clinical trial is investigating the effects of Menthacarin, a natural treatment combining peppermint oil and caraway oil, for people experiencing functional gastrointestinal disorders. These disorders can cause uncomfortable symptoms including abdominal pain, bloating, cramping, and a feeling of fullness after eating.
Who can participate:
- Adults aged 18 years or older
- People who have experienced at least one digestive symptom (abdominal pain, cramping, or bloating) at least once per week for 3 months or longer
- Those with moderate to severe symptoms, rated at least 4 out of 10 in intensity
- Participants must be willing to attend all scheduled visits and follow the trial procedures
- Written informed consent is required before joining
Who cannot participate:
- People with other serious health conditions that could interfere with the study
- Those currently participating in another clinical trial
- Individuals who have had recent surgery or are planning surgery during the study period
- Pregnant or breastfeeding women
- People with known allergies to the study medication or its ingredients
- Those with a history of drug or alcohol abuse
- Individuals with uncontrolled mental health disorders
- People taking medications that could interfere with the study treatment
- Those with severe gastrointestinal diseases beyond functional disorders
What the trial involves:
The main focus of this trial is to assess how well Menthacarin can relieve digestive symptoms and improve patients’ quality of life. The treatment comes in special capsules designed to resist stomach acid, allowing the oils to reach the intestines where they can work most effectively. The peppermint and caraway oils are believed to help by relaxing the muscles in the stomach and intestines.
Participants will take the medication over a period of time and monitor their symptoms using simple rating scales. They will track changes in abdominal pain, bloating, cramping, and fullness after eating. The study also examines how the treatment affects bowel movement patterns, including frequency and consistency using the Bristol Stool Scale. Additionally, researchers will measure how the medication influences gut permeability, which refers to how easily substances can pass through the gut lining.
Throughout the trial, participants attend scheduled visits where they discuss symptom changes, medication tolerability, and overall satisfaction with the treatment. Blood samples may be collected to measure specific markers related to gut health. At the end of the study, participants provide feedback on the treatment’s effectiveness and complete quality of life questionnaires.
Investigational drug: Menthacarin is the medication being tested in this trial. It is a combination of two natural oils that have been traditionally used for digestive support. The treatment is administered orally as gastro-resistant soft capsules, which protect the active ingredients from stomach acid so they can reach the intestines intact.
Summary
Currently, there is one active clinical trial investigating treatment options for functional gastrointestinal disorder. The trial is being conducted in Germany and focuses on a natural, plant-based approach using a combination of peppermint oil and caraway oil. This study represents an important effort to find effective treatments for a condition that can significantly impact daily life and wellbeing. The trial takes a comprehensive approach by not only measuring symptom relief but also examining quality of life improvements and the underlying mechanisms of how the treatment affects gut function. Patients interested in participating should meet specific symptom criteria and be prepared to commit to regular monitoring and follow-up visits throughout the study period.
