In short
Currently, there is 1 ongoing clinical trial focused on benign renal neoplasm. This trial is investigating pain management strategies to improve recovery after robot-assisted surgery for conditions affecting the kidneys and ureters, including benign kidney tumors.
Clinical trial locations
Study on Spinal Morphine, Intravenous Lidocaine, and Bupivacaine for Patients Undergoing Robot-Assisted Surgery for Kidney or Ureter Conditions
This trial is exploring different pain management approaches for patients undergoing robot-assisted surgery on the upper urinary tract, which includes the kidneys and ureters. The study is designed to help patients with various conditions including benign kidney tumors, as well as kidney cancer, ureter cancer, kidney stones, and kidney reflux.
Who can participate:
- Adults who are scheduled for planned (non-emergency) robot-assisted surgery on the upper urinary tract
- Both men and women of adult age
- Patients who can provide both spoken and written informed consent after receiving information about the study
Who cannot participate:
- Patients with cancer or tumors in the kidney or ureter (the tube that carries urine from the kidney to the bladder)
- Patients with kidney stones (hard mineral deposits that form inside the kidneys)
- Patients with renal reflux (a condition where urine flows backward from the bladder to the kidneys)
What the trial is studying:
The main goal of this study is to determine whether different pain management strategies can improve recovery after surgery. Researchers are comparing three approaches: spinal morphine (a strong pain reliever injected into the spinal fluid), intravenous lidocaine (a local anesthetic given through a vein), and a combination of bupivacaine (another local anesthetic) with adrenaline. The trial uses a patient-centered measurement called "Quality of Recovery 15" to assess how well patients recover. Participants will be randomly assigned to one of the treatment groups without knowing which treatment they receive, and their recovery will be monitored at multiple time points after surgery, including pain levels and overall well-being.
Investigational drugs being tested:
- Morphine: A strong pain reliever administered into the space around the spinal cord to help reduce pain and improve recovery after surgery
- Lidocaine: A local anesthetic given intravenously to help manage pain and improve recovery by blocking nerve signals
- Bupivacaine: A medication used to numb specific areas of the body, administered as part of spinal pain relief to improve post-surgical recovery
Summary
Currently, only one clinical trial is actively recruiting patients with benign kidney tumors. This trial, located in Sweden, is not specifically focused on treating the tumor itself, but rather on improving the surgical experience and recovery process for patients undergoing robot-assisted surgery. The study compares different pain management strategies using well-established medications—morphine, lidocaine, and bupivacaine—to determine which approach provides the best recovery outcomes. The trial is expected to conclude by the end of 2025, and its findings may help improve post-operative care for patients undergoing similar procedures in the future.
