Groundbreaking research focusing on blood cancers and related disorders, including studies of innovative treatments for Acute Myeloid Leukemia, Multiple Myeloma, and Chronic Myeloid Leukemia.

Novel therapy combinations for AML patients ineligible for intensive chemotherapy
Advanced treatments for relapsed/refractory multiple myeloma
Targeted therapies for chronic phase CML

Investigations include evaluation of new drug combinations and targeted therapies aimed at improving patient outcomes.

02 Gastrointestinal Disorders

Clinical research targeting inflammatory bowel conditions, with studies evaluating new therapeutic approaches for Ulcerative Colitis and Crohn's Disease.

Novel treatments for moderate to severe ulcerative colitis
Advanced therapies for Crohn's disease management
Innovative approaches to gastrointestinal inflammation

Focus on developing treatments for patients who haven't responded adequately to conventional therapies.

03 Respiratory Medicine

Important studies in respiratory conditions, including research on idiopathic pulmonary fibrosis and severe viral lung infections.

Treatments for lung fibrosis
Management of severe viral lung infections
Post-transplant lung complications

Research aims to improve treatment outcomes and quality of life for patients with severe respiratory conditions.

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Clinical trials in Yvoir – page 2

192 trials in Yvoir

Neoplasm malignant

Study on the Long-term Safety and Efficacy of Pembrolizumab and Lenvatinib for Patients with Advanced Tumors

Small cell lung cancer extensive stage

Phase 3 Study of Subcutaneous vs Intravenous Tarlatamab with Siltuximab in Relapsed Extensive-Stage Small Cell Lung Cancer after Platinum Chemotherapy

Idiopathic pulmonary fibrosis

Efficacy and Safety of Oral PIPE-791 in Adults with Idiopathic Pulmonary Fibrosis: A Phase 2 Randomized, Double‑Blind, Placebo‑Controlled Study

Systemic scleroderma

A double‑blind, placebo‑controlled trial of oral BI 1015550 in patients with systemic sclerosis

Chronic obstructive pulmonary disease

Efficacy and safety of lunsekimig in adults with inadequately controlled eosinophilic COPD: a randomized, double‑blind, placebo‑controlled trial

Colorectal cancer

Study of telisotuzumab adizutecan plus drug combination in adults with refractory metastatic colorectal cancer

Pancreatic carcinoma metastatic

Randomized Study of INCB161734 Plus Standard Chemotherapy Drug Combination in Untreated KRAS G12D Metastatic Pancreatic Ductal Adenocarcinoma Patients

Colorectal cancer metastatic

INCA33890 With Standard Chemotherapy and Bevacizumab in First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

Hereditary haemochromatosis

A study to evaluate the effectiveness and safety of vamifeport in adults with hereditary hemochromatosis

Anaemia+1

A Phase 3 Study of Elritercept Versus Epoetin Alfa in ESA‑Naïve Adults with Lower‑Risk Myelodysplastic Syndrome Requiring Red Blood Cell Transfusions

Acute lymphocytic leukaemia

Study of Blinatumomab and a drug combination for older adults with newly diagnosed Philadelphia-negative B-cell precursor Acute Lymphoblastic Leukemia

Interstitial lung disease

Efficacy and Safety of Subcutaneous Belimumab in Adults with Connective Tissue Disease-Associated Interstitial Lung Disease

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