In Thionville, researchers are recruiting patients with influenza‑induced acute hypoxemic respiratory failure to compare the effect of dexamethasone with placebo on critical outcomes. Evaluation of all‑cause mortality within 28 days Measurement of ventilator‑free days Assessment of ICU‑free days as a secondary endpoint Hierarchical composite endpoint analysis The trial aims to clarify whether early corticosteroid therapy can improve survival and reduce intensive care burden in severe influenza pneumonia.

IgA Nephropathy

A parallel study focuses on patients with biopsy‑proven IgA nephropathy and significant albuminuria, testing the potential of Hydroxychloroquine to slow renal function decline. Long‑term preservation of glomerular filtration rate Reduction of albuminuria levels Interaction with optimized RAAS inhibitor therapy Influence of Oxford classification lesions on treatment response This three‑year investigation seeks to determine if the drug can become a valuable adjunct in managing progressive kidney disease.

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Clinical trials in Thionville

2 trials in Thionville

IgA nephropathy

Study on the Effect of Hydroxychloroquine for Patients with IgA Nephropathy and High Albumin Levels

Pneumonia+1

Early Use of Dexamethasone versus Sodium Chloride Placebo in Patients with Severe Influenza-Induced Acute Hypoxemic Respiratory Failure (Phase III Randomized Trial)

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