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Clinical trials in Thionville

4 clinical trials in Thionville, France. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Thionville at a glance
4
clinical trials
  • Paediatric trials0
  • Research sites0
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4 trials in Thionville

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Obesity+1

Recruiting

A Phase III Study of Lenbelintide in Adults with Obesity or Overweight and Weight‑Related Comorbidity Without Type 2 Diabetes

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:AZD6234
  • Sponsor:AstraZeneca AB

Study on the Effectiveness of Cemiplimab, Carboplatin, and Paclitaxel for Unfit or Elderly Patients with Unresectable Stage III Non-Small Cell Lung Cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Intergroupe Francophone De Cancerologie Thoracique

IgA nephropathy

Recruiting

Study on the Effect of Hydroxychloroquine for Patients with IgA Nephropathy and High Albumin Levels

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Hydroxychloroquine Sulfate
  • Sponsor:Centre Hospitalier Universitaire De Saint Etienne

Pneumonia+1

Not yet recruiting

Early Use of Dexamethasone versus Sodium Chloride Placebo in Patients with Severe Influenza-Induced Acute Hypoxemic Respiratory Failure (Phase III Randomized Trial)

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Sodium Chloride
  • Sponsor:Centre Hospital Region Metz Thionville

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Clinical research in Thionville

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01 Respiratory Tract Diseases

In Thionville, researchers are recruiting patients with influenza‑induced acute hypoxemic respiratory failure to compare the effect of dexamethasone with placebo on critical outcomes.

  • Evaluation of all‑cause mortality within 28 days
  • Measurement of ventilator‑free days
  • Assessment of ICU‑free days as a secondary endpoint
  • Hierarchical composite endpoint analysis

The trial aims to clarify whether early corticosteroid therapy can improve survival and reduce intensive care burden in severe influenza pneumonia.

02 IgA Nephropathy

A parallel study focuses on patients with biopsy‑proven IgA nephropathy and significant albuminuria, testing the potential of hydroxychloroquine to slow renal function decline.

  • Long‑term preservation of glomerular filtration rate
  • Reduction of albuminuria levels
  • Interaction with optimized RAAS inhibitor therapy
  • Influence of Oxford classification lesions on treatment response

This three‑year investigation seeks to determine if the drug can become a valuable adjunct in managing progressive kidney disease.

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