Clinical trials in Sofia – page 12

772 clinical trials in Sofia, Bulgaria across 17 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

Sofia at a glance

772

clinical trials

Research sites17

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772 trials in Sofia

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Systemic lupus erythematosus

Recruiting

Evaluation of Long-Term Safety and Efficacy of Litifilimab in Adults with Active Systemic Lupus Erythematosus: A Phase 3 Multicenter, Randomized, Dose-Blind Study

Investigational

Evaluation of Long-Term Safety and Efficacy of Litifilimab in Adults with Active Systemic Lupus Erythematosus: A Phase 3 Multicenter, Randomized, Dose-Blind Study

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Substances:Litifilimab
Sponsor:Biogen Idec Research Limited

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Cardiac failure+1

Recruiting

A study of finerenone with standard treatment for children and young adults from birth to 18 years with heart failure and left ventricular systolic dysfunction

InvestigationalNo placebo

A study of finerenone with standard treatment for children and young adults from birth to 18 years with heart failure and left ventricular systolic dysfunction

InvestigationalNo placebo

Bulgaria

Participants:0–17 years · 18–64 years
Substances:Finerenone
Sponsor:Bayer AG

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Cardiac failure+1

Recruiting

A study of finerenone added to standard treatment in children aged 6 months to under 18 years with heart failure and reduced left heart pumping function

Investigational

A study of finerenone added to standard treatment in children aged 6 months to under 18 years with heart failure and reduced left heart pumping function

Investigational

Bulgaria

Participants:0–17 years
Substances:Finerenone
Sponsor:Bayer AG

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Hepatitis D+1

Recruiting

Study of GS-4321 for Healthy People and Patients With Chronic Hepatitis Delta Virus Infection

Investigational

Study of GS-4321 for Healthy People and Patients With Chronic Hepatitis Delta Virus Infection

Investigational

Bulgaria

Participants:18–64 years · 65+ years · Healthy volunteers
Substances:GS-4321
Sponsor:Gilead Sciences Inc.

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Neovascular age-related macular degeneration

Recruiting

Study of Surabgene Lomparvovec Compared to Ranibizumab for Adults with Wet Age-Related Macular Degeneration

Registered drugNo placebo

Study of Surabgene Lomparvovec Compared to Ranibizumab for Adults with Wet Age-Related Macular Degeneration

Registered drugNo placebo

Bulgaria

Participants:18–64 years · 65+ years
Substances:Ranibizumab
Sponsor:AbbVie Deutschland GmbH & Co. KG

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Myasthenia gravis

Recruiting

Study of oral cladribine compared to placebo for patients with generalized myasthenia gravis

Registered drug

Study of oral cladribine compared to placebo for patients with generalized myasthenia gravis

Registered drug

Bulgaria

Participants:18–64 years · 65+ years
Substances:Cladribine
Sponsor:Merck Healthcare KGaA

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Major depression

Recruiting

A Study of SPT-300 Compared to Placebo for Adults with Major Depressive Disorder with or without Anxious Distress

Investigational

A Study of SPT-300 Compared to Placebo for Adults with Major Depressive Disorder with or without Anxious Distress

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Sponsor:Seaport Therapeutics Inc.

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Chronic inflammatory demyelinating polyradiculoneuropathy

Recruiting

A study to test if empasiprubart can improve function and is safe for adults with chronic inflammatory demyelinating polyneuropathy

Investigational

A study to test if empasiprubart can improve function and is safe for adults with chronic inflammatory demyelinating polyneuropathy

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Substances:Empasiprubart
Sponsor:Argenx

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Parkinson's disease

Recruiting

A Study Testing the Safety of IRL757 in Adults with Parkinson's Disease Who Have Apathy

Investigational

A Study Testing the Safety of IRL757 in Adults with Parkinson's Disease Who Have Apathy

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Sponsor:Integrative Research Laboratories Sweden AB

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Respiratory syncytial virus infection

Recruiting

A Study of S-337395 for Adults Not in Hospital with Respiratory Syncytial Virus Who Are at High Risk of Severe Disease

Investigational

A Study of S-337395 for Adults Not in Hospital with Respiratory Syncytial Virus Who Are at High Risk of Severe Disease

Investigational

Bulgaria

Participants:18–64 years · 65+ years
Sponsor:Shionogi B.V.

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Non-small cell lung cancer

Recruiting

A Study Comparing PF-08046054 to Docetaxel in Adults with Previously Treated PD-L1 Positive Non-Small Cell Lung Cancer

Registered drugNo placebo

A Study Comparing PF-08046054 to Docetaxel in Adults with Previously Treated PD-L1 Positive Non-Small Cell Lung Cancer

Registered drugNo placebo

Bulgaria

Participants:18–64 years · 65+ years
Substances:Docetaxel
Sponsor:Pfizer Inc.

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Chronic obstructive pulmonary disease

Recruiting

A Study of Depemokimab Compared to Placebo in Adults with Chronic Obstructive Pulmonary Disease and Type 2 Inflammation

Registered drug

A Study of Depemokimab Compared to Placebo in Adults with Chronic Obstructive Pulmonary Disease and Type 2 Inflammation

Registered drug

Bulgaria

Participants:18–64 years · 65+ years
Substances:Depemokimab
Sponsor:Glaxosmithkline Research & Development Limited

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Clinical research in Sofia

What the registry says about research in the country

01 Respiratory Research

Clinical studies focusing on respiratory infections and conditions, including trials for RSV, human metapneumovirus, and influenza vaccines in older adults. Research also includes investigations into asthma treatments and chronic rhinosinusitis management.

Respiratory Syncytial Virus (RSV)
Influenza Prevention
Chronic Rhinosinusitis
Asthma Management

02 Dermatological Studies

Comprehensive research into various skin conditions, evaluating new treatments for chronic urticaria, hidradenitis suppurativa, and different forms of psoriasis. These trials aim to improve patient outcomes through innovative therapeutic approaches.

Chronic Spontaneous Urticaria
Hidradenitis Suppurativa
Genital Psoriasis
Plaque Psoriasis

03 Autoimmune Disorders

Groundbreaking studies examining treatments for various autoimmune conditions, including multiple sclerosis, Sjögren's disease, and systemic sclerosis. Research focuses on developing targeted therapies to manage these chronic conditions.

Multiple Sclerosis
Sjögren's Disease
Systemic Sclerosis
Psoriatic Arthritis

04 Metabolic and Cardiovascular Research

Studies investigating treatments for metabolic disorders and heart conditions, including research on hypertriglyceridemia, obesity management, and heart failure prevention. Focus on both therapeutic interventions and preventive measures.

Hypertriglyceridemia
Obesity Management
Heart Failure Prevention
Cardiovascular Health

05 Oncology Research

Advanced clinical trials focusing on breast cancer treatments and blood disorders, particularly investigating new therapeutic approaches for advanced/metastatic breast cancer and myelodysplastic syndrome.

Advanced Breast Cancer
Myelodysplastic Syndrome
Targeted Therapies

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Clinical trials in Sofia – page 12

772 trials in Sofia

Systemic lupus erythematosus

Evaluation of Long-Term Safety and Efficacy of Litifilimab in Adults with Active Systemic Lupus Erythematosus: A Phase 3 Multicenter, Randomized, Dose-Blind Study

Cardiac failure+1

A study of finerenone with standard treatment for children and young adults from birth to 18 years with heart failure and left ventricular systolic dysfunction

Cardiac failure+1

A study of finerenone added to standard treatment in children aged 6 months to under 18 years with heart failure and reduced left heart pumping function

Hepatitis D+1

Study of GS-4321 for Healthy People and Patients With Chronic Hepatitis Delta Virus Infection

Neovascular age-related macular degeneration

Study of Surabgene Lomparvovec Compared to Ranibizumab for Adults with Wet Age-Related Macular Degeneration

Myasthenia gravis

Study of oral cladribine compared to placebo for patients with generalized myasthenia gravis

Major depression

A Study of SPT-300 Compared to Placebo for Adults with Major Depressive Disorder with or without Anxious Distress

Chronic inflammatory demyelinating polyradiculoneuropathy

A study to test if empasiprubart can improve function and is safe for adults with chronic inflammatory demyelinating polyneuropathy

Parkinson's disease

A Study Testing the Safety of IRL757 in Adults with Parkinson's Disease Who Have Apathy

Respiratory syncytial virus infection

A Study of S-337395 for Adults Not in Hospital with Respiratory Syncytial Virus Who Are at High Risk of Severe Disease

Non-small cell lung cancer

A Study Comparing PF-08046054 to Docetaxel in Adults with Previously Treated PD-L1 Positive Non-Small Cell Lung Cancer

Chronic obstructive pulmonary disease

A Study of Depemokimab Compared to Placebo in Adults with Chronic Obstructive Pulmonary Disease and Type 2 Inflammation

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