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Clinical trials in Sliven

117 clinical trials in Sliven, Bulgaria across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

Sliven at a glance
117
clinical trials
  • Research sites1
Type of trial
Recruitment status
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117 trials in Sliven

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Cardiac failure

Recruiting

Study of maridebart cafraglutide for patients with heart failure with preserved or mildly reduced ejection fraction and obesity

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Maridebart Cafraglutide
  • Sponsor:Amgen Inc.

Phase III Randomized Study of Balcinrenone and Dapagliflozin Versus Dapagliflozin on Renal and Cardiovascular Outcomes in Patients with Chronic Kidney Disease Stage 3b‑4

Registered drug
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Balcinrenone
  • Sponsor:AstraZeneca AB

Obesity+1

Recruiting

A Phase III Study of Lenbelintide in Adults with Obesity or Overweight and Weight‑Related Comorbidity Without Type 2 Diabetes

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:AZD6234
  • Sponsor:AstraZeneca AB

Obesity+2

Recruiting

Effect of zenagamtide on major adverse cardiovascular events in overweight or obese adults with established atherosclerotic cardiovascular disease

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years
  • Substances:Zenagamtide
  • Sponsor:Novo Nordisk A/S

Graves' disease

Recruiting

Phase 3 Randomized Placebo‑Controlled Study of Efgartigimod Alfa in Adults with Graves’ Disease Inadequately Controlled by Antithyroid Drugs

Registered drug
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Efgartigimod Alfa
  • Sponsor:Argenx

A Phase III Randomized Double‑Blind Study of Elecoglipron for Adults with Type 2 Diabetes on Insulin

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:AZD5004
  • Sponsor:AstraZeneca AB

Randomized Phase III trial of elecoglipron plus dapagliflozin on kidney outcomes and mortality in adults with chronic kidney disease

Registered drug
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:AZD5004
  • Sponsor:AstraZeneca AB

A Phase III Study of Elecoglipron Compared with Semaglutide for Adults with Type 2 Diabetes Mellitus

Registered drugNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:AZD5004
  • Sponsor:AstraZeneca AB

A Phase 3 Study of Efimosfermin Alfa to Assess Safety and Tolerability in Adults with F2‑F3 Stage Metabolic Dysfunction‑Associated Steatohepatitis (MASH)

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Efimosfermin alfa
  • Sponsor:Glaxosmithkline Research & Development Limited

A study to evaluate the long-term safety and effectiveness of barzolvolimab in patients with chronic spontaneous urticaria

Registered drugNo placebo
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Epinephrine
  • Sponsor:Celldex Therapeutics Inc.

Study of Zilebesiran Added to Standard Treatment to Reduce Heart Problems in Adults with High Blood Pressure and Heart Disease Risk

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Zilebesiran
  • Sponsor:Alnylam Pharmaceuticals Inc.

Study of AZD6793 tablets to reduce flare-ups in adults with moderate to very severe chronic obstructive pulmonary disease (COPD)

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:AZD6793
  • Sponsor:AstraZeneca AB

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Clinical research in Sliven

What the registry says about research in the country

01 Respiratory Medicine

Clinical trials focusing on respiratory conditions including innovative treatments for asthma management and COPD. Research includes evaluation of new inhalation therapies and combination treatments.

  • Moderate to Severe Asthma
  • Chronic Obstructive Pulmonary Disease
  • Inhaler Technology Development

Studies aim to improve symptom control and quality of life for patients with chronic respiratory conditions.

02 Cardiovascular Research

Extensive research into cardiovascular diseases and related conditions, including studies on heart failure, atherosclerosis, and hypertension management.

  • Atherosclerotic Cardiovascular Disease
  • Heart Failure Management
  • Hypertriglyceridemia Treatment

Focus on preventing major cardiovascular events and improving patient outcomes through innovative therapies.

03 Immunology and Inflammation

Studies examining new treatments for autoimmune disorders and inflammatory conditions, including breakthrough therapies for various forms of arthritis.

  • Psoriatic Arthritis
  • Sjögren's Disease
  • Ulcerative Colitis

Research aims to reduce inflammation and improve disease management in chronic conditions.

04 Infectious Diseases

Research focusing on viral infections and their treatment, including studies of influenza vaccines and therapeutic approaches.

  • Influenza Prevention
  • Hepatitis Delta Treatment
  • Urinary Tract Infections

Emphasis on developing effective treatments and preventive measures for various infectious conditions.

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