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Clinical trials in Siegen

25 clinical trials in Siegen, Germany. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Siegen at a glance
25
clinical trials
  • Not yet recruiting0
  • Paediatric trials0
  • Research sites0
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25 trials in Siegen

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Cardiac failure

Recruiting

Study of maridebart cafraglutide for patients with heart failure with preserved or mildly reduced ejection fraction and obesity

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Maridebart Cafraglutide
  • Sponsor:Amgen Inc.

Plasma cell myeloma

Recruiting

Accelerating improvement with teclistamab plus standard drug combination in newly diagnosed transplant‑eligible multiple myeloma patients

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Bortezomib
  • Sponsor:Universitaetsklinikum Heidelberg AöR

Hodgkin's disease

Recruiting

A Study of Pembrolizumab and Radiotherapy for Patients with Early-Stage Favorable Classic Hodgkin Lymphoma

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Pembrolizumab
  • Sponsor:University Of Cologne

Hormone receptor positive breast cancer+1

Recruiting

Study of patritumab deruxtecan versus drug combination in patients with hormone receptor-positive, HER2-negative advanced or metastatic breast cancer

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Capecitabine
  • Sponsor:Merck Sharp & Dohme LLC

Mantle cell lymphoma

Recruiting

Study on the Effectiveness and Safety of Sonrotoclax and Zanubrutinib for Adults with Relapsed or Refractory Mantle Cell Lymphoma

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Zanubrutinib
  • Sponsor:BeOne Medicines AG

Colon cancer stage III+1

Recruiting

Study on Pre-Operative Chemotherapy with Disodium Folinate, Oxaliplatin, and Fluorouracil for Patients with Advanced Resectable Colon Cancer

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Calcium Folinate
  • Sponsor:Charite Universitaetsmedizin Berlin KöR

Diffuse large B-cell lymphoma

Recruiting

Study on High-Dose Chemotherapy with Cytarabine and Drug Combination for Elderly Patients with Primary CNS Lymphoma

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:65+ years
  • Substances:Busulfan
  • Sponsor:Medical Center - University Of Freiburg

Colorectal cancer metastatic

Recruiting

Study on Chemotherapy with Irinotecan, Fluorouracil, and Oxaliplatin for Patients with Metastatic Colorectal Cancer After Surgery or Ablation

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Capecitabine
  • Sponsor:Charite Universitaetsmedizin Berlin KöR

Double hit lymphoma+7

Recruiting

Study on Acalabrutinib with Rituximab and Drug Combination for Older Adults with Untreated Diffuse Large B-Cell Lymphoma

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:Acalabrutinib
  • Sponsor:Universitaet Des Saarlandes

Neuralgia+1

Not recruiting

Study on LY3848575 for Reducing Pain in Patients with Distal Sensory Polyneuropathy

Investigational
Countries:GermanyGermany
  • Participants:18–64 years · 65+ years
  • Substances:LY3848575
  • Sponsor:Eli Lilly & Co.

Migraine

Not recruiting

Study on Atogepant for Preventing Menstrual Migraine in Women

Investigational
Countries:GermanyGermany
  • Participants:18–64 years
  • Substances:Atogepant
  • Sponsor:AbbVie Deutschland GmbH & Co. KG

Multiple sclerosis relapse

Not recruiting

Study on Long-Term Safety and Effectiveness of Ofatumumab for Patients with Relapsing Multiple Sclerosis

Registered drugNo placebo
Countries:GermanyGermany
  • Participants:18–64 years
  • Substances:Ofatumumab
  • Sponsor:Novartis Pharma AG

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Clinical research in Siegen

What the registry says about research in the country

01 Neurological Disorders

Innovative research focusing on multiple sclerosis treatments, including comparative studies of medications like ofatumumab and ocrelizumab. Clinical trials are evaluating new therapeutic approaches for both episodic and chronic migraine management.

  • Relapsing Multiple Sclerosis (RMS)
  • Menstrual Migraine
  • Treatment Effectiveness Studies

Studies emphasize long-term safety and effectiveness of treatments for neurological conditions.

02 Oncology Research

Comprehensive studies in colorectal cancer treatment, including pre-operative and post-resection therapies. Advanced research in breast cancer and lymphoma treatments with innovative therapeutic approaches.

  • Colon Cancer Management
  • Hodgkin Lymphoma
  • Breast Cancer Therapy

Trials focus on personalized treatment approaches and improved patient outcomes.

03 Mental Health & Cardiac Care

Clinical research addressing Major Depressive Disorder and schizophrenia, alongside studies in cardiac conditions. Investigations include new treatment options for heart failure patients.

  • Depression Treatment Studies
  • Schizophrenia Management
  • Cardiac Function Research

Focus on improving patient outcomes through innovative therapeutic approaches.

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