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Clinical trials in Ruse – page 14

184 clinical trials in Ruse, Bulgaria. Every trial is listed in the EU Clinical Trials Register and updated daily.

Ruse at a glance
184
clinical trials
  • Research sites0
Type of trial
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184 trials in Ruse

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Cachexia

Not recruiting

Study of ponsegromab for patients with cancer cachexia and elevated GDF-15 levels

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Ponsegromab
  • Sponsor:Pfizer Inc.

Study on Long-Term Safety of Itepekimab for Patients with Chronic Obstructive Pulmonary Disease (COPD)

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Itepekimab
  • Sponsor:Sanofi-Aventis Recherche & Developpement

Asthmatic crisis

Not recruiting

Study on the Effects of Verekitug (UPB-101) for Adults with Severe Asthma

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Human IgG1 kappa monoclonal antibody against CRLF2
  • Sponsor:Upstream Bio Inc.

Study on the Safety and Effectiveness of Tovinontrine for Adults with Chronic Heart Failure with Reduced Ejection Fraction

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Tovinontrine
  • Sponsor:Cardurion Pharmaceuticals Inc.

COVID-19

Not recruiting

Study on the Safety and Effectiveness of Nirmatrelvir and Ritonavir for Nonhospitalized Children with COVID-19 at Risk of Severe Illness

InvestigationalNo placebo
Countries:BulgariaBulgaria
  • Participants:0–17 years
  • Substances:Nirmatrelvir
  • Sponsor:Pfizer Inc.

Study on the Safety and Effectiveness of Tovinontrine for Adults with Chronic Heart Failure with Preserved Ejection Fraction

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Tovinontrine
  • Sponsor:Cardurion Pharmaceuticals Inc.

Major depression

Not recruiting

Testing BI 1569912 for Major Depressive Disorder in Patients Using Antidepressants

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Sponsor:Boehringer Ingelheim International GmbH

Study on the Effectiveness and Safety of EDP-938 for Adults with High-Risk Respiratory Syncytial Virus (RSV) Infection

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Zelicapavir
  • Sponsor:Enanta Pharmaceuticals Inc.

Hypercholesterolaemia

Not recruiting

Study on Inclisiran and Rosuvastatin for Lowering Cholesterol in Patients with High Cholesterol Levels

Registered drug
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Inclisiran
  • Sponsor:Novartis Pharma AG

Asthma

Not recruiting

Study on the Long-term Effects of Dupilumab in Preventing Lung Function Decline in Adults with Uncontrolled Moderate to Severe Asthma

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Dupilumab
  • Sponsor:Sanofi-Aventis Recherche & Developpement

Atrial fibrillation+2

Not recruiting

Study on Asundexian and Apixaban for Preventing Stroke in Adults with Atrial Fibrillation at Risk for Stroke

Registered drug
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Apixaban
  • Sponsor:Bayer AG

Study on the Effectiveness and Safety of PLS240 for Treating Secondary Hyperparathyroidism in Patients with End Stage Kidney Disease on Hemodialysis

Investigational
Countries:BulgariaBulgaria
  • Participants:18–64 years · 65+ years
  • Substances:Upacicalcet Sodium Hydrate
  • Sponsor:Pathalys Pharma Inc.

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Clinical research in Ruse

What the registry says about research in the country

01 Respiratory Diseases

Current clinical research focuses on asthma management and innovative treatments for respiratory conditions, including trials of new inhaler formulations and targeted therapies for uncontrolled asthma patients.

  • Asthma treatment optimization
  • Severe viral lung infections
  • Influenza prevention

Studies are evaluating both novel compounds and improved delivery systems for existing medications.

02 Cardiovascular Health

Breakthrough research in cardiovascular disease prevention and treatment, with particular attention to heart failure prevention and innovative approaches to managing cardiac conditions.

  • Heart failure prevention
  • Hypertrophic cardiomyopathy
  • Major cardiovascular events reduction

Multiple trials are exploring combination therapies and new molecular entities for cardiac conditions.

03 Immunology and Inflammation

Extensive research into psoriatic arthritis treatments, including both biologic-naive and biologic-experienced patient populations.

  • Psoriatic arthritis therapies
  • Prurigo nodularis treatment
  • Inflammatory conditions

Studies are evaluating novel therapeutic approaches for various inflammatory conditions.

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