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Clinical trials in Rillieux-la-Pape

2 clinical trials in Rillieux-la-Pape, France. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Rillieux-la-Pape at a glance
2
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  • Paediatric trials0
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2 trials in Rillieux-la-Pape

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Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Capecitabine
  • Sponsor:Unicancer
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:FRUQUINTINIB
  • Sponsor:Fondation Franc.Cancerologie Digestive

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Clinical research in Rillieux-la-Pape

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01 Rillieux-la-Pape
Metastatic Oeso‑Gastric Adenocarcinoma
A randomized trial in Rillieux‑la‑Pape is comparing a novel oral combo therapy with standard treatment to improve outcomes for patients with advanced gastric and esophageal tumors. Assessment of overall survival between the combination and monotherapy arms. Evaluation of trifluridine/tipiracil + fruquintinib as a targeted regimen. Investigation of safety and quality‑of‑life benefits. Collaboration between two local research sites. Results aim to define a new standard for metastatic oeso‑gastric adenocarcinoma and could expand therapeutic options in Europe.
Stage III Colorectal Cancer – ctDNA Guided Chemotherapy
In Rillieux‑la‑Pape, researchers are testing blood‑based stratification to personalize adjuvant chemotherapy after surgical removal of stage III colon tumors. Use of ctDNA status to assign patients to de‑escalation or escalation arms. Non‑inferiority trial of 6‑month capecitabine alone versus 3‑month capecitabine + oxaliplatin. Superiority trial of 6‑month FOLFIRINOX versus 6‑month FOLFOX in ctDNA‑positive patients. Primary focus on 3‑year disease‑free survival as the efficacy endpoint. Findings could reshape standard adjuvant therapy by matching intensity to residual molecular risk.
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