Innovative research focusing on membranoproliferative glomerulonephritis and related conditions, evaluating novel therapeutic approaches including iptacopan and pegcetacoplan for treating various forms of kidney inflammation.

IC-MPGN Treatment Evaluation
C3 Glomerulopathy Research
Post-Transplant Recurrence Studies

Multiple trials aim to reduce proteinuria and improve long-term kidney function outcomes.

02 Nephropathy Research

Comprehensive studies examining treatments for IgA Nephropathy and membranous nephropathy, including investigations of sparsentan and specialized antibody therapies for patients resistant to conventional treatments.

Primary Membranous Nephropathy
IgA Nephropathy Interventions
Antibody-Based Treatments

Focus on proteinuria reduction and preservation of renal function in various nephropathy types.

03 Chronic Kidney Disease

Advanced research into non-diabetic chronic kidney disease, exploring new therapeutic options including finerenone and investigating treatments for complications like hyperkalemia.

Disease Progression Prevention
Hyperkalemia Management
Long-term Kidney Function

Studies aim to delay disease progression and improve standard of care outcomes.

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Clinical trials in Ranica – page 129

2 668 trials in Ranica

Arteriosclerosis

Long-term safety study of pelacarsen in patients with atherosclerotic cardiovascular disease who completed the Lp(a)HORIZON trial

Cystic fibrosis respiratory infection suppression

Study of inhaled BX004 bacteriophage treatment for adults with cystic fibrosis who have chronic Pseudomonas aeruginosa lung infection

Adenocarcinoma gastric+3

Study of zolbetuximab, pembrolizumab and chemotherapy in adults with HER2-negative, Claudin 18.

Meningococcal infection

Study of rMenB+OMV NZ meningococcal group B vaccine immune response and safety in previously vaccinated healthy participants aged 10 to 20 years

Ovarian cancer

Study of Saruparib in Patients with Advanced or Recurrent Ovarian Cancer to Assess Safety and Effectiveness

Neoplasm malignant

Study of S095035 and TNG462 in adults with advanced or metastatic solid tumors with MTAP deletion

Acromegaly

Study of ALXN2420 with somatostatin analogs for adults with acromegaly to evaluate effectiveness in lowering IGF-1 levels

Hypersomnia

Study of ALKS 2680 to treat excessive daytime sleepiness in people with idiopathic hypersomnia

Primary hyperaldosteronism

Study of baxdrostat compared to placebo to treat adults with primary aldosteronism

Idiopathic pulmonary fibrosis

Study of BI 765423 given by intravenous infusion for patients with idiopathic pulmonary fibrosis with or without standard treatment

Chronic kidney disease

Study of vicadrostat and empagliflozin given together or separately in people with chronic kidney disease to test safety and effectiveness

Hidradenitis

Study of ruxolitinib cream for treating hidradenitis suppurativa in adult patients

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Clinical research in Ranica

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