Innovative research focusing on membranoproliferative glomerulonephritis and related conditions, evaluating novel therapeutic approaches including iptacopan and pegcetacoplan for treating various forms of kidney inflammation.

IC-MPGN Treatment Evaluation
C3 Glomerulopathy Research
Post-Transplant Recurrence Studies

Multiple trials aim to reduce proteinuria and improve long-term kidney function outcomes.

02 Nephropathy Research

Comprehensive studies examining treatments for IgA Nephropathy and membranous nephropathy, including investigations of sparsentan and specialized antibody therapies for patients resistant to conventional treatments.

Primary Membranous Nephropathy
IgA Nephropathy Interventions
Antibody-Based Treatments

Focus on proteinuria reduction and preservation of renal function in various nephropathy types.

03 Chronic Kidney Disease

Advanced research into non-diabetic chronic kidney disease, exploring new therapeutic options including finerenone and investigating treatments for complications like hyperkalemia.

Disease Progression Prevention
Hyperkalemia Management
Long-term Kidney Function

Studies aim to delay disease progression and improve standard of care outcomes.

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Clinical trials in Ranica – page 104

2 668 trials in Ranica

Ductal adenocarcinoma of pancreas

Study Comparing Short-Course and Long-Course Chemotherapy with mFOLFIRINOX or PAXG for Patients with Stage I-III Pancreatic Cancer

Chronic lymphocytic leukaemia

Study on Lymph Node Changes in Chronic Lymphocytic Leukemia Patients Treated with Venetoclax

Hypertrophic cardiomyopathy

Study on Mavacamten for Adults with Symptomatic Obstructive Hypertrophic Cardiomyopathy

Anaemia of chronic disease

Study on Efepoetin Alfa and Darbepoetin Alfa for Treating Anemia in Patients with Chronic Kidney Disease on Dialysis

Muscular dystrophy

Study on the Safety of ATA-200 Gene Therapy for Patients with Limb-Girdle Muscular Dystrophy Type R5

Endometrial cancer

Study Comparing Chemotherapy Alone to Dostarlimab, Paclitaxel, and Carboplatin for Patients with Advanced or Metastatic Endometrial Cancer

Hypophosphatasia

Study of ALXN1850 for Children Aged 2 to 12 with Hypophosphatasia Who Have Not Previously Received Asfotase Alfa Treatment

Restless legs syndrome

Study on the Effects of Dextromethadone Hydrochloride for Patients with Moderate to Very Severe Restless Legs Syndrome

Colorectal cancer+4

Study of INCB099280 and Adagrasib for Adults with Advanced Solid Tumors with KRASG12C Mutation

End stage renal disease

Study on the Safety of Glucothera Plus for Children with End-Stage Kidney Disease Undergoing Peritoneal Dialysis

Hormone receptor positive HER2 negative breast cancer

Study on the Effectiveness of Abemaciclib, Inavolisib, and Giredestrant in Patients with Early HR-positive/HER2-negative Breast Cancer

Congenital absence of bile ducts

Study on Obeticholic Acid for Children with Biliary Atresia After Kasai Procedure

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Clinical research in Ranica

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