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Clinical trials in Pardubice – page 18

574 clinical trials in Pardubice, Czechia. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Pardubice at a glance
574
clinical trials
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574 trials in Pardubice

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Rheumatoid arthritis

Not yet recruiting

Study on the Effectiveness and Safety of Tocilizumab and Methotrexate for Adults with Moderate to Severe Rheumatoid Arthritis

Registered drugNo placebo
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Tocilizumab
  • Sponsor:Dr Reddy's Laboratories Limited

Randomized phase III study of AAA817 plus an androgen receptor pathway inhibitor in adult men with PSMA‑positive metastatic castration‑resistant prostate cancer

Registered drugNo placebo
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Abiraterone
  • Sponsor:Novartis Pharma AG

Multiple sclerosis

Not yet recruiting

Long‑Term Safety and Tolerability of Frexalimab Drug Combination in Adults with Multiple Sclerosis

Registered drug
Countries:CzechiaCzechia
  • Participants:18–64 years
  • Substances:Colestyramine
  • Sponsor:Sanofi-Aventis Recherche & Developpement

Breast cancer+2

Not yet recruiting

Gedatolisib with drug combination versus standard therapy as first‑line treatment for patients with advanced HR‑positive HER2‑negative breast cancer

Registered drugNo placebo
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Dexamethasone
  • Sponsor:Celcuity Inc.

Dermatitis atopic

Not yet recruiting

Study of the safety and effectiveness of TRIV-573 injections in adults with moderate to severe atopic dermatitis

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Sponsor:Triveni Bio Inc.

Anaemia+1

Not yet recruiting

Study of Elritercept (TAK‑226) with Ruxolitinib vs Placebo in Patients with Myelofibrosis and Anemia on Ruxolitinib Therapy

Registered drug
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Ruxolitinib
  • Sponsor:Takeda Development Center Americas Inc.

Infection prophylaxis

Not yet recruiting

Study of human normal immunoglobulin to prevent major infections in patients with hypogammaglobulinemia and autoimmune/rheumatic disease on B‑cell depletion therapy

Registered drug
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Sodium Chloride
  • Sponsor:Octapharma Pharmazeutika Produktionsgesellschaft mbH

Secondary immunodeficiency

Not yet recruiting

Study of Human Normal Immunoglobulin in Adults with Secondary Immune Deficiency after CAR T‑cell or T‑cell Redirecting Therapy for Hematologic Malignancies

Registered drugNo placebo
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Human Normal Immunoglobulin
  • Sponsor:CSL Behring LLC

Study of oral STL303 hydrochloride to assess safety and effectiveness in adults with geographic atrophy secondary to age‑related macular degeneration

Investigational
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Sponsor:Sitala Bio Limited

Safety and Efficacy of Two Doses of OCUL101 Compared with Aflibercept in Patients with Neovascular Age‑Related Macular Degeneration

Registered drugNo placebo
Countries:CzechiaCzechia
  • Participants:65+ years
  • Substances:Aflibercept
  • Sponsor:Shenzhen Oculgen Biomedical Technology Co. Ltd.

Safety and Immune Response of GBS‑NN/NN2 Vaccine in Pregnant Women and Their Infants to Prevent Group B Streptococcus Infection

Investigational
Countries:CzechiaCzechia
  • Participants:0–17 years · 18–64 years · Healthy volunteers
  • Substances:GBS-NN
  • Sponsor:Minervax ApS

Anxiety

Not yet recruiting

Efficacy of Etifoxine in Adults with Adjustment Disorder with Anxiety: A Randomized, Double‑Blind, Placebo‑Controlled Trial

Registered drug
Countries:CzechiaCzechia
  • Participants:18–64 years · 65+ years
  • Substances:Etifoxine Hydrochloride
  • Sponsor:Biocodex

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Clinical research in Pardubice

What the registry says about research in the country

01 Infectious Disease Prevention

Clinical trials focusing on vaccine development for preventable diseases, including studies of new chickenpox vaccines and advanced meningococcal vaccines for infants and children.

  • Varicella immunization
  • Meningococcal disease prevention
  • Pediatric vaccine safety

Research emphasizes immune response monitoring and safety assessment in young populations.

02 Autoimmune Conditions

Innovative research targeting various autoimmune disorders, with studies evaluating new treatments for psoriatic arthritis and multiple sclerosis.

  • Plaque psoriasis treatments
  • MS therapy advancement
  • Immune system modulation

Trials focus on developing targeted therapies for chronic inflammatory conditions.

03 Neurological Disorders

Studies investigating new therapeutic approaches for Parkinson's Disease and other neurological conditions, with emphasis on improving patient outcomes.

  • Movement disorders
  • Neurodegenerative diseases
  • Symptom management

Research aims to enhance treatment options and quality of life for patients.

04 Oncology Research

Advanced clinical trials focusing on prostate cancer treatment, particularly addressing metastatic castration-resistant cases.

  • Targeted cancer therapies
  • Hormone-resistant cancers
  • Combination treatments

Studies emphasize novel therapeutic approaches for advanced-stage cancers.

05 Musculoskeletal Conditions

Research investigating treatments for osteoarthritis and joint disorders, including innovative therapies for knee-specific conditions.

  • Pain management
  • Joint function improvement
  • Inflammatory conditions

Focus on developing both systemic and topical treatments for joint diseases.

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