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Clinical trials in Orléans

154 clinical trials in Orléans, France across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Orléans at a glance
154
clinical trials
  • Research sites1
Type of trial
Recruitment status
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154 trials in Orléans

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Chronic kidney disease

Recruiting

Phase III Randomized Study of Balcinrenone and Dapagliflozin Versus Dapagliflozin on Renal and Cardiovascular Outcomes in Patients with Chronic Kidney Disease Stage 3b‑4

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Balcinrenone
  • Sponsor:AstraZeneca AB

Chronic kidney disease

Recruiting

Randomized Phase III trial of elecoglipron plus dapagliflozin on kidney outcomes and mortality in adults with chronic kidney disease

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:AZD5004
  • Sponsor:AstraZeneca AB

Acute respiratory failure

Recruiting

Study on Tozorakimab for Patients Hospitalized with Severe Viral Lung Infections Needing Oxygen

Investigational
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Tozorakimab
  • Sponsor:AstraZeneca AB

Non-small cell lung cancer

Recruiting

A study of MK-1084 and pembrolizumab for patients with resected KRAS G12C-mutant non-small cell lung cancer

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Merck Sharp & Dohme LLC

Non-small cell lung cancer

Recruiting

Comparing sotorasib and pembrolizumab with chemotherapy for patients with advanced non-small cell lung cancer and a KRAS G12C mutation

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Calcium Folinate
  • Sponsor:Amgen Inc.

Endometrial cancer+2

Recruiting

A study comparing Rinatabart Sesutecan to other treatments in patients with endometrial cancer who have previously received platinum-based chemotherapy and PD-L1 therapy

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Paclitaxel
  • Sponsor:Genmab A/S

Haemophagocytic lymphohistiocytosis

Recruiting

Comparing the timing of etoposide and dexamethasone treatment for patients with severe sporadic hemophagocytic lymphohistiocytosis in intensive care.

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Etoposide
  • Sponsor:Assistance Publique Hopitaux De Paris

Sepsis

Recruiting

Testing a Drug Combination for Personalized Sepsis Treatment in Children and Adults with Severe Blood Infection

Registered drugNo placebo
Countries:FranceFrance
  • Participants:0–17 years · 18–64 years · 65+ years
  • Substances:Anakinra
  • Sponsor:Assistance Publique Hopitaux De Paris

Hormone receptor positive HER2 negative breast cancer

Recruiting

Study of ribociclib with or without chemotherapy for patients with hormone receptor positive, HER2 negative early breast cancer at intermediate risk

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Anastrozole
  • Sponsor:Unicancer

Sickle cell disease

Recruiting

Study of lidocaine to reduce opioid use in patients with sickle cell disease experiencing severe pain crisis

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Sodium Chloride
  • Sponsor:Centre Hospitalier Universitaire De Nantes

Bronchiolitis+1

Recruiting

Study of nirsevimab and RSV vaccine (Abrysvo) for prevention of respiratory syncytial virus infection in infants during their first year of life

Registered drugNo placebo
Countries:FranceFrance
  • Participants:0–17 years · 18–64 years
  • Substances:Nirsevimab
  • Sponsor:Centre Hospitalier Annecy Genevois

Acute respiratory failure

Recruiting

Study of High-Flow Nasal Oxygen During Intubation in Intensive Care Patients with Low Blood Oxygen Levels

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Oxygen
  • Sponsor:Centre Hospitalier Regional Universitaire De Tours

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Clinical research in Orléans

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01 Rheumatology Research

Innovative studies focusing on autoimmune conditions including trials evaluating new treatments for psoriatic and rheumatoid arthritis. Research includes assessment of maintenance therapies and novel drug combinations.

  • Psoriatic Arthritis Treatment
  • Rheumatoid Arthritis Management
  • Sjögren's Disease Therapies

Particular emphasis on evaluating long-term treatment efficacy and bone erosion prevention.

02 Oncology Studies

Comprehensive research in hematologic malignancies and solid tumors, with significant focus on multiple myeloma and breast cancer treatment innovations.

  • Multiple Myeloma Therapies
  • Triple Negative Breast Cancer
  • Pancreatic Adenocarcinoma

Advanced treatment protocols combining immunotherapy with traditional approaches.

03 Infectious Disease Research

Cutting-edge studies in HIV treatment and viral infections, exploring new therapeutic approaches and treatment optimization strategies.

  • HIV-1 Treatment Innovations
  • Viral Lung Infections
  • Immunotherapy Applications

Focus on developing long-acting treatments and improving patient outcomes.

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