Studies focusing on respiratory infections and their treatments, including innovative approaches for pneumonia and COVID-19. Trials evaluating new therapeutic options for managing severe infections and improving patient outcomes.

Community-acquired pneumonia treatments
COVID-19 therapeutic interventions
Bacterial infection management

Research includes evaluation of novel drugs and existing medications in new applications.

02 Critical Care Medicine

Investigations into intensive care treatments, focusing on conditions like septic shock and respiratory distress. Studies examining various interventions for critically ill patients.

Sepsis management protocols
Mechanical ventilation strategies
ICU-related complications

Emphasis on improving survival rates and reducing complications in critical care settings.

03 Immunology and Inflammation

Clinical trials investigating autoimmune conditions and inflammatory diseases, including studies on vasculitis and novel immunotherapy approaches.

Immunosuppression management
Autoimmune disease treatments
Inflammatory condition therapies

Research focused on developing targeted treatments for immune-mediated diseases.

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Clinical trials in Melun – page 3

35 trials in Melun

Pneumonia+1

A study testing trimodulin in hospitalized adult patients with community-acquired pneumonia including COVID-19 pneumonia

Hepatitis B

Study on Bepirovirsen for Patients with HIV and Chronic Hepatitis B on Antiretroviral Treatment

Septic shock

Study on Ivabradine for Heart Rate Control and Survival in Adults with Septic Shock

Delirium

Study on the Effects of Isoflurane and Propofol on Delirium in Intensive Care Patients on Mechanical Ventilation

Sepsis

Study of hydrocortisone and fludrocortisone combination versus placebo in adults with sepsis in intensive care unit to determine corticosteroid response

Critical illness

Study on Hydrocortisone and Fludrocortisone for Adults with Critical Illness-Related Corticosteroid Insufficiency

Giant cell arteritis

Study on Tocilizumab and Steroids for Patients with Giant Cell Arteritis and Cerebrovascular Involvement

HIV infection

Study Comparing Integrase Inhibitor (Bictegravir) and Boosted Protease Inhibitor (Darunavir) Treatments for Patients with Advanced HIV Infection

Cardiac arrest

Study on the Effectiveness of High-Dose Vitamin C for Patients with Shock After Cardiac Arrest

Pneumonia

Study on the Effectiveness of Co-Trimoxazole for Treating Ventilator-Associated Pneumonia in ICU Patients Compared to a Drug Combination

Study of oseltamivir and paracetamol blood levels in critically ill patients with severe influenza requiring mechanical ventilation

Study of oseltamivir and paracetamol blood levels in critically ill patients with severe influenza requiring mechanical ventilation

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