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Clinical trials in Mechelen – page 25

1 898 clinical trials in Mechelen, Belgium across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

Mechelen at a glance
1 898
clinical trials
  • Research sites1
Type of trial
Recruitment status
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1 898 trials in Mechelen

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Cardiac failure

Recruiting

A study testing the reduction of heart failure drug combination in patients with heart failure in remission

Registered drugNo placebo
Countries:BelgiumBelgium
  • Participants:18–64 years · 65+ years
  • Substances:Bisoprolol Fumarate
  • Sponsor:Ziekenhuis Oost Limburg

Respiratory syncytial virus infection

Recruiting

Study of RSV vaccine and nirsevimab combination to prevent RSV infection in infants up to 12 months of age

Registered drugNo placebo
Countries:BelgiumBelgium
  • Participants:0–17 years · 18–64 years · Healthy volunteers
  • Substances:Nirsevimab
  • Sponsor:Fondazione Penta Ets

Hereditary angioedema

Recruiting

A Study of ADX-324 to Prevent Attacks in Patients With Hereditary Angioedema

Investigational
Countries:BelgiumBelgium
  • Participants:18–64 years · 65+ years
  • Substances:ADX-324
  • Sponsor:Adarx Pharmaceuticals Inc.

Hypersensitivity+1

Recruiting

A Study Testing Prolonged versus Single Dose Penicillin Challenge in Patients with Suspected Penicillin Allergy Using Amoxicillin

Investigational
Countries:BelgiumBelgium
  • Participants:18–64 years · 65+ years
  • Substances:Amoxicillin Trihydrate
  • Sponsor:Austin Health

Chronic inflammatory demyelinating polyradiculoneuropathy

Recruiting

A Study of IMVT-1402 in Adults with Chronic Inflammatory Demyelinating Polyneuropathy to Prevent Disease Relapse

Investigational
Countries:BelgiumBelgium
  • Participants:18–64 years · 65+ years
  • Substances:Imeroprubart
  • Sponsor:Immunovant Sciences GmbH

Non-small cell lung cancer metastatic

Recruiting

Study of Different Dosing Schedules of Osimertinib in Patients with EGFR Mutated Advanced or Metastatic Non-Small Cell Lung Cancer

Registered drugNo placebo
Countries:BelgiumBelgium
  • Participants:18–64 years · 65+ years
  • Substances:Osimertinib
  • Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

Endometrial cancer+1

Recruiting

A study comparing BNT323 with chemotherapy in patients with HER2-expressing recurrent endometrial cancer who received previous treatment

Registered drugNo placebo
Countries:BelgiumBelgium
  • Participants:18–64 years · 65+ years
  • Substances:DB-1303
  • Sponsor:BioNTech SE

Malignant mast cell neoplasm

Recruiting

Study of BNT326 alone and with BNT327 in patients with advanced solid tumors: Testing safety and effectiveness of new cancer treatments

InvestigationalNo placebo
Countries:BelgiumBelgium
  • Participants:18–64 years · 65+ years
  • Substances:BNT326
  • Sponsor:BioNTech SE

K-ras gene mutation+2

Recruiting

Study of divarasib and pembrolizumab compared to standard chemotherapy in previously untreated KRAS G12C-mutated advanced non-small cell lung cancer

Registered drugNo placebo
Countries:BelgiumBelgium
  • Participants:18–64 years · 65+ years
  • Substances:Budesonide
  • Sponsor:F. Hoffmann-La Roche AG

Colitis ulcerative+1

Recruiting

Study of MT-501 in patients with active Crohn's Disease or Ulcerative Colitis: A Phase 2 safety and effectiveness trial

Investigational
Countries:BelgiumBelgium
  • Participants:18–64 years · 65+ years
  • Substances:MT-201
  • Sponsor:Mirador Therapeutics Inc.

Chronic graft versus host disease

Recruiting

Study of axatilimab compared to standard therapy in children with chronic graft-versus-host disease who have previously received at least 2 treatments

InvestigationalNo placebo
Countries:BelgiumBelgium
  • Participants:0–17 years
  • Substances:Axatilimab
  • Sponsor:Incyte Corp.

Breast cancer+2

Recruiting

Study of PF-07248144 and fulvestrant in adults with hormone receptor-positive, HER2-negative advanced or metastatic breast cancer who had progression after CDK4/6 inhibitor therapy

Registered drugNo placebo
Countries:BelgiumBelgium
  • Participants:18–64 years · 65+ years
  • Substances:Everolimus
  • Sponsor:Pfizer Inc.

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Clinical research in Mechelen

What the registry says about research in the country

01 Respiratory Health Research

Current studies focus on respiratory infections and preventive measures, including innovative vaccine trials for RSV and influenza in various age groups. Research encompasses both standalone treatments and combination therapies.

  • RSV Vaccine Development
  • Influenza Prevention
  • COVID-19 Co-administration Studies

Special attention is given to protecting vulnerable populations, particularly adults over 60 years of age.

02 Oncology Studies

Groundbreaking research in lung cancer treatment, particularly focusing on non-small cell and small cell variants. Studies evaluate novel therapeutic approaches including immunotherapy combinations.

  • NSCLC Treatment Innovations
  • Lymphoma Therapies
  • Targeted Drug Development

Investigations include both first-line treatments and advanced therapy options.

03 Cardiovascular and Metabolic Research

Studies addressing cardiovascular disease and related conditions, including trials for hypertriglyceridemia and stroke prevention in atrial fibrillation patients.

  • Lipid Management
  • Stroke Prevention
  • Cardiovascular Risk Reduction

Focus on both preventive measures and treatment of existing conditions.

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