Clinical trials in Mainz – page 13

601 clinical trials in Mainz, Germany across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Mainz at a glance

601

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601 trials in Mainz

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Chronic lymphocytic leukaemia+3

Recruiting

Registered drugNo placebo

Study on the Safety and Effectiveness of AZD0486 Alone or with Other Drugs for Adults with Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Mantle Cell Lymphoma, or Large B-Cell Lymphoma

Registered drugNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:Acalabrutinib
Sponsor:AstraZeneca AB

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Cardiac function disturbance postoperative+1

Recruiting

Registered drugNo placebo

Study on Reducing Acute Kidney Injury After Heart Surgery Using Angiotensin II or Noradrenaline for Patients with Low Blood Pressure

Registered drugNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:ANGIOTENSIN II
Sponsor:Universitaet Muenster

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Chronic graft versus host disease

Recruiting

Registered drug

Study on Axatilimab and Corticosteroids for Initial Treatment of Chronic Graft-Versus-Host Disease in Patients

Registered drug

Germany

Participants:0–17 years · 18–64 years · 65+ years
Substances:Axatilimab
Sponsor:Incyte Corp.

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Study of Pembrolizumab and Lenvatinib for Patients with Advanced Vulvar Cancer Not Suitable for Surgery or Radiotherapy

Registered drugNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:Lenvatinib
Sponsor:AGO Research GmbH

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Malignant peritoneal neoplasm+2

Recruiting

Registered drugNo placebo

Comparison of Niraparib alone versus Niraparib with Bevacizumab in patients with newly diagnosed advanced ovarian cancer after chemotherapy with carboplatin and paclitaxel

Registered drugNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:Bevacizumab
Sponsor:AGO Research GmbH

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Study Comparing Amivantamab and Chemotherapy Versus Cetuximab and Chemotherapy for Patients with Advanced Colorectal Cancer

Registered drugNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:Amivantamab
Sponsor:Janssen - Cilag International

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Study on Ifinatamab Deruxtecan for Patients with Recurrent or Metastatic Solid Tumors

InvestigationalNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:Ifinatamab Deruxtecan
Sponsor:Daiichi Sankyo Inc.

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Study on the Safety and Effectiveness of Osimertinib and Datopotamab Deruxtecan for Patients with Advanced EGFR Mutation-Positive Non-Small Cell Lung Cancer

Registered drugNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:Osimertinib
Sponsor:AstraZeneca AB

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Study on the Safety and Tolerability of SNDX-5613 for Patients with Relapsed or Refractory Acute Leukemias

InvestigationalNo placebo

Germany

Participants:0–17 years · 18–64 years · 65+ years
Substances:Revumenib
Sponsor:Syndax Pharmaceuticals Inc.

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Study Comparing Elranatamab, Daratumumab, and Lenalidomide with Daratumumab, Lenalidomide, and Dexamethasone for Patients with Newly Diagnosed Multiple Myeloma

Registered drugNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:Bortezomib
Sponsor:Pfizer Inc.

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Study on Shortened Anticoagulation with Rivaroxaban for Blood Clot Prevention in Patients Undergoing Hip Replacement Surgery

Investigational

Germany

Participants:18–64 years · 65+ years
Substances:Rivaroxaban
Sponsor:Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR

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Study on High-Dose Chemotherapy with Cytarabine and Drug Combination for Elderly Patients with Primary CNS Lymphoma

Registered drugNo placebo

Germany

Participants:65+ years
Substances:Busulfan
Sponsor:Medical Center - University Of Freiburg

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Clinical research in Mainz

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01 Infectious Disease Prevention

Groundbreaking trials focusing on viral infections including studies of vaccines against Respiratory Syncytial Virus, Herpes Zoster, and Cytomegalovirus. Research aims to evaluate vaccine efficacy and immune response in different age groups.

RSV and hMPV Prevention
Herpes Zoster Protection
CMV Vaccine Development

Special attention is given to protecting vulnerable populations, including older adults and those at increased risk.

02 Oncology Research

Innovative clinical trials targeting various forms of cancer, including studies on breast cancer, pancreatic cancer, and multiple myeloma. Research focuses on novel therapeutic approaches and combination treatments.

Advanced Breast Cancer Therapy
Gastric Cancer Treatment
Lymphoma Management

Emphasis on personalized medicine approaches and targeted therapies for better patient outcomes.

03 Chronic Disease Management

Comprehensive studies addressing respiratory conditions, autoimmune disorders, and metabolic diseases. Research includes treatments for asthma, multiple sclerosis, and obesity.

Pulmonary Hypertension
Chronic Kidney Disease
Autoimmune Conditions

Focus on developing long-term treatment solutions and improving quality of life for patients.

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