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Clinical trials in Lyon – page 50

1 204 clinical trials in Lyon, France across 7 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Lyon at a glance
1 204
clinical trials
  • Research sites7
Type of trial
Recruitment status
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1 204 trials in Lyon

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Cervical dysplasia

Not yet recruiting

Testing HPV Vaccine to Prevent Return of Precancerous Lesions in Patients Treated for High-Grade Abnormal Cell Changes Caused by HPV

Registered drug
Countries:FranceFrance
  • Participants:18–64 years
  • Substances:Polysorbate 80
  • Sponsor:Institut Gustave Roussy

Acute lymphocytic leukaemia+2

Not yet recruiting

A Study of Blinatumomab in Children with Relapsed or Treatment-Resistant B Cell Acute Lymphoblastic Leukemia with Remaining Disease Traces

InvestigationalNo placebo
Countries:FranceFrance
  • Participants:0–17 years
  • Substances:Blinatumomab
  • Sponsor:Amgen Inc.

Rectal adenocarcinoma

Not yet recruiting

Study of drug combination with radiotherapy versus radiotherapy alone for locally advanced rectal cancer in patients 75 years and older

Registered drugNo placebo
Countries:FranceFrance
  • Participants:65+ years
  • Substances:Calcium Levofolinate
  • Sponsor:Unicancer

Testing avacopan added to standard treatment in patients with ANCA-associated vasculitis with severe kidney damage

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Avacopan
  • Sponsor:Centre Hospitalier Universitaire De Toulouse
Countries:FranceFrance
  • Participants:18–64 years
  • Substances:Adalimumab
  • Sponsor:Assistance Publique Hopitaux De Paris

Back pain

Not yet recruiting

Study of Ropivacaine and Dexamethasone Nerve Block for Patients with Acute Low Back Pain

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Ketoprofen
  • Sponsor:Centre Hospitalier Universitaire De Montpellier

Study of pirtobrutinib combined with immuno-chemotherapy for previously untreated patients with symptomatic chronic lymphocytic leukemia

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Pirtobrutinib
  • Sponsor:French Innovative Leukemia Organization (F.I.L.O.).

K-ras gene mutation+2

Not yet recruiting

Study of divarasib and pembrolizumab compared to standard chemotherapy in previously untreated KRAS G12C-mutated advanced non-small cell lung cancer

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Budesonide
  • Sponsor:F. Hoffmann-La Roche AG

Deafness

Not yet recruiting

Study of Aspirin and Folic Acid Treatment for Patients with Sudden Sensorineural Hearing Loss

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Acetylsalicylic Acid
  • Sponsor:Assistance Publique Hopitaux De Paris

Non-small cell lung cancer

Not yet recruiting

Study of zipalertinib plus chemotherapy versus placebo plus chemotherapy in patients with stage IB-IIIA non-small cell lung cancer with uncommon EGFR mutations after surgery

Registered drug
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Carboplatin
  • Sponsor:Taiho Oncology Inc.

Erysipelas

Not yet recruiting

Comparison of compression therapy alone versus compression therapy with phenoxymethylpenicillin for preventing recurrent erysipelas in lower limbs

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Phenoxymethylpenicillin
  • Sponsor:Centre Hospitalier Regional Universitaire De Tours

Cardiac arrest

Not yet recruiting

Study comparing low-dose versus standard-dose epinephrine for better brain recovery in patients with out-of-hospital cardiac arrest

Registered drugNo placebo
Countries:FranceFrance
  • Participants:18–64 years · 65+ years
  • Substances:Epinephrine Bitartrate
  • Sponsor:CHRU De Nancy

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Clinical research in Lyon

What the registry says about research in the country

01 Oncology Research

Innovative clinical trials focusing on advanced cancer treatments, including studies for endometrial carcinoma, bladder cancer, and various solid tumors. Current research explores combination therapies with novel immunotherapy approaches.

  • Triple-negative breast cancer treatments
  • Gastric and esophageal cancer therapies
  • Advanced pancreatic adenocarcinoma

Multiple studies are evaluating targeted therapies and immunological approaches for various tumor types.

02 Immunology and Infectious Diseases

Groundbreaking research in immune system modulation and infectious disease prevention, including studies on COVID-19 vaccines and immune response in critical conditions.

  • Novel COVID-19 intranasal vaccine development
  • Yellow fever vaccine studies
  • ICU-acquired immunosuppression treatment

Focus on developing innovative vaccination strategies and immune system interventions.

03 Chronic Conditions

Studies addressing long-term health conditions, with particular emphasis on kidney disease, cardiovascular health, and metabolic disorders.

  • Chronic kidney disease management
  • Heart failure prevention
  • Hypertriglyceridemia treatment

Innovative approaches combining established and experimental treatments for improved patient outcomes.

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