Clinical trials in Leidschendam – page 78

1 919 clinical trials in Leidschendam, The Netherlands across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Leidschendam at a glance

1 919

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1 919 trials in Leidschendam

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Allogenic stem cell transplantation

Not yet recruiting

Study of UM171-expanded cord blood transplantation for patients with high-risk and very high-risk acute leukemia or myelodysplasia

InvestigationalNo placebo

Study of UM171-expanded cord blood transplantation for patients with high-risk and very high-risk acute leukemia or myelodysplasia

InvestigationalNo placebo

The Netherlands

Participants:18–64 years
Substances:Dorocubicel
Sponsor:Excellthera Inc.

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Skin cancer+1

Not yet recruiting

Study of DYP688 for Patients with Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas

InvestigationalNo placebo

Study of DYP688 for Patients with Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:DYP688
Sponsor:Novartis Pharma AG

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Heart disease congenital+1

Not yet recruiting

Study on Allopurinol Sodium for Brain Injury Prevention in Newborns with Critical Congenital Heart Disease Undergoing Heart Surgery

Registered drug

Study on Allopurinol Sodium for Brain Injury Prevention in Newborns with Critical Congenital Heart Disease Undergoing Heart Surgery

Registered drug

The Netherlands

Participants:0–17 years
Substances:Allopurinol Sodium
Sponsor:Universitair Medisch Centrum Utrecht

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Acute myeloid leukaemia+2

Not yet recruiting

Study of EP0042 alone and in combination with venetoclax and azacitidine in patients with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), or chronic myelomonocytic leukemia (CMML)

Registered drugNo placebo

Study of EP0042 alone and in combination with venetoclax and azacitidine in patients with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), or chronic myelomonocytic leukemia (CMML)

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Azacitidine
Sponsor:Ellipses Pharma Limited

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COVID-19

Not yet recruiting

Study on Metformin and Colchicine for Treating Long COVID Symptoms in Patients

Registered drugNo placebo

Study on Metformin and Colchicine for Treating Long COVID Symptoms in Patients

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Colchicine
Sponsor:Universitair Medisch Centrum Utrecht

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Pancreatic carcinoma

Not yet recruiting

Study of perioperative versus post-surgery FOLFIRINOX (irinotecan, oxaliplatin, fluorouracil, and folinic acid) treatment in patients with resectable pancreatic cancer

Registered drugNo placebo

Study of perioperative versus post-surgery FOLFIRINOX (irinotecan, oxaliplatin, fluorouracil, and folinic acid) treatment in patients with resectable pancreatic cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Fluorouracil
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Neurofibromatosis

Not yet recruiting

Study on Trametinib for Patients with Neurofibromatosis Type 1 and Symptomatic Plexiform Neurofibromas

Registered drugNo placebo

Study on Trametinib for Patients with Neurofibromatosis Type 1 and Symptomatic Plexiform Neurofibromas

Registered drugNo placebo

The Netherlands

Participants:18–64 years
Substances:Trametinib
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Coronary artery disease

Not yet recruiting

Study on Ticagrelor and Clopidogrel for Patients with Coronary Artery Disease Undergoing PCI

Registered drugNo placebo

Study on Ticagrelor and Clopidogrel for Patients with Coronary Artery Disease Undergoing PCI

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Clopidogrel
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Systemic lupus erythematosus+1

Not yet recruiting

Study on the Effects of Rapcabtagene Autoleucel in Patients with Systemic Lupus Erythematosus and Active, Refractory Lupus Nephritis

Registered drugNo placebo

Study on the Effects of Rapcabtagene Autoleucel in Patients with Systemic Lupus Erythematosus and Active, Refractory Lupus Nephritis

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Azathioprine
Sponsor:Novartis Pharma AG

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Atrial fibrillation

Not yet recruiting

Study on Teprenone for Preventing Atrial Fibrillation After Heart Surgery in Patients

Registered drug

Study on Teprenone for Preventing Atrial Fibrillation After Heart Surgery in Patients

Registered drug

The Netherlands

Participants:18–64 years
Substances:Teprenone
Sponsor:Amsterdam UMC Stichting

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Systemic scleroderma

Not yet recruiting

Study comparing rapcabtagene autoleucel and rituximab in patients with severe refractory diffuse cutaneous systemic sclerosis

Registered drugNo placebo

Study comparing rapcabtagene autoleucel and rituximab in patients with severe refractory diffuse cutaneous systemic sclerosis

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Cyclophosphamide
Sponsor:Novartis Pharma AG

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Colorectal cancer metastatic+2

Not yet recruiting

Study on the Effectiveness of Floxuridine in Patients with Resectable Colorectal Liver Metastases and Low Clinical Risk Score

Registered drugNo placebo

Study on the Effectiveness of Floxuridine in Patients with Resectable Colorectal Liver Metastases and Low Clinical Risk Score

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

Contact Research Centre

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Clinical research in Leidschendam

What the registry says about research in the country

01 Oncology - Lung Cancer Research

Multiple clinical trials focusing on non-small cell lung cancer (NSCLC) treatment advancements, evaluating novel therapeutic approaches including immunotherapy combinations and targeted treatments.

Advanced NSCLC treatments
Immunotherapy combinations
KRAS G12C inhibitors

Studies compare various treatment options to improve patient outcomes and survival rates.

02 Breast Cancer Studies

Comprehensive research into breast cancer treatments, particularly focusing on hormone receptor-positive and HER2-positive subtypes, investigating targeted therapies and chemotherapy combinations.

Metastatic breast cancer
HER2-positive therapy
Triple-negative breast cancer

Trials examine innovative treatment strategies and personalized approaches.

03 Hematologic Malignancies

Studies focusing on lymphoma treatments, including both Hodgkin and non-Hodgkin variants, evaluating response-adapted therapies and novel drug combinations.

Advanced Hodgkin Lymphoma
Follicular Lymphoma
Treatment optimization

Research aims to improve treatment outcomes while minimizing toxicity.

04 Gastrointestinal Oncology

Investigations into colorectal cancer and related conditions, including innovative surgical approaches and treatment strategies for recurrent disease.

Rectal cancer treatments
Esophagogastric cancer
Surgical innovations

Focus on improving surgical outcomes and treatment effectiveness.

05 Brain Metastases Research

Studies examining treatment options for cerebral radiation necrosis and brain metastases, including innovative detection methods and therapeutic approaches.

Radiation necrosis treatment
Metastatic detection
Targeted therapies

Research aims to improve detection and treatment of brain metastases.

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