Clinical trials in Leidschendam – page 70

1 919 clinical trials in Leidschendam, The Netherlands across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Leidschendam at a glance

1 919

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1 919 trials in Leidschendam

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Idiopathic pulmonary fibrosis

Not yet recruiting

Randomized Phase 3 Study of Deupirfenidone (LYT‑100) versus Pirfenidone in Adults with Idiopathic Pulmonary Fibrosis

Registered drugNo placebo

Randomized Phase 3 Study of Deupirfenidone (LYT‑100) versus Pirfenidone in Adults with Idiopathic Pulmonary Fibrosis

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Deupirfenidone
Sponsor:Celea Therapeutics Inc.

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Choroid melanoma

Not yet recruiting

Long‑Term Follow‑Up Study of Belzupacap Sarotalocan in Patients with Early Choroidal Melanoma

Investigational

Long‑Term Follow‑Up Study of Belzupacap Sarotalocan in Patients with Early Choroidal Melanoma

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:Aura Biosciences Inc.

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Optic ischaemic neuropathy

Not yet recruiting

Efficacy and Safety of Intranasal Cenegermin in Adults with Non‑Arteritic Anterior Ischemic Optic Neuropathy (NAION)

Investigational

Efficacy and Safety of Intranasal Cenegermin in Adults with Non‑Arteritic Anterior Ischemic Optic Neuropathy (NAION)

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:Cenegermin
Sponsor:Dompe' Farmaceutici S.p.A.

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Diffuse large B-cell lymphoma

Not yet recruiting

Epcoritamab plus rituximab versus rituximab alone in elderly, frail or unfit patients with newly diagnosed diffuse large B‑cell lymphoma

Registered drugNo placebo

Epcoritamab plus rituximab versus rituximab alone in elderly, frail or unfit patients with newly diagnosed diffuse large B‑cell lymphoma

Registered drugNo placebo

The Netherlands

Participants:65+ years
Substances:Epcoritamab
Sponsor:Hemato-Oncologie voor Volwassenen Nederland (Hovon) Stichting

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Acute myeloid leukaemia+2

Not yet recruiting

Safety and tolerability study of S-241656 with posaconazole in patients with AML, MDS/AML or CMML

Registered drugNo placebo

Safety and tolerability study of S-241656 with posaconazole in patients with AML, MDS/AML or CMML

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Posaconazole
Sponsor:Institut De Recherches Internationales Servier IRIS

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Neoplasm

Not yet recruiting

Long‑term Safety of Adagrasib with Drug Combination in Adults with Solid Tumors

Registered drugNo placebo

Long‑term Safety of Adagrasib with Drug Combination in Adults with Solid Tumors

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Adagrasib
Sponsor:Bristol-Myers Squibb Services Unlimited Company

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Post-traumatic stress disorder

Not yet recruiting

Study of MDMA hydrochloride therapy in adolescents aged 16‑18 with treatment‑resistant post‑traumatic stress disorder

InvestigationalNo placebo

Study of MDMA hydrochloride therapy in adolescents aged 16‑18 with treatment‑resistant post‑traumatic stress disorder

InvestigationalNo placebo

The Netherlands

Participants:0–17 years
Sponsor:Amsterdam UMC Stichting

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Small cell lung cancer limited stage

Not yet recruiting

Durvalumab after chemoradiation for patients with limited‑stage small cell lung cancer: a randomized trial of high‑dose versus standard thoracic radiation

Registered drugNo placebo

Durvalumab after chemoradiation for patients with limited‑stage small cell lung cancer: a randomized trial of high‑dose versus standard thoracic radiation

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Durvalumab
Sponsor:Norwegian University Of Science And Technolology

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Heart failure with reduced ejection fraction

Not yet recruiting

Evaluating the efficacy and safety of CRD-4730 in patients with heart failure with reduced ejection fraction

Investigational

Evaluating the efficacy and safety of CRD-4730 in patients with heart failure with reduced ejection fraction

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:CRD-4730
Sponsor:Cardurion Pharmaceuticals Inc.

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Barth syndrome

Not yet recruiting

Efficacy and Safety of Daily Subcutaneous Elamipretide Trihydrochloride Injections in Patients with Barth Syndrome (Phase 3b/4 Randomized Trial)

Investigational

Efficacy and Safety of Daily Subcutaneous Elamipretide Trihydrochloride Injections in Patients with Barth Syndrome (Phase 3b/4 Randomized Trial)

Investigational

The Netherlands

Participants:0–17 years · 18–64 years · 65+ years
Sponsor:Stealth Biotherapeutics Inc.

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Gastric cancer+1

Not yet recruiting

Capecitabine drug combination in perioperative treatment for patients with gastric and esophageal cancer

Registered drugNo placebo

Capecitabine drug combination in perioperative treatment for patients with gastric and esophageal cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Capecitabine
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Squamous cell carcinoma of the oral cavity+1

Not yet recruiting

Study of neoadjuvant intratumoral ipilimumab combined with systemic nivolumab in patients with locally advanced resectable oral cavity squamous cell carcinoma

Registered drugNo placebo

Study of neoadjuvant intratumoral ipilimumab combined with systemic nivolumab in patients with locally advanced resectable oral cavity squamous cell carcinoma

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Ipilimumab
Sponsor:Amsterdam UMC Stichting

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Clinical research in Leidschendam

What the registry says about research in the country

01 Oncology - Lung Cancer Research

Multiple clinical trials focusing on non-small cell lung cancer (NSCLC) treatment advancements, evaluating novel therapeutic approaches including immunotherapy combinations and targeted treatments.

Advanced NSCLC treatments
Immunotherapy combinations
KRAS G12C inhibitors

Studies compare various treatment options to improve patient outcomes and survival rates.

02 Breast Cancer Studies

Comprehensive research into breast cancer treatments, particularly focusing on hormone receptor-positive and HER2-positive subtypes, investigating targeted therapies and chemotherapy combinations.

Metastatic breast cancer
HER2-positive therapy
Triple-negative breast cancer

Trials examine innovative treatment strategies and personalized approaches.

03 Hematologic Malignancies

Studies focusing on lymphoma treatments, including both Hodgkin and non-Hodgkin variants, evaluating response-adapted therapies and novel drug combinations.

Advanced Hodgkin Lymphoma
Follicular Lymphoma
Treatment optimization

Research aims to improve treatment outcomes while minimizing toxicity.

04 Gastrointestinal Oncology

Investigations into colorectal cancer and related conditions, including innovative surgical approaches and treatment strategies for recurrent disease.

Rectal cancer treatments
Esophagogastric cancer
Surgical innovations

Focus on improving surgical outcomes and treatment effectiveness.

05 Brain Metastases Research

Studies examining treatment options for cerebral radiation necrosis and brain metastases, including innovative detection methods and therapeutic approaches.

Radiation necrosis treatment
Metastatic detection
Targeted therapies

Research aims to improve detection and treatment of brain metastases.

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