Clinical trials in Leidschendam – page 60

1 919 clinical trials in Leidschendam, The Netherlands across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Leidschendam at a glance

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1 919 trials in Leidschendam

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Acute myeloid leukaemia

Recruiting

Study on the Safety and Effectiveness of Quizartinib for Children with Newly Diagnosed FLT3-ITD Positive AML and Normal NPM1

InvestigationalNo placebo

Study on the Safety and Effectiveness of Quizartinib for Children with Newly Diagnosed FLT3-ITD Positive AML and Normal NPM1

InvestigationalNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Quizartinib Dihydrochloride
Sponsor:Prinses Maxima Centrum voor Kinderoncologie B.V.

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Neurodevelopmental disorder

Recruiting

Study on the Safety and Effects of Radiprodil for Children with GRIN-related Disorder

Investigational

Study on the Safety and Effects of Radiprodil for Children with GRIN-related Disorder

Investigational

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Radiprodil
Sponsor:Grin Therapeutics Inc.

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Lymphangioma

Recruiting

Study on Alpelisib for Treating Lymphatic Malformations in Patients with PIK3CA Mutation

Investigational

Study on Alpelisib for Treating Lymphatic Malformations in Patients with PIK3CA Mutation

Investigational

The Netherlands

Participants:0–17 years · 18–64 years · 65+ years
Substances:Alpelisib
Sponsor:Novartis Pharma AG

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Oesophageal atresia

Recruiting

Study on Triamcinolone Acetonide Injections to Prevent Esophageal Strictures in Children with Esophageal Atresia

Registered drugNo placebo

Study on Triamcinolone Acetonide Injections to Prevent Esophageal Strictures in Children with Esophageal Atresia

Registered drugNo placebo

The Netherlands

Participants:0–17 years
Substances:Triamcinolone Acetonide
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Chronic lymphocytic leukaemia+1

Recruiting

Study on Venetoclax and Epcoritamab for Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

InvestigationalNo placebo

Study on Venetoclax and Epcoritamab for Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Epcoritamab
Sponsor:Hemato-Oncologie voor Volwassenen Nederland (Hovon) Stichting

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Neuroendocrine tumour

Recruiting

Study on the Effect of Octreotide and Lanreotide in Peptide Receptor Radionuclide Therapy for Adults with Neuroendocrine Tumors

Registered drugNo placebo

Study on the Effect of Octreotide and Lanreotide in Peptide Receptor Radionuclide Therapy for Adults with Neuroendocrine Tumors

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Lanreotide
Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

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Triple negative breast cancer

Recruiting

Study on Immunotherapy with Atezolizumab, Tiragolumab, and Ipilimumab for Patients with Advanced Triple Negative Breast Cancer

Registered drugNo placebo

Study on Immunotherapy with Atezolizumab, Tiragolumab, and Ipilimumab for Patients with Advanced Triple Negative Breast Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Atezolizumab
Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

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Crohn's disease

Recruiting

Study on Crohn's Disease: Evaluating Risankizumab's Effects in Children Aged 2 to 17 with Moderate to Severe Symptoms

Investigational

Study on Crohn's Disease: Evaluating Risankizumab's Effects in Children Aged 2 to 17 with Moderate to Severe Symptoms

Investigational

The Netherlands

Participants:0–17 years
Substances:Risankizumab
Sponsor:AbbVie Deutschland GmbH & Co. KG

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ABO haemolytic disease of newborn

Recruiting

Study of Nipocalimab in Pregnant Women at Risk of Severe Hemolytic Disease of the Fetus and Newborn (HDFN)

Investigational

Study of Nipocalimab in Pregnant Women at Risk of Severe Hemolytic Disease of the Fetus and Newborn (HDFN)

Investigational

The Netherlands

Participants:18–64 years
Substances:Nipocalimab
Sponsor:Janssen Cilag International

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Endometriosis

Recruiting

Study on Esketamine for Treating Chronic Pain in Endometriosis Patients

Registered drug

Study on Esketamine for Treating Chronic Pain in Endometriosis Patients

Registered drug

The Netherlands

Participants:18–64 years
Substances:Ondansetron
Sponsor:Reinier de Graaf Groep

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Chronic inflammatory demyelinating polyradiculoneuropathy

Recruiting

Study on Long-term Safety and Efficacy of Efgartigimod PH20 SC in Adults with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

InvestigationalNo placebo

Study on Long-term Safety and Efficacy of Efgartigimod PH20 SC in Adults with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Efgartigimod Alfa
Sponsor:Argenx

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Corneal transplant+2

Recruiting

Study on Dexamethasone and Fluorometholone for Patients Undergoing Corneal Transplantation

Registered drugNo placebo

Study on Dexamethasone and Fluorometholone for Patients Undergoing Corneal Transplantation

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Dexamethasone
Sponsor:University Hospital Maastricht

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Clinical research in Leidschendam

What the registry says about research in the country

01 Oncology - Lung Cancer Research

Multiple clinical trials focusing on non-small cell lung cancer (NSCLC) treatment advancements, evaluating novel therapeutic approaches including immunotherapy combinations and targeted treatments.

Advanced NSCLC treatments
Immunotherapy combinations
KRAS G12C inhibitors

Studies compare various treatment options to improve patient outcomes and survival rates.

02 Breast Cancer Studies

Comprehensive research into breast cancer treatments, particularly focusing on hormone receptor-positive and HER2-positive subtypes, investigating targeted therapies and chemotherapy combinations.

Metastatic breast cancer
HER2-positive therapy
Triple-negative breast cancer

Trials examine innovative treatment strategies and personalized approaches.

03 Hematologic Malignancies

Studies focusing on lymphoma treatments, including both Hodgkin and non-Hodgkin variants, evaluating response-adapted therapies and novel drug combinations.

Advanced Hodgkin Lymphoma
Follicular Lymphoma
Treatment optimization

Research aims to improve treatment outcomes while minimizing toxicity.

04 Gastrointestinal Oncology

Investigations into colorectal cancer and related conditions, including innovative surgical approaches and treatment strategies for recurrent disease.

Rectal cancer treatments
Esophagogastric cancer
Surgical innovations

Focus on improving surgical outcomes and treatment effectiveness.

05 Brain Metastases Research

Studies examining treatment options for cerebral radiation necrosis and brain metastases, including innovative detection methods and therapeutic approaches.

Radiation necrosis treatment
Metastatic detection
Targeted therapies

Research aims to improve detection and treatment of brain metastases.

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