Clinical trials in Leidschendam – page 54

1 919 clinical trials in Leidschendam, The Netherlands across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Leidschendam at a glance

1 919

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1 919 trials in Leidschendam

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Plasma cell myeloma

Recruiting

Comparison of belantamab mafodotin, bortezomib and dexamethasone versus daratumumab, bortezomib and dexamethasone in patients with relapsed/refractory multiple myeloma

Registered drugNo placebo

Comparison of belantamab mafodotin, bortezomib and dexamethasone versus daratumumab, bortezomib and dexamethasone in patients with relapsed/refractory multiple myeloma

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Belantamab Mafodotin
Sponsor:Glaxosmithkline Research & Development Limited

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Myelofibrosis+1

Recruiting

Study on the Effectiveness and Safety of Selinexor for Patients with Myelofibrosis and Moderate Thrombocytopenia Who Have Not Used JAK Inhibitors

Registered drugNo placebo

Study on the Effectiveness and Safety of Selinexor for Patients with Myelofibrosis and Moderate Thrombocytopenia Who Have Not Used JAK Inhibitors

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Aprepitant
Sponsor:Karyopharm Therapeutics Inc.

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Andersen-Tawil syndrome+1

Recruiting

Study of flecainide alone or with beta-blockers or calcium channel blockers and quinidine for treating ventricular arrhythmias in patients with Andersen-Tawil syndrome and MEPPC

Registered drugNo placebo

Study of flecainide alone or with beta-blockers or calcium channel blockers and quinidine for treating ventricular arrhythmias in patients with Andersen-Tawil syndrome and MEPPC

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Atenolol
Sponsor:Amsterdam UMC Stichting

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Dementia Alzheimer's type

Recruiting

Study on Efavirenz for Patients with Early Alzheimer's Disease

Investigational

Study on Efavirenz for Patients with Early Alzheimer's Disease

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:Efavirenz
Sponsor:Amsterdam UMC Stichting

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Non-small cell lung cancer

Recruiting

Study of RMC-6291 and Pembrolizumab with or without Chemotherapy for Patients with Advanced KRAS G12C Mutated Lung Cancer

Registered drugNo placebo

Study of RMC-6291 and Pembrolizumab with or without Chemotherapy for Patients with Advanced KRAS G12C Mutated Lung Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Carboplatin
Sponsor:Revolution Medicines Inc.

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HIV infection

Recruiting

Study on Topiramate for Reactivating Hidden HIV in Patients with HIV on Antiretroviral Therapy

Registered drugNo placebo

Study on Topiramate for Reactivating Hidden HIV in Patients with HIV on Antiretroviral Therapy

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Topiramate
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Non-small cell lung cancer+2

Recruiting

Study on Preoperative Treatment with Amivantamab, Carboplatin, and Pemetrexed for Patients with Resectable Non-Small-Cell Lung Cancer with EGFR Mutations

Registered drugNo placebo

Study on Preoperative Treatment with Amivantamab, Carboplatin, and Pemetrexed for Patients with Resectable Non-Small-Cell Lung Cancer with EGFR Mutations

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Amivantamab
Sponsor:Universitaetsklinikum Essen AöR

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Myasthenia gravis

Recruiting

Study on the Safety and Effectiveness of NMD670 for Adults with Myasthenia Gravis

Investigational

Study on the Safety and Effectiveness of NMD670 for Adults with Myasthenia Gravis

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:NMD670
Sponsor:NMD Pharma A/S

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Chronic lymphocytic leukaemia+1

Recruiting

Long-Term Safety Study of BCMACP03, BCN-CP01, and 19CP02 for Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma, CLL, SLL, or Multiple Myeloma

InvestigationalNo placebo

Long-Term Safety Study of BCMACP03, BCN-CP01, and 19CP02 for Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma, CLL, SLL, or Multiple Myeloma

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:Lakefront Biotherapeutics

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Neuroblastoma+1

Recruiting

Study on Dinutuximab Beta with Chemotherapy for Children and Teens with Newly Diagnosed High-Risk Neuroblastoma

Registered drugNo placebo

Study on Dinutuximab Beta with Chemotherapy for Children and Teens with Newly Diagnosed High-Risk Neuroblastoma

Registered drugNo placebo

The Netherlands

Participants:0–17 years
Substances:Dinutuximab Beta
Sponsor:Prinses Maxima Centrum voor Kinderoncologie B.V.

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Glomerulonephritis minimal lesion+3

Recruiting

Study on the Safety and Effects of Sparsentan for Children with Proteinuric Kidney Diseases

InvestigationalNo placebo

Study on the Safety and Effects of Sparsentan for Children with Proteinuric Kidney Diseases

InvestigationalNo placebo

The Netherlands

Participants:0–17 years
Substances:Sparsentan
Sponsor:Travere Therapeutics Inc.

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Myasthenia gravis

Recruiting

Study on Efgartigimod for Children Aged 2-17 with Generalized Myasthenia Gravis

Registered drugNo placebo

Study on Efgartigimod for Children Aged 2-17 with Generalized Myasthenia Gravis

Registered drugNo placebo

The Netherlands

Participants:0–17 years
Substances:Efgartigimod Alfa
Sponsor:Argenx

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Clinical research in Leidschendam

What the registry says about research in the country

01 Oncology - Lung Cancer Research

Multiple clinical trials focusing on non-small cell lung cancer (NSCLC) treatment advancements, evaluating novel therapeutic approaches including immunotherapy combinations and targeted treatments.

Advanced NSCLC treatments
Immunotherapy combinations
KRAS G12C inhibitors

Studies compare various treatment options to improve patient outcomes and survival rates.

02 Breast Cancer Studies

Comprehensive research into breast cancer treatments, particularly focusing on hormone receptor-positive and HER2-positive subtypes, investigating targeted therapies and chemotherapy combinations.

Metastatic breast cancer
HER2-positive therapy
Triple-negative breast cancer

Trials examine innovative treatment strategies and personalized approaches.

03 Hematologic Malignancies

Studies focusing on lymphoma treatments, including both Hodgkin and non-Hodgkin variants, evaluating response-adapted therapies and novel drug combinations.

Advanced Hodgkin Lymphoma
Follicular Lymphoma
Treatment optimization

Research aims to improve treatment outcomes while minimizing toxicity.

04 Gastrointestinal Oncology

Investigations into colorectal cancer and related conditions, including innovative surgical approaches and treatment strategies for recurrent disease.

Rectal cancer treatments
Esophagogastric cancer
Surgical innovations

Focus on improving surgical outcomes and treatment effectiveness.

05 Brain Metastases Research

Studies examining treatment options for cerebral radiation necrosis and brain metastases, including innovative detection methods and therapeutic approaches.

Radiation necrosis treatment
Metastatic detection
Targeted therapies

Research aims to improve detection and treatment of brain metastases.

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