Clinical trials in Leidschendam – page 43

1 919 clinical trials in Leidschendam, The Netherlands across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Leidschendam at a glance

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1 919 trials in Leidschendam

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Uveal melanoma

Recruiting

Study of ipilimumab, nivolumab and melphalan combination therapy with hepatic perfusion in patients with advanced uveal melanoma that has spread to other organs

Registered drugNo placebo

Study of ipilimumab, nivolumab and melphalan combination therapy with hepatic perfusion in patients with advanced uveal melanoma that has spread to other organs

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Ipilimumab
Sponsor:Leids Universitair Medisch Centrum (LUMC)

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Chronic myeloid leukaemia

Recruiting

Study on Stopping Dasatinib in Patients with Chronic Myeloid Leukemia After a Previous Attempt to Stop Treatment

Registered drugNo placebo

Study on Stopping Dasatinib in Patients with Chronic Myeloid Leukemia After a Previous Attempt to Stop Treatment

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Dasatinib
Sponsor:Region Uppsala

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Uveal melanoma

Recruiting

Title: Comparing tebentafusp treatment versus observation in patients with high-risk eye melanoma (uveal melanoma) after initial treatment

Registered drugNo placebo

Title: Comparing tebentafusp treatment versus observation in patients with high-risk eye melanoma (uveal melanoma) after initial treatment

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Tebentafusp
Sponsor:European Organisation For Research And Treatment Of Cancer

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Non-small cell lung cancer+1

Recruiting

Study of Durvalumab, Tremelimumab, Chemotherapy, and Radiotherapy for Patients with Newly Diagnosed Non-Small Cell Lung Cancer with Limited Spread

Registered drugNo placebo

Study of Durvalumab, Tremelimumab, Chemotherapy, and Radiotherapy for Patients with Newly Diagnosed Non-Small Cell Lung Cancer with Limited Spread

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Durvalumab
Sponsor:ETOP IBCSG Partners Foundation

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Cystic fibrosis

Recruiting

Study of VX-121, Tezacaftor, and Deutivacaftor for Children Aged 1-11 with Cystic Fibrosis

Registered drugNo placebo

Study of VX-121, Tezacaftor, and Deutivacaftor for Children Aged 1-11 with Cystic Fibrosis

Registered drugNo placebo

The Netherlands

Participants:0–17 years
Substances:Elexacaftor
Sponsor:Vertex Pharmaceuticals Inc.

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Acute myocardial infarction

Recruiting

Study on the Safety of Ticagrelor and Aspirin in Patients with ST-Elevation Myocardial Infarction After Heart Procedure

Registered drugNo placebo

Study on the Safety of Ticagrelor and Aspirin in Patients with ST-Elevation Myocardial Infarction After Heart Procedure

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Acetylsalicylic Acid
Sponsor:Stichting Radboud University Medical Center

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Pulmonary fibrosis

Recruiting

Study on PET/CT Imaging with [18F]-AlF-FAPI-74 for Identifying Fibrosis and Inflammation in Patients with Progressive Pulmonary Fibrosis

InvestigationalNo placebo

Study on PET/CT Imaging with [18F]-AlF-FAPI-74 for Identifying Fibrosis and Inflammation in Patients with Progressive Pulmonary Fibrosis

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:St. Antonius Ziekenhuis

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Neuroblastoma

Recruiting

Study Comparing [18F]meta-fluorobenzylguanidine PET-CT and Iodine (123I) Iobenguane Scans for Detecting Neuroblastoma in Patients

Registered drugNo placebo

Study Comparing [18F]meta-fluorobenzylguanidine PET-CT and Iodine (123I) Iobenguane Scans for Detecting Neuroblastoma in Patients

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Sponsor:Prinses Maxima Centrum voor Kinderoncologie B.V.

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Subdural haematoma

Recruiting

Study on Tranexamic Acid to Prevent Surgery in Patients with Chronic Subdural Hematoma

Registered drug

Study on Tranexamic Acid to Prevent Surgery in Patients with Chronic Subdural Hematoma

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Tranexamic Acid
Sponsor:Amsterdam UMC Stichting

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Foetal exposure during pregnancy+2

Recruiting

Study of Metformin to Extend Pregnancy Duration in Women with Preterm Preeclampsia

Registered drug

Study of Metformin to Extend Pregnancy Duration in Women with Preterm Preeclampsia

Registered drug

The Netherlands

Participants:18–64 years
Substances:Metformin Hydrochloride
Sponsor:Amsterdam UMC Stichting

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Fibrodysplasia ossificans progressiva

Recruiting

Study on the Effectiveness of INCB000928 for Patients with Fibrodysplasia Ossificans Progressiva

Investigational

Study on the Effectiveness of INCB000928 for Patients with Fibrodysplasia Ossificans Progressiva

Investigational

The Netherlands

Participants:0–17 years · 18–64 years · 65+ years
Substances:INCB000928
Sponsor:Incyte Corp.

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Medulloblastoma

Recruiting

Study on Medulloblastoma Treatment in Children Aged 3-5 Using Carboplatin and Drug Combination

Registered drugNo placebo

Study on Medulloblastoma Treatment in Children Aged 3-5 Using Carboplatin and Drug Combination

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Carboplatin
Sponsor:University Medical Center Hamburg-Eppendorf

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Clinical research in Leidschendam

What the registry says about research in the country

01 Oncology - Lung Cancer Research

Multiple clinical trials focusing on non-small cell lung cancer (NSCLC) treatment advancements, evaluating novel therapeutic approaches including immunotherapy combinations and targeted treatments.

Advanced NSCLC treatments
Immunotherapy combinations
KRAS G12C inhibitors

Studies compare various treatment options to improve patient outcomes and survival rates.

02 Breast Cancer Studies

Comprehensive research into breast cancer treatments, particularly focusing on hormone receptor-positive and HER2-positive subtypes, investigating targeted therapies and chemotherapy combinations.

Metastatic breast cancer
HER2-positive therapy
Triple-negative breast cancer

Trials examine innovative treatment strategies and personalized approaches.

03 Hematologic Malignancies

Studies focusing on lymphoma treatments, including both Hodgkin and non-Hodgkin variants, evaluating response-adapted therapies and novel drug combinations.

Advanced Hodgkin Lymphoma
Follicular Lymphoma
Treatment optimization

Research aims to improve treatment outcomes while minimizing toxicity.

04 Gastrointestinal Oncology

Investigations into colorectal cancer and related conditions, including innovative surgical approaches and treatment strategies for recurrent disease.

Rectal cancer treatments
Esophagogastric cancer
Surgical innovations

Focus on improving surgical outcomes and treatment effectiveness.

05 Brain Metastases Research

Studies examining treatment options for cerebral radiation necrosis and brain metastases, including innovative detection methods and therapeutic approaches.

Radiation necrosis treatment
Metastatic detection
Targeted therapies

Research aims to improve detection and treatment of brain metastases.

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