Clinical trials in Leidschendam – page 20

1 919 clinical trials in Leidschendam, The Netherlands across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Leidschendam at a glance

1 919

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1 919 trials in Leidschendam

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Rectal cancer

Recruiting

Testing a Drug Combination with Fluorouracil, Irinotecan, Oxaliplatin, and Folinic Acid Plus Radiation Therapy for Patients with Advanced Rectal Cancer

Registered drugNo placebo

Testing a Drug Combination with Fluorouracil, Irinotecan, Oxaliplatin, and Folinic Acid Plus Radiation Therapy for Patients with Advanced Rectal Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Fluorouracil
Sponsor:Catharina Ziekenhuis Stichting

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Brain stem glioma+3

Recruiting

Study of ONC206 for children and young adults with newly diagnosed or recurrent diffuse midline glioma and other recurrent brain tumors

InvestigationalNo placebo

Study of ONC206 for children and young adults with newly diagnosed or recurrent diffuse midline glioma and other recurrent brain tumors

InvestigationalNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:ONC206
Sponsor:Prinses Maxima Centrum voor Kinderoncologie B.V.

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Non-small cell lung cancer

Recruiting

A Study of Telisotuzumab Adizutecan Compared to Standard Treatment in Adults with Advanced Non-Small Cell Lung Cancer After Previous Treatment

Registered drugNo placebo

A Study of Telisotuzumab Adizutecan Compared to Standard Treatment in Adults with Advanced Non-Small Cell Lung Cancer After Previous Treatment

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Amivantamab
Sponsor:AbbVie Deutschland GmbH & Co. KG

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Arteriosclerosis

Recruiting

A Study of Olpasiran for Patients With Stable Heart and Blood Vessel Disease and High Lipoprotein(a) to Measure Changes in Artery Plaque Using Heart Scans

Investigational

A Study of Olpasiran for Patients With Stable Heart and Blood Vessel Disease and High Lipoprotein(a) to Measure Changes in Artery Plaque Using Heart Scans

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:Olpasiran
Sponsor:Amgen Inc.

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Juvenile idiopathic arthritis

Recruiting

Study of abatacept, tocilizumab, and tofacitinib compared to a second TNF inhibitor for children with juvenile idiopathic arthritis who did not respond to TNF inhibitor treatment

Registered drugNo placebo

Study of abatacept, tocilizumab, and tofacitinib compared to a second TNF inhibitor for children with juvenile idiopathic arthritis who did not respond to TNF inhibitor treatment

Registered drugNo placebo

The Netherlands

Participants:0–17 years
Substances:Abatacept
Sponsor:Duke Clinical Research Institute

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Chronic inflammatory demyelinating polyradiculoneuropathy

Recruiting

A study to test if empasiprubart can improve function and is safe for adults with chronic inflammatory demyelinating polyneuropathy

Investigational

A study to test if empasiprubart can improve function and is safe for adults with chronic inflammatory demyelinating polyneuropathy

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:Argenx

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Porphyria non-acute

Recruiting

Long-term study of bitopertin safety and effectiveness in patients with erythropoietic protoporphyria or X-linked protoporphyria

InvestigationalNo placebo

Long-term study of bitopertin safety and effectiveness in patients with erythropoietic protoporphyria or X-linked protoporphyria

InvestigationalNo placebo

The Netherlands

Participants:0–17 years · 18–64 years · 65+ years
Substances:Bitopertin
Sponsor:Disc Medicine Inc.

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Diabetes mellitus+1

Recruiting

A study of estradiol and progesterone treatment for blood sugar control in women with type 1 or type 2 diabetes during or after menopause

Registered drugNo placebo

A study of estradiol and progesterone treatment for blood sugar control in women with type 1 or type 2 diabetes during or after menopause

Registered drugNo placebo

The Netherlands

Participants:18–64 years
Substances:Estradiol
Sponsor:Amsterdam UMC Stichting

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Dilated cardiomyopathy

Recruiting

A Study of Danicamtiv for Adults with Symptomatic Genetic and Familial Dilated Cardiomyopathy to Test if it Improves Heart Function and Exercise Ability

Investigational

A Study of Danicamtiv for Adults with Symptomatic Genetic and Familial Dilated Cardiomyopathy to Test if it Improves Heart Function and Exercise Ability

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:Danicamtiv
Sponsor:Kardigan Inc.

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Squamous cell carcinoma of head and neck

Recruiting

Study of nivolumab and ipilimumab immunotherapy for organ preservation in patients with advanced head and neck squamous cell carcinoma

Registered drugNo placebo

Study of nivolumab and ipilimumab immunotherapy for organ preservation in patients with advanced head and neck squamous cell carcinoma

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Ipilimumab
Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

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Glomerulonephritis membranous

Recruiting

A Study of Povetacicept Compared to Tacrolimus for Adults with Primary Membranous Nephropathy

Registered drug

A Study of Povetacicept Compared to Tacrolimus for Adults with Primary Membranous Nephropathy

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Povetacicept
Sponsor:Vertex Pharmaceuticals Inc.

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Non-small cell lung cancer

Recruiting

Testing zongertinib compared to standard treatment in patients with early-stage non-small cell lung cancer with HER2 mutations after surgery

Registered drugNo placebo

Testing zongertinib compared to standard treatment in patients with early-stage non-small cell lung cancer with HER2 mutations after surgery

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Atezolizumab
Sponsor:Boehringer Ingelheim Espana S.A.

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Clinical research in Leidschendam

What the registry says about research in the country

01 Oncology - Lung Cancer Research

Multiple clinical trials focusing on non-small cell lung cancer (NSCLC) treatment advancements, evaluating novel therapeutic approaches including immunotherapy combinations and targeted treatments.

Advanced NSCLC treatments
Immunotherapy combinations
KRAS G12C inhibitors

Studies compare various treatment options to improve patient outcomes and survival rates.

02 Breast Cancer Studies

Comprehensive research into breast cancer treatments, particularly focusing on hormone receptor-positive and HER2-positive subtypes, investigating targeted therapies and chemotherapy combinations.

Metastatic breast cancer
HER2-positive therapy
Triple-negative breast cancer

Trials examine innovative treatment strategies and personalized approaches.

03 Hematologic Malignancies

Studies focusing on lymphoma treatments, including both Hodgkin and non-Hodgkin variants, evaluating response-adapted therapies and novel drug combinations.

Advanced Hodgkin Lymphoma
Follicular Lymphoma
Treatment optimization

Research aims to improve treatment outcomes while minimizing toxicity.

04 Gastrointestinal Oncology

Investigations into colorectal cancer and related conditions, including innovative surgical approaches and treatment strategies for recurrent disease.

Rectal cancer treatments
Esophagogastric cancer
Surgical innovations

Focus on improving surgical outcomes and treatment effectiveness.

05 Brain Metastases Research

Studies examining treatment options for cerebral radiation necrosis and brain metastases, including innovative detection methods and therapeutic approaches.

Radiation necrosis treatment
Metastatic detection
Targeted therapies

Research aims to improve detection and treatment of brain metastases.

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