Clinical trials in Leidschendam – page 17

1 919 clinical trials in Leidschendam, The Netherlands across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Leidschendam at a glance

1 919

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1 919 trials in Leidschendam

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Drug use disorder

Recruiting

A study to evaluate the effects of CSX-1004 on breathing difficulties caused by fentanyl in healthy adults and people with opioid use disorder

Registered drug

A study to evaluate the effects of CSX-1004 on breathing difficulties caused by fentanyl in healthy adults and people with opioid use disorder

Registered drug

The Netherlands

Participants:18–64 years · Healthy volunteers
Substances:CSX-1004
Sponsor:Cessation Therapeutics Inc.

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Bronchiectasis

Recruiting

A study to evaluate the safety and effectiveness of AZD0292 in people aged 12 years and older with bronchiectasis and chronic Pseudomonas aeruginosa infection

Investigational

A study to evaluate the safety and effectiveness of AZD0292 in people aged 12 years and older with bronchiectasis and chronic Pseudomonas aeruginosa infection

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:AZD0292
Sponsor:AstraZeneca AB

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Gastric cancer

Recruiting

A study of irinotecan and a drug combination for patients with gastric cancer or gastroesophageal junction cancer undergoing surgery.

Registered drugNo placebo

A study of irinotecan and a drug combination for patients with gastric cancer or gastroesophageal junction cancer undergoing surgery.

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Irinotecan Hydrochloride Trihydrate
Sponsor:Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

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Duchenne muscular dystrophy

Recruiting

A study to evaluate the long-term safety and effectiveness of BMN 351 in patients with Duchenne muscular dystrophy amenable to exon 51 skipping.

InvestigationalNo placebo

A study to evaluate the long-term safety and effectiveness of BMN 351 in patients with Duchenne muscular dystrophy amenable to exon 51 skipping.

InvestigationalNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:BMN 351
Sponsor:Biomarin Pharmaceutical Inc.

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Brain neoplasm malignant

Recruiting

Study of the use of tasadenoturev for children and young adults with recurrent or resistant high-grade brain tumors

InvestigationalNo placebo

Study of the use of tasadenoturev for children and young adults with recurrent or resistant high-grade brain tumors

InvestigationalNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Tasadenoturev
Sponsor:Clinica Universidad De Navarra

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Colorectal cancer metastatic

Recruiting

A study of pumitamig and a drug combination versus bevacizumab and a drug combination for patients with untreated, unresectable, or metastatic colorectal cancer

Registered drugNo placebo

A study of pumitamig and a drug combination versus bevacizumab and a drug combination for patients with untreated, unresectable, or metastatic colorectal cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Bevacizumab
Sponsor:Bristol-Myers Squibb Services Unlimited Company

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Systemic scleroderma+5

Recruiting

Using 68Ga-FAPI-46 imaging to detect fibrosis in patients with inflammatory diseases such as Crohn's disease, ulcerative colitis, systemic sclerosis, and lung fibrosis.

InvestigationalNo placebo

Using 68Ga-FAPI-46 imaging to detect fibrosis in patients with inflammatory diseases such as Crohn's disease, ulcerative colitis, systemic sclerosis, and lung fibrosis.

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:Amsterdam UMC Stichting

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Interstitial lung disease+1

Recruiting

A study to evaluate the effectiveness of BI 1015550 in people with lung abnormalities and a family history of pulmonary fibrosis

Investigational

A study to evaluate the effectiveness of BI 1015550 in people with lung abnormalities and a family history of pulmonary fibrosis

Investigational

The Netherlands

Participants:18–64 years · 65+ years · Healthy volunteers
Substances:Nerandomilast
Sponsor:Boehringer Ingelheim International GmbH

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Acute myocardial infarction

Recruiting

A study of tirofiban and adenosine to treat small blood vessel damage in patients with ST-elevation myocardial infarction

Registered drugNo placebo

A study of tirofiban and adenosine to treat small blood vessel damage in patients with ST-elevation myocardial infarction

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Adenosine
Sponsor:Corflow Therapeutics AG

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Peripheral arterial occlusive disease

Recruiting

A study to evaluate the efficacy and safety of orforglipron in patients with peripheral artery disease

Investigational

A study to evaluate the efficacy and safety of orforglipron in patients with peripheral artery disease

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:Orforglipron hemicalcium
Sponsor:Eli Lilly & Co.

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Chronic kidney disease+1

Recruiting

A study to evaluate the effect of orforglipron on cardiovascular health in adults with atherosclerotic cardiovascular disease and/or chronic kidney disease

Investigational

A study to evaluate the effect of orforglipron on cardiovascular health in adults with atherosclerotic cardiovascular disease and/or chronic kidney disease

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:Orforglipron hemicalcium
Sponsor:Eli Lilly & Co.

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Breast cancer metastatic

Recruiting

A study of palazestrant and ribociclib compared to letrozole and ribociclib for patients with advanced ER+ HER2- breast cancer

Registered drug

A study of palazestrant and ribociclib compared to letrozole and ribociclib for patients with advanced ER+ HER2- breast cancer

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Letrozole
Sponsor:Olema Pharmaceuticals Inc.

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Clinical research in Leidschendam

What the registry says about research in the country

01 Oncology - Lung Cancer Research

Multiple clinical trials focusing on non-small cell lung cancer (NSCLC) treatment advancements, evaluating novel therapeutic approaches including immunotherapy combinations and targeted treatments.

Advanced NSCLC treatments
Immunotherapy combinations
KRAS G12C inhibitors

Studies compare various treatment options to improve patient outcomes and survival rates.

02 Breast Cancer Studies

Comprehensive research into breast cancer treatments, particularly focusing on hormone receptor-positive and HER2-positive subtypes, investigating targeted therapies and chemotherapy combinations.

Metastatic breast cancer
HER2-positive therapy
Triple-negative breast cancer

Trials examine innovative treatment strategies and personalized approaches.

03 Hematologic Malignancies

Studies focusing on lymphoma treatments, including both Hodgkin and non-Hodgkin variants, evaluating response-adapted therapies and novel drug combinations.

Advanced Hodgkin Lymphoma
Follicular Lymphoma
Treatment optimization

Research aims to improve treatment outcomes while minimizing toxicity.

04 Gastrointestinal Oncology

Investigations into colorectal cancer and related conditions, including innovative surgical approaches and treatment strategies for recurrent disease.

Rectal cancer treatments
Esophagogastric cancer
Surgical innovations

Focus on improving surgical outcomes and treatment effectiveness.

05 Brain Metastases Research

Studies examining treatment options for cerebral radiation necrosis and brain metastases, including innovative detection methods and therapeutic approaches.

Radiation necrosis treatment
Metastatic detection
Targeted therapies

Research aims to improve detection and treatment of brain metastases.

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