Clinical trials in Leiden – page 80

1 938 clinical trials in Leiden, The Netherlands across 4 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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1 938

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1 938 trials in Leiden

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Drug dependence

Not yet recruiting

Study on Sustained-Release Dexamphetamine and Piracetam for Patients with Moderate to Severe Cocaine Use Disorder and Opioid Dependence

Investigational

Study on Sustained-Release Dexamphetamine and Piracetam for Patients with Moderate to Severe Cocaine Use Disorder and Opioid Dependence

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:Piracetam
Sponsor:Parnassia Groep B.V.

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Anal fistula+2

Not yet recruiting

Study on Antibiotic Treatment with Metronidazole and Ciprofloxacin for Patients with Perianal Abscess After Surgery

Registered drug

Study on Antibiotic Treatment with Metronidazole and Ciprofloxacin for Patients with Perianal Abscess After Surgery

Registered drug

The Netherlands

Participants:18–64 years · 65+ years
Substances:Ciprofloxacin
Sponsor:Amsterdam UMC Stichting

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Catatonia+1

Not yet recruiting

Study on Sodium Oxybate for Treating Catatonia in Patients with Depression, Bipolar Disorder, or Psychotic Disorder

Registered drugNo placebo

Study on Sodium Oxybate for Treating Catatonia in Patients with Depression, Bipolar Disorder, or Psychotic Disorder

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Sodium Oxybate
Sponsor:Amsterdam UMC Stichting

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Depression

Not yet recruiting

Title: Comparison of Oral Esketamine versus Electroconvulsive Therapy in Patients with Treatment-Resistant Depression

Registered drugNo placebo

Title: Comparison of Oral Esketamine versus Electroconvulsive Therapy in Patients with Treatment-Resistant Depression

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Esketamine
Sponsor:Universitair Medisch Centrum Groningen

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Pulmonary fibrosis

Not yet recruiting

Study on PET/CT Imaging with [18F]-AlF-FAPI-74 for Identifying Fibrosis and Inflammation in Patients with Progressive Pulmonary Fibrosis

InvestigationalNo placebo

Study on PET/CT Imaging with [18F]-AlF-FAPI-74 for Identifying Fibrosis and Inflammation in Patients with Progressive Pulmonary Fibrosis

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:St. Antonius Ziekenhuis

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Non-small cell lung cancer

Not yet recruiting

Study to Compare Zongertinib with Standard Treatment for Patients with Advanced Non-Small Cell Lung Cancer with HER2 Mutations

Registered drugNo placebo

Study to Compare Zongertinib with Standard Treatment for Patients with Advanced Non-Small Cell Lung Cancer with HER2 Mutations

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Carboplatin
Sponsor:Boehringer Ingelheim Espana S.A.

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Metastases to peritoneum

Not yet recruiting

Study of Radspherin® for Patients with Peritoneal Cancer from Colorectal Cancer After Surgery and Chemotherapy

InvestigationalNo placebo

Study of Radspherin® for Patients with Peritoneal Cancer from Colorectal Cancer After Surgery and Chemotherapy

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:Oncoinvent ASA

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Brain stem glioma+1

Not yet recruiting

Study on ONC201 and Paxalisib for Children and Young Adults with Diffuse Midline Gliomas, Including Diffuse Intrinsic Pontine Gliomas

InvestigationalNo placebo

Study on ONC201 and Paxalisib for Children and Young Adults with Diffuse Midline Gliomas, Including Diffuse Intrinsic Pontine Gliomas

InvestigationalNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Dordaviprone
Sponsor:Prinses Maxima Centrum voor Kinderoncologie B.V.

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Procedural pain

Not yet recruiting

Study on Pain Relief After Breast Cancer Surgery: Comparing Liposomal Bupivacaine and Levobupivacaine in Patients Undergoing Mastectomy

Registered drugNo placebo

Study on Pain Relief After Breast Cancer Surgery: Comparing Liposomal Bupivacaine and Levobupivacaine in Patients Undergoing Mastectomy

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Bupivacaine
Sponsor:St. Antonius Ziekenhuis

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Colorectal cancer metastatic

Not yet recruiting

Study of LB-100 and Azenosertib for Patients with Metastatic Colorectal Cancer

InvestigationalNo placebo

Study of LB-100 and Azenosertib for Patients with Metastatic Colorectal Cancer

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Azenosertib
Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

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Renal cell carcinoma

Not yet recruiting

Study of Axitinib and Avelumab for Patients with Localized Renal Cell Carcinoma at Moderate to High Risk of Recurrence

Registered drugNo placebo

Study of Axitinib and Avelumab for Patients with Localized Renal Cell Carcinoma at Moderate to High Risk of Recurrence

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Avelumab
Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

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Skin squamous cell carcinoma metastatic+1

Not yet recruiting

Study of INCB099280 for Patients With Advanced Cutaneous Squamous Cell Carcinoma Not Suitable for Surgery or Radiotherapy

InvestigationalNo placebo

Study of INCB099280 for Patients With Advanced Cutaneous Squamous Cell Carcinoma Not Suitable for Surgery or Radiotherapy

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:INCB099280
Sponsor:Incyte Corp.

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Clinical research in Leiden

What the registry says about research in the country

01 Infectious Diseases Research

Innovative studies focusing on viral infections including trials evaluating vaccines against yellow fever, influenza, and mpox. Research includes assessment of antibody responses and vaccine effectiveness in different populations.

Influenza vaccine efficacy in elderly
Yellow fever prophylaxis
Mpox booster vaccination

Particular emphasis on preventive strategies and immune response evaluation.

02 Neurological Studies

Comprehensive research targeting neurological conditions, including investigations into Parkinson's disease treatments and neural response patterns. Studies examine innovative therapeutic approaches.

Parkinson's Disease treatments
CNS response analysis
Cerebral Amyloid Angiopathy

Focus on developing targeted therapies and understanding brain mechanisms.

03 Cancer and Chronic Conditions

Advanced research in oncology and chronic diseases, including studies on gastric cancer imaging and T-cell lymphoma treatments. Investigations into kidney disease management.

Advanced solid tumors
Gastric cancer diagnosis
Chronic kidney disease

Emphasis on innovative diagnostic techniques and treatment approaches.

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