Clinical trials in Leiden – page 43

1 938 clinical trials in Leiden, The Netherlands across 4 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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1 938

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1 938 trials in Leiden

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Non-small cell lung cancer metastatic

Recruiting

Study on the Safety and Effects of STX-241 for Patients with Advanced Non-Small Cell Lung Cancer Resistant to EGFR Inhibitors

InvestigationalNo placebo

Study on the Safety and Effects of STX-241 for Patients with Advanced Non-Small Cell Lung Cancer Resistant to EGFR Inhibitors

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:STX-241
Sponsor:Pierre Fabre Medicament

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Sedative therapy+1

Recruiting

A Study Comparing Remimazolam and Midazolam for Sedation in Adults During Upper Gastrointestinal Endoscopy

Registered drugNo placebo

A Study Comparing Remimazolam and Midazolam for Sedation in Adults During Upper Gastrointestinal Endoscopy

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Midazolam
Sponsor:Sint Antonius Ziekenhuis Stichting

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Duchenne muscular dystrophy

Recruiting

Long-Term Safety and Efficacy Study of Givinostat for Patients with Duchenne Muscular Dystrophy Previously Treated with Givinostat

InvestigationalNo placebo

Long-Term Safety and Efficacy Study of Givinostat for Patients with Duchenne Muscular Dystrophy Previously Treated with Givinostat

InvestigationalNo placebo

The Netherlands

Participants:0–17 years · 18–64 years
Substances:Givinostat
Sponsor:Italfarmaco S.p.A.

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HER2 gene amplification

Recruiting

Study of zongertinib tablets in patients with advanced solid tumors that have HER2 gene changes

InvestigationalNo placebo

Study of zongertinib tablets in patients with advanced solid tumors that have HER2 gene changes

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Zongertinib
Sponsor:Boehringer Ingelheim Espana S.A.

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Non-small cell lung cancer+4

Recruiting

Study on the Effects of Adding Durvalumab After Chemotherapy and Surgery in Patients with Resectable Non-Small Cell Lung Cancer

Registered drugNo placebo

Study on the Effects of Adding Durvalumab After Chemotherapy and Surgery in Patients with Resectable Non-Small Cell Lung Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Carboplatin
Sponsor:ETOP IBCSG Partners Foundation

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Giant cell arteritis

Recruiting

Study on [18F]Fluoro-PEG-Folate Imaging for Patients with Giant Cell Arteritis

InvestigationalNo placebo

Study on [18F]Fluoro-PEG-Folate Imaging for Patients with Giant Cell Arteritis

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Sponsor:Universitair Medisch Centrum Groningen

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Paroxysmal nocturnal haemoglobinuria

Recruiting

Study of pegcetacoplan safety and effectiveness in adolescents aged 12-17 with paroxysmal nocturnal hemoglobinuria

Registered drugNo placebo

Study of pegcetacoplan safety and effectiveness in adolescents aged 12-17 with paroxysmal nocturnal hemoglobinuria

Registered drugNo placebo

The Netherlands

Participants:0–17 years
Substances:Pegcetacoplan
Sponsor:Apellis Pharmaceuticals Inc.

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Progressive multiple sclerosis

Recruiting

Study on the Effects of Vidofludimus Calcium (IMU-838) in Patients with Progressive Multiple Sclerosis

Investigational

Study on the Effects of Vidofludimus Calcium (IMU-838) in Patients with Progressive Multiple Sclerosis

Investigational

The Netherlands

Participants:18–64 years
Substances:Vidofludimus Calcium
Sponsor:Immunic AG

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Uveal melanoma

Recruiting

Study of ipilimumab, nivolumab and melphalan combination therapy with hepatic perfusion in patients with advanced uveal melanoma that has spread to other organs

Registered drugNo placebo

Study of ipilimumab, nivolumab and melphalan combination therapy with hepatic perfusion in patients with advanced uveal melanoma that has spread to other organs

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Ipilimumab
Sponsor:Leids Universitair Medisch Centrum (LUMC)

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Chronic myeloid leukaemia

Recruiting

Study on Stopping Dasatinib in Patients with Chronic Myeloid Leukemia After a Previous Attempt to Stop Treatment

Registered drugNo placebo

Study on Stopping Dasatinib in Patients with Chronic Myeloid Leukemia After a Previous Attempt to Stop Treatment

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Dasatinib
Sponsor:Region Uppsala

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Uveal melanoma

Recruiting

Title: Comparing tebentafusp treatment versus observation in patients with high-risk eye melanoma (uveal melanoma) after initial treatment

Registered drugNo placebo

Title: Comparing tebentafusp treatment versus observation in patients with high-risk eye melanoma (uveal melanoma) after initial treatment

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Tebentafusp
Sponsor:European Organisation For Research And Treatment Of Cancer

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Non-small cell lung cancer+1

Recruiting

Study of Durvalumab, Tremelimumab, Chemotherapy, and Radiotherapy for Patients with Newly Diagnosed Non-Small Cell Lung Cancer with Limited Spread

Registered drugNo placebo

Study of Durvalumab, Tremelimumab, Chemotherapy, and Radiotherapy for Patients with Newly Diagnosed Non-Small Cell Lung Cancer with Limited Spread

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Durvalumab
Sponsor:ETOP IBCSG Partners Foundation

Contact Research Centre

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Clinical research in Leiden

What the registry says about research in the country

01 Infectious Diseases Research

Innovative studies focusing on viral infections including trials evaluating vaccines against yellow fever, influenza, and mpox. Research includes assessment of antibody responses and vaccine effectiveness in different populations.

Influenza vaccine efficacy in elderly
Yellow fever prophylaxis
Mpox booster vaccination

Particular emphasis on preventive strategies and immune response evaluation.

02 Neurological Studies

Comprehensive research targeting neurological conditions, including investigations into Parkinson's disease treatments and neural response patterns. Studies examine innovative therapeutic approaches.

Parkinson's Disease treatments
CNS response analysis
Cerebral Amyloid Angiopathy

Focus on developing targeted therapies and understanding brain mechanisms.

03 Cancer and Chronic Conditions

Advanced research in oncology and chronic diseases, including studies on gastric cancer imaging and T-cell lymphoma treatments. Investigations into kidney disease management.

Advanced solid tumors
Gastric cancer diagnosis
Chronic kidney disease

Emphasis on innovative diagnostic techniques and treatment approaches.

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