Clinical trials in Leiden – page 13

406 clinical trials in Leiden, The Netherlands across 4 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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406 trials in Leiden

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Infection prophylaxis

Recruiting

Study of cefuroxime and metronidazole to prevent infections after Whipple's procedure in patients with high risk of bile contamination

Registered drugNo placebo

Study of cefuroxime and metronidazole to prevent infections after Whipple's procedure in patients with high risk of bile contamination

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Cefuroxime
Sponsor:Leiden University Medical Center

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Non-small cell lung cancer

Recruiting

Study of RMC-6291 and Pembrolizumab with or without Chemotherapy for Patients with Advanced KRAS G12C Mutated Lung Cancer

Registered drugNo placebo

Study of RMC-6291 and Pembrolizumab with or without Chemotherapy for Patients with Advanced KRAS G12C Mutated Lung Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Carboplatin
Sponsor:Revolution Medicines Inc.

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Myasthenia gravis

Recruiting

Study on the Safety and Effectiveness of NMD670 for Adults with Myasthenia Gravis

Investigational

Study on the Safety and Effectiveness of NMD670 for Adults with Myasthenia Gravis

Investigational

The Netherlands

Participants:18–64 years · 65+ years
Substances:NMD670
Sponsor:NMD Pharma A/S

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Chronic lymphocytic leukaemia+1

Recruiting

Long-Term Safety Study of BCMACP03, BCN-CP01, and 19CP02 for Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma, CLL, SLL, or Multiple Myeloma

InvestigationalNo placebo

Long-Term Safety Study of BCMACP03, BCN-CP01, and 19CP02 for Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma, CLL, SLL, or Multiple Myeloma

InvestigationalNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:BCMACP03
Sponsor:Galapagos

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Myasthenia gravis

Recruiting

Study on Efgartigimod for Children Aged 2-17 with Generalized Myasthenia Gravis

Registered drugNo placebo

Study on Efgartigimod for Children Aged 2-17 with Generalized Myasthenia Gravis

Registered drugNo placebo

The Netherlands

Participants:0–17 years
Substances:Efgartigimod Alfa
Sponsor:Argenx

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Non-small cell lung cancer

Recruiting

Study of RMC-6236 and Pembrolizumab with or without Chemotherapy for Patients with RAS-Mutated Non-Small Cell Lung Cancer

Registered drugNo placebo

Study of RMC-6236 and Pembrolizumab with or without Chemotherapy for Patients with RAS-Mutated Non-Small Cell Lung Cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Carboplatin
Sponsor:Revolution Medicines Inc.

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Factor VIII deficiency

Recruiting

Study on Personalized Dosing of Emicizumab for Patients with Congenital Hemophilia A

Registered drugNo placebo

Study on Personalized Dosing of Emicizumab for Patients with Congenital Hemophilia A

Registered drugNo placebo

The Netherlands

Participants:0–17 years · 18–64 years · 65+ years
Substances:Emicizumab
Sponsor:Universitair Medisch Centrum Utrecht

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Cytomegalovirus infection+2

Recruiting

Study on Treating Resistant Viral Infections in Stem Cell Transplant Patients Using Allogeneic Multivirus-Specific T Cells

Investigational

Study on Treating Resistant Viral Infections in Stem Cell Transplant Patients Using Allogeneic Multivirus-Specific T Cells

Investigational

The Netherlands

Participants:0–17 years · 18–64 years · 65+ years
Substances:Allogeneic Cd4+ And Cd8+ T Lymphocytes Ex Vivo Incubated With Synthetic Peptides Of The Viral Antigens Of Cytomegalovirus, Adenovirus And Epstein-Barr Virus
Sponsor:Medical Center - University Of Freiburg

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Colorectal cancer metastatic+2

Recruiting

Study on the Effectiveness of Floxuridine and Drug Combination for Patients with Unresectable Colorectal Liver Metastases

Registered drugNo placebo

Study on the Effectiveness of Floxuridine and Drug Combination for Patients with Unresectable Colorectal Liver Metastases

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Bevacizumab
Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

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Pancreatic carcinoma

Recruiting

Study of personalized FOLFIRINOX drug combination dosing (fluorouracil, irinotecan, oxaliplatin, and calcium folinate) for patients with pancreatic cancer

Registered drugNo placebo

Study of personalized FOLFIRINOX drug combination dosing (fluorouracil, irinotecan, oxaliplatin, and calcium folinate) for patients with pancreatic cancer

Registered drugNo placebo

The Netherlands

Participants:18–64 years · 65+ years
Substances:Calcium Folinate
Sponsor:Catharina Ziekenhuis Stichting

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Cervix carcinoma

Recruiting

Study on Fertility Preservation in Women with Stage IB2 Cervical Cancer Using Cisplatin, Carboplatin, and Paclitaxel Before Surgery

Registered drugNo placebo

Study on Fertility Preservation in Women with Stage IB2 Cervical Cancer Using Cisplatin, Carboplatin, and Paclitaxel Before Surgery

Registered drugNo placebo

The Netherlands

Participants:18–64 years
Substances:Carboplatin
Sponsor:Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting

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Habitual abortion

Recruiting

Study on Prednisolone for Women with Unexplained Recurrent Miscarriages

Registered drug

Study on Prednisolone for Women with Unexplained Recurrent Miscarriages

Registered drug

The Netherlands

Participants:18–64 years
Substances:Prednisolone
Sponsor:Leiden University Medical Center

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Clinical research in Leiden

What the registry says about research in the country

01 Infectious Diseases Research

Innovative studies focusing on viral infections including trials evaluating vaccines against yellow fever, influenza, and mpox. Research includes assessment of antibody responses and vaccine effectiveness in different populations.

Influenza vaccine efficacy in elderly
Yellow fever prophylaxis
Mpox booster vaccination

Particular emphasis on preventive strategies and immune response evaluation.

02 Neurological Studies

Comprehensive research targeting neurological conditions, including investigations into Parkinson's disease treatments and neural response patterns. Studies examine innovative therapeutic approaches.

Parkinson's Disease treatments
CNS response analysis
Cerebral Amyloid Angiopathy

Focus on developing targeted therapies and understanding brain mechanisms.

03 Cancer and Chronic Conditions

Advanced research in oncology and chronic diseases, including studies on gastric cancer imaging and T-cell lymphoma treatments. Investigations into kidney disease management.

Advanced solid tumors
Gastric cancer diagnosis
Chronic kidney disease

Emphasis on innovative diagnostic techniques and treatment approaches.

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