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Clinical trials in Coimbra – page 11

263 clinical trials in Coimbra, Portugal across 2 research sites. Every trial is listed in the EU Clinical Trials Register and updated daily.

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Coimbra at a glance
263
clinical trials
  • Research sites2
Type of trial
Recruitment status
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263 trials in Coimbra

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Myasthenia gravis

Not yet recruiting

Efficacy and Safety of DNTH103 in Adults with Generalized Myasthenia Gravis: A Phase 3 Randomized, Double‑Blind, Placebo‑Controlled Study

Investigational
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:DNTH103
  • Sponsor:Dianthus Therapeutics Inc.

Endometrial cancer

Not yet recruiting

Study of GSK5733584 versus paclitaxel or doxorubicin in patients with advanced or recurrent endometrial cancer after platinum‑based chemotherapy and immunotherapy

Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:GSK5733584
  • Sponsor:Glaxosmithkline Research & Development Limited

Safety and Tolerability of Intrathecal ION337 in Patients with Dravet Syndrome

InvestigationalNo placebo
Countries:PortugalPortugal
  • Participants:0–17 years
  • Sponsor:Ionis Pharmaceuticals Inc.

A study to evaluate the safety and effectiveness of zampilimab in people with idiopathic pulmonary fibrosis

Investigational
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Zampilimab
  • Sponsor:Chiesi Farmaceutici S.p.A.

Type 2 diabetes mellitus

Not yet recruiting

A study to evaluate the effectiveness of NNC0662-0419 and semaglutide in people with type 2 diabetes

Registered drug
Countries:PortugalPortugal
  • Participants:18–64 years · Healthy volunteers
  • Substances:Semaglutide
  • Sponsor:Novo Nordisk A/S

A study to evaluate the safety and effectiveness of ADX-038 in adults with geographic atrophy caused by age-related macular degeneration.

Registered drug
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:ADX-038
  • Sponsor:Adarx Pharmaceuticals Inc.

Pneumonia bacterial

Not yet recruiting

Safety and tolerability study of bacteriophage cocktail TP-122A given by inhalation in adults with ventilator-associated pneumonia

Investigational
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Demerecviridae bacteriophage against klebesiella pneumoniae (113.073 BP)
  • Sponsor:Technophage Investigacao E Desenvolvimento Em Biotecnologia S.A.

Ischaemic stroke

Not yet recruiting

Study on the Effects of CD34+ Cells for Patients with Acute Ischemic Stroke

Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:AUTOLOGOUS CD34+ ENRICHED CELL FRACTION THAT CONTAINS CD34+ CELLS TRANSDUCED WITH RETROVIRAL VECTOR THAT ENCODES FOR THE HUMAN ADA CDNA SEQUENCE
  • Sponsor:Unidade Local De Saude De Coimbra E.P.E.

Macular oedema

Not yet recruiting

Study on the Effects of RO7200220 for Patients with Uveitic Macular Edema

InvestigationalNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Humanised IgG2 monoclonal antibody against INTERLEUKIN-6
  • Sponsor:F. Hoffmann-La Roche AG

Acute myeloid leukaemia

Not yet recruiting

Study on the Safety of Ivosidenib and Azacitidine for Adults with Newly Diagnosed IDH1m Acute Myeloid Leukemia Not Eligible for Intensive Chemotherapy

Registered drugNo placebo
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Azacitidine
  • Sponsor:Servier Affaires Medicales

Oral Semaglutide in People With Mild Cognitive Impairment or Mild Dementia of the Alzheimer’s Type

Registered drug
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Substances:Semaglutide
  • Sponsor:Novo Nordisk A/S

Arteriosclerosis

Not recruiting

A study to evaluate the effect of olpasiran on major cardiovascular events in patients with atherosclerotic cardiovascular disease and high levels of lipoprotein(a)

Investigational
Countries:PortugalPortugal
  • Participants:18–64 years · 65+ years
  • Sponsor:Amgen Inc.

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Clinical research in Coimbra

What the registry says about research in the country

01 Ophthalmology & Vision

Innovative trials investigating treatments for polypoidal choroidal vasculopathy and thyroid eye disease, focusing on improving visual outcomes and reducing eye-related complications.

  • Retinal conditions
  • Orbital disorders
  • Visual acuity improvement

Advanced therapeutic approaches using intravitreal injections and targeted medications.

02 Dermatology

Groundbreaking research addressing various skin conditions including hidradenitis suppurativa, pyoderma gangrenosum, and neurodermatitis.

  • Inflammatory skin diseases
  • Chronic skin conditions
  • Autoimmune dermatological disorders

Novel therapeutic approaches targeting specific inflammatory pathways.

03 Cardiovascular Medicine

Comprehensive studies exploring treatments for cardiovascular disease and pulmonary arterial hypertension, with focus on preventing major adverse cardiac events.

  • Heart disease prevention
  • Vascular conditions
  • Lipid management

Innovative therapies targeting specific cardiovascular risk factors.

04 Neurology

Advanced research in ischemic stroke, epilepsy, and migraine treatments, exploring both acute interventions and preventive therapies.

  • Stroke management
  • Seizure disorders
  • Headache conditions

Cutting-edge therapeutic approaches for neurological disorders.

05 Oncology

Studies focusing on breast cancer, non-small cell lung cancer, and leiomyosarcoma, developing targeted therapies for various cancer types.

  • Metastatic disease
  • Combination therapies
  • Targeted treatments

Innovative approaches in cancer treatment and management.

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