Clinical trials in Ceske Budejovice

65 clinical trials in Ceske Budejovice, Czechia across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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65 trials in Ceske Budejovice

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Obesity+2

Recruiting

Effect of zenagamtide on major adverse cardiovascular events in overweight or obese adults with established atherosclerotic cardiovascular disease

Investigational

Effect of zenagamtide on major adverse cardiovascular events in overweight or obese adults with established atherosclerotic cardiovascular disease

Investigational

Czechia

Participants:18–64 years
Substances:POLYPEPTIDE CONSISTING OF A GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST AND AN AMYLIN RECEPTOR AGONIST, CONNECTED BY A LINKER WITH 4 GLYCINE RESIDUES, AND CONNECTED TO A C18 FATTY ACID SIDE CHAIN
Sponsor:Novo Nordisk A/S

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Type 2 diabetes mellitus

Recruiting

A Phase III Randomized Double‑Blind Study of Elecoglipron for Adults with Type 2 Diabetes on Insulin

Investigational

A Phase III Randomized Double‑Blind Study of Elecoglipron for Adults with Type 2 Diabetes on Insulin

Investigational

Czechia

Participants:18–64 years · 65+ years
Substances:AZD5004
Sponsor:AstraZeneca AB

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Contraception+1

Recruiting

Contraceptive efficacy, safety and tolerability of drospirenone 4 mg (LPRI‑CF113) in healthy women of reproductive age over 13 cycles

InvestigationalNo placebo

Contraceptive efficacy, safety and tolerability of drospirenone 4 mg (LPRI‑CF113) in healthy women of reproductive age over 13 cycles

InvestigationalNo placebo

Czechia

Participants:0–17 years · 18–64 years · Healthy volunteers
Substances:Drospirenone
Sponsor:Chemo Research S.L.

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Arteriosclerosis

Recruiting

Study of laroprovstat (AZD0780) to reduce heart attack, stroke and vascular complications in patients with atherosclerotic cardiovascular disease or high risk of developing it

Investigational

Study of laroprovstat (AZD0780) to reduce heart attack, stroke and vascular complications in patients with atherosclerotic cardiovascular disease or high risk of developing it

Investigational

Czechia

Participants:18–64 years · 65+ years
Substances:Laroprovstat
Sponsor:AstraZeneca AB

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Crohn's disease

Recruiting

Testing SAR442970 compared to placebo in adults with moderate to severe Crohn's disease

Investigational

Testing SAR442970 compared to placebo in adults with moderate to severe Crohn's disease

Investigational

Czechia

Participants:18–64 years · 65+ years
Substances:SAR442970
Sponsor:Sanofi-Aventis Recherche & Developpement

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Colitis ulcerative+1

Recruiting

Study on Long-term Safety of Zasocitinib for Adults with Moderate to Severe Ulcerative Colitis and Crohn's Disease

InvestigationalNo placebo

Study on Long-term Safety of Zasocitinib for Adults with Moderate to Severe Ulcerative Colitis and Crohn's Disease

InvestigationalNo placebo

Czechia

Participants:18–64 years · 65+ years
Substances:Zasocitinib
Sponsor:Takeda Development Center Americas Inc.

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Crohn's disease

Recruiting

Study of RO7790121 (afimkibart) for Treatment and Long-term Management in Adults with Moderate to Severe Crohn's Disease

Investigational

Study of RO7790121 (afimkibart) for Treatment and Long-term Management in Adults with Moderate to Severe Crohn's Disease

Investigational

Czechia

Participants:18–64 years · 65+ years
Substances:RO7790121
Sponsor:F. Hoffmann-La Roche AG

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Acute myocardial infarction

Recruiting

Study on Selatogrel for Preventing Heart Attack in Patients with Recent Heart Attack History

Investigational

Study on Selatogrel for Preventing Heart Attack in Patients with Recent Heart Attack History

Investigational

Czechia

Participants:18–64 years · 65+ years
Substances:Selatogrel
Sponsor:Viatris Innovation GmbH

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Conjunctivitis allergic

Recruiting

Study on the Effectiveness of PQ Grass for Children and Teens with Seasonal Allergies from Grass Pollen

Registered drug

Study on the Effectiveness of PQ Grass for Children and Teens with Seasonal Allergies from Grass Pollen

Registered drug

Czechia

Participants:0–17 years
Substances:Desloratadine
Sponsor:Allergy Therapeutics (UK) Limited

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Crohn's disease

Recruiting

Study on the Effects of Zasocitinib for Patients with Moderate to Severe Crohn's Disease

Investigational

Study on the Effects of Zasocitinib for Patients with Moderate to Severe Crohn's Disease

Investigational

Czechia

Participants:18–64 years · 65+ years
Substances:Zasocitinib
Sponsor:Takeda Development Center Americas Inc.

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Colitis ulcerative

Recruiting

Efficacy and Safety of JNJ-78934804 (guselkumab and golimumab) in Adults with Moderately to Severely Active Ulcerative Colitis

InvestigationalNo placebo

Efficacy and Safety of JNJ-78934804 (guselkumab and golimumab) in Adults with Moderately to Severely Active Ulcerative Colitis

InvestigationalNo placebo

Czechia

Participants:18–64 years · 65+ years
Substances:Golimumab
Sponsor:Janssen Cilag International

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Dyslipidaemia

Recruiting

Comparison of Obicetrapib and Bempedoic Acid in Patients with Dyslipidemia at High to Very High Cardiovascular Risk

Registered drug

Comparison of Obicetrapib and Bempedoic Acid in Patients with Dyslipidemia at High to Very High Cardiovascular Risk

Registered drug

Czechia

Participants:18–64 years · 65+ years
Substances:Bempedoic Acid

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Clinical research in Ceske Budejovice

What the registry says about research in the country

01 Infectious Diseases Research

Current trials focus on evaluating novel treatments for respiratory syncytial virus (RSV) and Clostridioides difficile infections. Studies are investigating the effectiveness of vaccines against meningococcal infections in infants and examining immune responses to influenza vaccines in older adults.

Meningococcal prevention
Influenza vaccination
RSV treatment

Particular attention is being paid to vaccine development and optimization of treatment durations.

02 Gastrointestinal Disorders

Extensive research is underway in treating inflammatory bowel diseases, with multiple trials examining new therapies for both Crohn's Disease and Ulcerative Colitis. Studies are evaluating various biological treatments and their effectiveness in managing moderate to severe cases.

Crohn's Disease therapies
Ulcerative Colitis treatments
Inflammatory response management

These trials aim to improve treatment outcomes and quality of life for patients with chronic gastrointestinal conditions.

03 Cardiovascular Health

Studies are investigating new approaches to prevent stroke and manage cardiovascular complications in patients with atrial fibrillation. Research includes evaluation of novel medications for acute myocardial infarction and stroke prevention strategies.

Stroke prevention
Heart attack management
Blood clot prevention

Focus is on developing rapid-response treatments and preventive therapies for high-risk patients.

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