Groundbreaking trials focusing on head and neck squamous cell carcinoma, exploring innovative treatments combining radiotherapy with targeted therapies. Studies also examine new approaches for esophageal cancer and pancreatic adenocarcinoma.

Advanced Cancer Therapies
Combination Treatments
Targeted Therapeutics

Multiple trials are investigating novel drug combinations and immunotherapy approaches for various cancer types.

02 Autoimmune Conditions

Comprehensive research into Sjögren's syndrome treatment options, including innovative biological therapies and histopathological studies. Additional focus on rheumatoid arthritis and novel therapeutic approaches.

Biological Treatments
Disease Mechanisms
Treatment Response

Studies aim to understand disease mechanisms and evaluate new therapeutic options for autoimmune disorders.

03 Cardiovascular and Respiratory Studies

Investigation of treatments for pulmonary arterial hypertension and heart failure prevention. Research includes innovative drug combinations and preventive approaches for cardiovascular conditions.

Heart Failure Prevention
Hypertension Management
Asthma Control

Focus on developing effective treatments for chronic cardiovascular and respiratory conditions.

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Clinical trials in Brest – page 26

584 trials in Brest

B-cell lymphoma+1

Comparing human normal immunoglobulin (iv) and a drug combination to prevent infections in adults with B-cell acute lymphoblastic leukemia or B-cell lymphoma treated with CAR-T cells

Non-small cell lung cancer

A study to evaluate the safety and effectiveness of petosemtamab and pembrolizumab in adults with non-small cell lung cancer

Plasma cell myeloma

A study of belantamab mafodotin and mezigdomide in patients with relapsed multiple myeloma who have previously received CAR-T cell therapy or bispecific antibodies

Ischaemic stroke

Comparing tenecteplase and mechanical clot removal versus mechanical clot removal alone for adults with a large ischemic stroke

Malformation venous+1

Study of acetylsalicylic acid and diclofenac for treating blood clots in superficial venous malformations in children aged 6 to 17 years

Mechanical ventilation+1

Study of dexmedetomidine versus placebo to reduce opioid use in premature babies requiring mechanical ventilation for respiratory distress

Pulmonary fibrosis

A study to evaluate the effectiveness and safety of admilparant in patients with progressive pulmonary fibrosis

Idiopathic pulmonary fibrosis

A study to evaluate the effectiveness and safety of admilparant in patients with idiopathic pulmonary fibrosis

Chemical burn

Treatment of Severe Eye Chemical Burns with Allogeneic Bone Marrow-Derived Mesenchymal Stromal Cells for Patients with Severe Ocular Chemical Burns

Testing inotuzumab ozogamicin and blinatumomab with drug combination for children with relapsed precursor B-cell acute lymphoblastic leukemia

Testing inotuzumab ozogamicin and blinatumomab with drug combination for children with relapsed precursor B-cell acute lymphoblastic leukemia

Congenital megacolon

Study of sodium butyrate enemas for bowel function recovery after surgery in children and adults with Hirschsprung's disease

Rectal adenocarcinoma

Study of drug combination with radiotherapy versus radiotherapy alone for locally advanced rectal cancer in patients 75 years and older

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