Clinical trials in Bremen – page 8

118 clinical trials in Bremen, Germany across 1 research site. Every trial is listed in the EU Clinical Trials Register and updated daily.

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118

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118 trials in Bremen

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Study of Copanlisib with Rituximab and CHOP for Untreated Diffuse Large B-Cell Lymphoma in Patients Aged 18-80

Registered drugNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:Cyclophosphamide
Sponsor:Universitaetsklinikum Muenster AöR

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Study on Fianlimab and Cemiplimab for Adults with Resectable Stage III and IV Melanoma

Registered drug

Germany

Participants:18–64 years · 65+ years
Substances:Cemiplimab
Sponsor:Regeneron Pharmaceuticals Inc.

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Study Comparing Ribociclib and Endocrine Therapy to Chemotherapy for Patients with Intermediate-Risk HR+/HER2- Early Breast Cancer

Registered drugNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:Ribociclib
Sponsor:WSG Women's Cancer Study Group GmbH

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Study on Reducing Side Effects in Advanced Hodgkin Lymphoma Using Brentuximab Vedotin and Drug Combination for Newly Diagnosed Patients

Not recruiting

Registered drugNo placebo

Study on Reducing Side Effects in Advanced Hodgkin Lymphoma Using Brentuximab Vedotin and Drug Combination for Newly Diagnosed Patients

Registered drugNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:Bleomycin Sulfate
Sponsor:University Of Cologne

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Study Comparing FOLFOX Before Surgery to Risk-Adapted Chemotherapy After Surgery for Patients with Locally Advanced Rectal Cancer and Low Risk of Local Failure

Registered drugNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:Capecitabine
Sponsor:Heidelberg University

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Study on Molidustat and Ivosidenib for Adults with Relapsed or Refractory IDH1-Mutated Acute Myeloid Leukemia or Myelodysplastic Syndrome

Registered drugNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:Ivosidenib
Sponsor:Medizinische Hochschule Hannover

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Central nervous system lymphoma

Not recruiting

Registered drugNo placebo

Study on De-escalated Induction Therapy with Methotrexate, Cytarabine, Thiotepa, and Rituximab for Newly Diagnosed Primary CNS Lymphoma Patients

Registered drugNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:Busulfan
Sponsor:Klinikum Der Landeshauptstadt Stuttgart gKAöR

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Study of Ivosidenib or Enasidenib with Chemotherapy for Patients with Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome with IDH1 or IDH2 Mutation

Investigational

Germany

Participants:18–64 years · 65+ years
Substances:Enasidenib Mesilate
Sponsor:Hemato-Oncologie voor Volwassenen Nederland (Hovon) Stichting

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Study Comparing Standard Chemotherapy with CPX-351 for Adults with Newly Diagnosed Acute Myeloid Leukemia (AML) and Intermediate or Adverse Genetics

Registered drugNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:Cytarabine
Sponsor:Universitaetsklinikum Ulm AöR

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Study of RO7269162 in people at risk for or with early-stage Alzheimer's Disease: Effects on brain amyloid buildup

Registered drug

Germany

Participants:18–64 years · 65+ years
Substances:Florbetaben (18F)
Sponsor:F. Hoffmann-La Roche AG

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Study on Olaparib for Patients with High-Risk HER2-Negative Breast Cancer and BRCA1/2 Mutations After Chemotherapy

Registered drug

Germany

Participants:18–64 years · 65+ years
Substances:Olaparib
Sponsor:AstraZeneca AB

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Study on Adjuvant Therapy with Capecitabine for Stage II Colon and Rectal Cancer Patients with Positive ctDNA After Tumor Removal

Registered drugNo placebo

Germany

Participants:18–64 years · 65+ years
Substances:Capecitabine
Sponsor:Technische Universitaet Dresden

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Clinical research in Bremen

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01 Oncology - Blood Cancers

Groundbreaking research focusing on Acute Myeloid Leukemia (AML) and Chronic Myeloid Leukemia, investigating novel combination therapies and treatment approaches for patients ineligible for intensive chemotherapy.

Novel drug combinations for AML treatment
Gene-specific targeted therapies
Pediatric lymphoma treatments

02 Breast Cancer Research

Comprehensive studies examining various types of breast cancer treatments, with particular focus on triple-negative and HR+/HER2- breast cancers. Research includes evaluation of immunotherapy and targeted therapeutic approaches.

Triple-negative breast cancer therapy
Endocrine therapy optimization
Metastatic disease management

03 Cardiovascular Studies

Innovative research targeting atherosclerotic cardiovascular disease and hypertension, exploring new treatment methods including cholesterol management and blood pressure control techniques.

Lipid-lowering therapies
Hypertension management
Cardiovascular risk reduction

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Clinical trials in Bremen – page 8

118 trials in Bremen

Diffuse large B-cell lymphoma

Study of Copanlisib with Rituximab and CHOP for Untreated Diffuse Large B-Cell Lymphoma in Patients Aged 18-80

Malignant melanoma

Study on Fianlimab and Cemiplimab for Adults with Resectable Stage III and IV Melanoma

Breast cancer+4

Study Comparing Ribociclib and Endocrine Therapy to Chemotherapy for Patients with Intermediate-Risk HR+/HER2- Early Breast Cancer

Study on Reducing Side Effects in Advanced Hodgkin Lymphoma Using Brentuximab Vedotin and Drug Combination for Newly Diagnosed Patients

Study on Reducing Side Effects in Advanced Hodgkin Lymphoma Using Brentuximab Vedotin and Drug Combination for Newly Diagnosed Patients

Rectal cancer

Study Comparing FOLFOX Before Surgery to Risk-Adapted Chemotherapy After Surgery for Patients with Locally Advanced Rectal Cancer and Low Risk of Local Failure

Acute myeloid leukaemia+1

Study on Molidustat and Ivosidenib for Adults with Relapsed or Refractory IDH1-Mutated Acute Myeloid Leukemia or Myelodysplastic Syndrome

Central nervous system lymphoma

Study on De-escalated Induction Therapy with Methotrexate, Cytarabine, Thiotepa, and Rituximab for Newly Diagnosed Primary CNS Lymphoma Patients

Acute myeloid leukaemia+1

Study of Ivosidenib or Enasidenib with Chemotherapy for Patients with Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome with IDH1 or IDH2 Mutation

Acute myeloid leukaemia

Study Comparing Standard Chemotherapy with CPX-351 for Adults with Newly Diagnosed Acute Myeloid Leukemia (AML) and Intermediate or Adverse Genetics

Prodromal Alzheimer's disease

Study of RO7269162 in people at risk for or with early-stage Alzheimer's Disease: Effects on brain amyloid buildup

Breast cancer

Study on Olaparib for Patients with High-Risk HER2-Negative Breast Cancer and BRCA1/2 Mutations After Chemotherapy

Colon cancer stage II+1

Study on Adjuvant Therapy with Capecitabine for Stage II Colon and Rectal Cancer Patients with Positive ctDNA After Tumor Removal

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Clinical trials in Bremen – page 8

118 trials in Bremen

Breast cancer+4

Acute myeloid leukaemia+1

Acute myeloid leukaemia+1

Colon cancer stage II+1

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Clinical research in Bremen

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