This study is looking at Alcohol Use Disorder, which is a condition where a person has difficulty controlling their drinking despite it causing problems in their life. The treatment being tested is called Brenipatide, also known by its code name LY3537031, which is given as an injection under the skin using a pre-filled syringe. Some people in the study will receive Brenipatide while others will receive placebo. The purpose of this study is to see if Brenipatide works better than placebo in helping adults with Alcohol Use Disorder reduce their drinking.
The study is divided into two periods. In the first period, people will receive either Brenipatide at different dose levels or placebo to find out if the medicine can help reduce behaviors related to Alcohol Use Disorder. The study will measure changes in drinking patterns using a method called the Timeline Followback Method, which tracks drinking behavior over time. In the second period, people who responded well to Brenipatide in the first period will continue taking the medicine to see if it can help them maintain the reduction in alcohol use over a longer time.
During the study, people will need to give themselves injections of the study medicine, keep track of their drinking and other information in diaries, attend all required visits, and answer questions about their health and drinking habits. The study will look at how safe the medicine is and whether it helps people who want to stop drinking or cut down on the amount they drink.
Belgium 
Germany 