Anesthesiology and Perioperative Care

At Hospital Universitario Dr Peset Aleixandre, research in Anesthesia and Analgesia and Surgical Procedures focuses on improving comfort, safety, and recovery around operations and critical care.

  • Studies on postoperative pain and rebound pain after regional anaesthesia aim to improve pain control after surgery.
  • Trials in weaning of mechanical ventilation and extubation failure evaluate ways to support safer recovery in intensive care.
  • Research on non-invasive ventilation and high-flow oxygen therapy is designed to improve respiratory support for vulnerable patients.

These studies reflect a practical focus on better perioperative outcomes, safer breathing support, and more effective symptom relief.

Kidney Disease and Renal Protection

Renal research at this site covers Chronic Kidney Disease, End-stage renal disease, and transplant-related conditions, with an emphasis on slowing disease progression and protecting kidney function.

  • Trials in IgA nephropathy, focal segmental glomerulosclerosis, and lupus nephritis are testing new ways to reduce kidney damage.
  • Studies in kidney transplant recipients and chronic active antibody-mediated rejection aim to preserve graft function.
  • Research in dialysis and hyperkalemia looks at improving safety and long-term outcomes in advanced kidney disease.

The overall goal is to evaluate treatments that can better preserve renal function and reduce complications in people living with complex kidney disorders.

Hematology and Blood Cancers

This site conducts extensive work in Hemic and Lymphatic Diseases, especially cancers such as multiple myeloma, lymphoma, leukemia, and myelofibrosis.

  • Studies in newly diagnosed, relapsed, and refractory multiple myeloma are evaluating improved treatment combinations and disease control.
  • Trials in follicular lymphoma, diffuse large B-cell lymphoma, and marginal zone lymphoma are testing more effective cancer therapies.
  • Research in myelofibrosis, essential thrombocythemia, and acute myeloid leukemia is focused on better blood cancer management and response rates.

Much of this work aims to improve survival, deepen treatment responses, and offer new options for patients with difficult-to-treat blood cancers.

Autoimmune and Inflammatory Diseases

Clinical research here includes a strong portfolio in immune system diseases and systemic autoimmune rheumatic diseases, with studies across systemic lupus erythematosus, systemic sclerosis, and related conditions.

  • Trials in systemic lupus erythematosus, cutaneous lupus erythematosus, and lupus nephritis are assessing better disease control.
  • Studies in diffuse cutaneous systemic sclerosis and systemic sclerosis-associated interstitial lung disease are exploring ways to slow progression and protect organ function.
  • Research in Sjögren’s syndrome and bullous pemphigoid is aimed at improving symptom relief and long-term safety of treatment.

These trials are designed to refine immune-targeted care and reduce the burden of chronic inflammatory disease.

Neurology and Neurodegenerative Disorders

Neurology research at Hospital Universitario Dr Peset Aleixandre spans Nervous System Diseases, mental disorders, and age-related cognitive decline, with a major emphasis on Alzheimer’s disease.

  • Studies in Alzheimer disease, mild cognitive impairment, and mild dementia are evaluating treatments that may help preserve memory and daily function.
  • Trials in early Parkinson’s disease and multiple sclerosis are focused on reducing symptoms and improving disease control.
  • Research on biomarkers of inflammation and brain amyloid is helping assess whether new approaches can better track or slow neurodegeneration.

Overall, the site is contributing to both treatment development and earlier understanding of progressive brain disorders.

Respiratory and Allergic Conditions

The site has active studies in Respiratory Tract Diseases, especially asthma, chronic obstructive pulmonary disease, and severe allergic airway disease.

  • Trials in severe eosinophilic asthma and type 2 inflammation are testing better ways to control difficult asthma.
  • Research in COPD is evaluating strategies to improve clinical control and reduce serious cardiopulmonary outcomes.
  • Studies in allergic rhinitis and asthma with allergic features are exploring more effective symptom management.

These projects aim to help patients breathe more easily, reduce flare-ups, and improve long-term respiratory health.

Oncology and Solid Tumors

Oncology research includes Neoplasms affecting the breast, lung, colon, and skin, with trials designed to improve treatment effectiveness and disease-free survival.

  • Studies in breast cancer, including triple-negative breast cancer and HER2-positive breast cancer, are testing better cancer-control strategies.
  • Research in non-small cell lung cancer and metastatic colorectal cancer is focused on improving outcomes for advanced disease.
  • Trials in melanoma are evaluating new immunotherapy approaches for patients with aggressive disease.

These efforts reflect a broad commitment to advancing cancer care through more effective and personalized treatment options.

Cardiovascular and Metabolic Research

The cardiovascular portfolio covers Cardiovascular Diseases and Nutritional and Metabolic Diseases, with attention to risk reduction, prevention, and long-term organ protection.

  • Trials in atherosclerotic cardiovascular disease, heart failure, and acute pulmonary embolism are studying ways to improve survival and prevent complications.
  • Research in chronic kidney disease with diabetes, obesity, and weight management is examining how to reduce combined cardio-renal risk.
  • Studies in recurrent pancreatitis and secondary prevention of vascular events aim to reduce repeat episodes and future cardiovascular events.

This work supports better prevention strategies for patients with overlapping heart, kidney, and metabolic conditions.

Dermatology and Rare Immune Skin Disease

Research in Skin and Connective Tissue Diseases includes immune-mediated skin conditions such as bullous pemphigoid and hidradenitis suppurativa.

  • Trials in bullous pemphigoid are evaluating better long-term control of this blistering skin disease.
  • Studies in hidradenitis suppurativa and cutaneous lupus are focused on improving symptoms and reducing inflammation.
  • Research in non-infectious uveitis also reflects the site’s interest in inflammatory disorders that affect the eyes and immune system.

These investigations aim to improve quality of life for patients with chronic and often hard-to-manage inflammatory conditions.