Oncology and Solid Tumors

At Hospital Universitario Marques De Valdecilla, oncology research is heavily focused on a wide range of cancers, especially advanced and metastatic disease. Studies here are exploring new ways to improve treatment effectiveness, extend survival, and better control disease progression across multiple tumor types.

  • Advanced non-small cell lung cancer, colorectal cancer, gastric cancer, and pancreatic cancer
  • Breast cancer, including HER2-positive, hormone receptor-positive, and triple-negative disease
  • Melanoma, head and neck cancer, urothelial cancer, and other solid tumors

Many of these trials are testing new anticancer therapies or combinations designed to improve responses in patients with hard-to-treat or previously treated cancers.

Hematology and Blood Cancers

The site has a strong program in hematologic malignancies, covering both newly diagnosed and relapsed disease. Research is centered on finding more effective treatments for blood cancers and improving long-term disease control.

  • Multiple myeloma and plasma cell disorders
  • Diffuse large B-cell lymphoma, follicular lymphoma, and mantle cell lymphoma
  • Acute leukemia, including acute lymphoblastic leukemia and acute myeloid leukemia

These studies often aim to improve response rates, deepen remission, and support better outcomes for patients with difficult-to-treat blood cancers.

Gastroenterology and Liver Disease

Clinical trials in digestive system diseases and hepatology include both cancer and non-cancer conditions. The research is addressing chronic liver injury, inflammatory bowel disease, and acute digestive disorders.

  • Non-alcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis, and cirrhosis
  • Hepatitis B, hepatitis C, and other chronic viral liver infections
  • Ulcerative colitis, Crohn’s disease, and acute pancreatitis

The main goals include testing new treatments, improving disease control, and reducing complications in liver and gastrointestinal disorders.

Cardiovascular and Metabolic Research

The site also supports broad research in cardiovascular disease, diabetes, and related metabolic conditions. These trials are designed to lower risk, prevent complications, and improve long-term health in high-risk patients.

  • Acute myocardial infarction, atherosclerotic cardiovascular disease, and heart valve disease
  • Type 2 diabetes, obesity, and overweight
  • Venous thromboembolism, hypertension, and aortic stenosis

Research in this area is often focused on evaluating better prevention strategies and treatment approaches for common but serious cardiometabolic conditions.

Respiratory, Autoimmune, and Inflammatory Diseases

Hospital Universitario Marques De Valdecilla is also active in trials for chronic lung disease, autoimmune disorders, and systemic inflammatory conditions. These studies reflect a strong interest in improving symptom control and reducing flare-ups and organ damage.

  • Asthma, chronic obstructive pulmonary disease, and idiopathic pulmonary fibrosis
  • Rheumatoid arthritis, psoriatic arthritis, and systemic lupus erythematosus
  • Systemic sclerosis, Sjögren’s syndrome, and vasculitis

The purpose of these trials is to test new therapies that may better control inflammation, preserve function, and improve quality of life for patients with chronic immune-mediated disease.

Transplantation, Infections, and Supportive Care

The research portfolio includes important studies in transplant medicine, infectious diseases, and supportive care for patients with complex medical needs. These trials aim to prevent complications and improve recovery after intensive treatment.

  • Graft-versus-host disease, including acute and chronic forms
  • Cytomegalovirus infection, fungal infections, and serious bacterial infections
  • Lung transplant and other post-transplant infection prevention strategies

This area of research is focused on better prevention, safer supportive care, and improved outcomes for patients undergoing cell therapy or transplantation.

Neurology, Psychiatry, and Rare Diseases

The trial landscape also extends into neurological disease, mental health, and selected rare conditions. These studies are exploring ways to slow progression, improve symptoms, and support better daily functioning.

  • Alzheimer’s disease and Parkinson’s disease
  • Migraine and other chronic headache disorders
  • Rare metabolic, genetic, and immune disorders

The main research purpose is to evaluate new treatments and better understand disease mechanisms in conditions where current options remain limited.