Universitaet Leipzig

Liebigstrasse 20, Zentrum-Suedost, Leipzig, 04103, Germany

Skin and Connective Tissue Diseases

At Universitaet Leipzig, clinical research in Dermatology, Venereology, and Allergology is centered on skin and connective tissue diseases, with a strong focus on ulcerative pyoderma gangrenosum. The trials are designed to assess whether new treatment approaches can improve outcomes for patients living with this rare and difficult-to-treat inflammatory condition.

Studies focused on ulcerative pyoderma gangrenosum and related inflammatory skin disorders
Research evaluating the effectiveness and safety of emerging therapies
Clinical work aimed at improving treatment options for complex dermatologic disease

With 6 clinical trials and 106 investigators contributing to the program, the site supports focused research on better therapies for this rare skin disease.

Long-Term Safety Study of Asciminib in Patients With Chronic Myelogenous Leukemia or Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Recruiting

1 1 1 1
Investigated diseases:
- Chronic myeloid leukaemia
Investigated drugs:
+8
ICP-332 for Adults with Prurigo Nodularis

Recruiting

1
Investigated drugs:
- 3-[(3AS,6AR)-5-{5-CHLORO-2-[(1-METHYL-1H-PYRAZOL-4-YL)AMINO]PYRIMIDIN-4-YL}-3A-METHYLHEXAHYDROPYRROLO[3,4-C]PYRROL-2(1H)-YL]-3-OXOPROPANENITRILE
A Study of Teplizumab Compared to Placebo for Blood Sugar Control in Children and Young Adults Aged 1 to 25 Years with Newly Diagnosed Type 1 Diabetes

Recruiting

1 1
Investigated drugs:
- Teplizumab
+4
N1T-MC-MALO: A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes (SYNERGY-Outcomes); N1T-MC-TZ01 Tirzepatide in participants with high-risk MASLD; N1T-MC-RT01 Retatrutide in participants with high-risk MASLD

Recruiting

1 1
Investigated drugs:
- Ly3437943 Sodium
- Tirzepatide
+9
A study of sacituzumab tirumotecan and bevacizumab in patients with newly diagnosed advanced ovarian cancer following first-line platinum-based chemotherapy

Recruiting

1 1 1 1
Investigated drugs:
- Sacituzumab Tirumotecan
- Bevacizumab
+9
Phase 1b-2 Study of Elacestrant and Abemaciclib in Patients with Brain Metastases from ER-Positive, HER2-Negative Breast Cancer

Recruiting

1 1 1
Investigated drugs:
- Elacestrant
- Abemaciclib
A Study of Pembrolizumab and Radiotherapy for Patients with Early-Stage Favorable Classic Hodgkin Lymphoma

Recruiting

1 1 1
Investigated drugs:
- Pembrolizumab
A study testing trontinemab compared to placebo in patients with early Alzheimer’s disease including mild cognitive impairment and mild dementia

Recruiting

1 1 1
Investigated drugs:
Study of Trontinemab Compared to Placebo for Patients with Early Symptomatic Alzheimer’s Disease

Recruiting

1 1 1
Investigated drugs:
+1
Study of Revumenib and Chemotherapy for Patients with Newly Diagnosed Acute Myeloid Leukemia with NPM1 Gene Mutation

Recruiting

1 1 1
Investigated drugs:
+7