This study focuses on Irritable Bowel Syndrome (IBS), specifically the non-constipated type, which is a disorder affecting the digestive system that can cause stomach pain, bloating, and changes in bowel habits. The study will test a treatment called Saccharomyces boulardii CNCM I-745, which is a type of beneficial yeast, comparing it with a placebo. Another medication called loperamide may be used during the study to help manage symptoms.

The purpose of this research is to determine if Saccharomyces boulardii CNCM I-745 can improve overall IBS symptoms when taken over an 8-week period. The treatment will be given in the form of hard capsules that are taken by mouth. The study will measure how the treatment affects various aspects of the condition, including stomach pain, bloating, and overall quality of life.

During the study, participants will take either the treatment or placebo for 12 weeks. The researchers will monitor any changes in symptoms throughout this period and continue observations for some time after the treatment ends. They will also keep track of any side effects that might occur during the study period. The study is designed so that neither the participants nor the doctors know who is receiving the actual treatment or the placebo until the study is complete.