[18F]-DPA-714 is a special imaging tracer used in PET scans that helps doctors see inflammation in the brain by showing active microglia cells. This helps understand how the brain’s immune system is responding in Alzheimer’s disease.

[18F]-Ro948 is an imaging tracer that binds to abnormal tau protein in the brain during PET scans. This helps visualize the buildup of tau, which is one of the hallmark features of Alzheimer’s disease.

[11C]-UCB-J is a newer type of imaging tracer that shows the density and health of synapses (connections between brain cells) during PET scans. This helps doctors understand how Alzheimer’s disease affects the communication between brain cells.

Alzheimer’s Disease – A progressive brain disorder that gradually destroys memory, thinking skills, and the ability to carry out simple tasks. It begins with mild memory problems and confusion, which slowly worsen over time. The disease causes brain cells to degenerate and die, leading to a decline in cognitive and behavioral functions. Changes in the brain include abnormal buildup of proteins called plaques and tangles. People with Alzheimer’s experience increasing difficulty with daily activities as their judgment and sense of orientation become impaired. The condition affects each person differently, but typically progresses from mild to moderate to severe stages.

Note: I corrected the spelling from “Alzeihmer disease” to “Alzheimer’s Disease” as per the requirement to use correct, medically recognized names.