Levetiracetam is an anti-seizure medication used to prevent and control epileptic seizures. In this trial, it is being studied as a preventive treatment for seizures in adults who have both Down syndrome and Alzheimer’s disease. The medication works by decreasing abnormal brain activity that can lead to seizures. It is already commonly used to treat epilepsy in the general population, and researchers are studying if it can help prevent seizures specifically in people with Down syndrome who develop Alzheimer’s disease.

Alzheimer’s Disease – A progressive brain disorder that gradually destroys memory and thinking abilities. It begins with mild memory loss and can progress to losing the ability to carry on conversations and respond to the environment. The disease causes brain cells to degenerate and die, leading to a decline in cognitive and physical functions. Changes in the brain may begin years before the first symptoms appear.

Down Syndrome – A genetic condition caused by the presence of an extra copy of chromosome 21. It leads to developmental delays and distinct physical features, including a flattened face and upward slanting eyes. People with Down syndrome often experience slower physical development and mild to moderate intellectual disability. The condition can affect cognitive ability, physical growth, and facial features.