Metformin is a commonly prescribed diabetes medication that helps control blood sugar levels. It works by improving how your body responds to insulin and reducing the amount of sugar your liver produces. In this trial, it is being studied to see if it can help maintain diabetes remission in patients who have undergone bariatric surgery. Bariatric surgery often helps patients achieve diabetes remission, and this medication is being tested to potentially extend this benefit.

Bariatric Surgery (BS) is a surgical procedure that helps with weight loss by making changes to your digestive system. While not a medication, it is a key therapeutic intervention in this trial. The surgery can help people lose weight and often leads to improvement or remission of type 2 diabetes.

Type 2 Diabetes – A metabolic disorder characterized by high blood sugar levels due to the body’s ineffective use of insulin or insufficient insulin production. The condition develops gradually, often beginning with insulin resistance, where body cells don’t respond effectively to insulin. Over time, this leads to consistently elevated blood glucose levels, affecting how the body processes sugar. The disease typically appears in adults and is often associated with lifestyle factors and genetic predisposition. Common manifestations include increased thirst, frequent urination, fatigue, and slow healing of wounds. The condition can progress over years, with varying degrees of severity.

Post-Bariatric Surgery Diabetes Remission – A condition where diabetes symptoms improve or disappear following weight-loss surgery. This state occurs when blood sugar levels return to normal ranges without the need for diabetes medications after bariatric surgery. The improvement can be partial or complete, depending on blood sugar control levels. The remission may happen gradually as the body adjusts to the changes following surgery. The condition requires ongoing monitoring of blood sugar levels to confirm sustained improvement.